| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
A Biofunctional Molecular Beacon for Detecting Single Base Mutations in Cancer Cells
|
Dong, Haiyan
|
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5 |
C |
p.
|
artikel
|
| 2 |
A Broad Range of Dose Optima Achieve High-level, Long-term Gene Expression After Hydrodynamic Delivery of Sleeping Beauty Transposons Using Hyperactive SB100x Transposase
|
Podetz-Pedersen, Kelly M
|
|
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5 |
C |
p.
|
artikel
|
| 3 |
Acid-Sensitive Sheddable PEGylated PLGA Nanoparticles Increase the Delivery of TNF-α siRNA in Chronic Inflammation Sites
|
Aldayel, Abdulaziz M
|
|
|
5 |
C |
p.
|
artikel
|
| 4 |
Activation of Fetal γ-globin Gene Expression via Direct Protein Delivery of Synthetic Zinc-finger DNA-Binding Domains
|
Hossain, Mir A
|
|
|
5 |
C |
p.
|
artikel
|
| 5 |
A Gene Gun-mediated Nonviral RNA trans-splicing Strategy for Col7a1 Repair
|
Peking, Patricia
|
|
|
5 |
C |
p.
|
artikel
|
| 6 |
A Glu-urea-Lys Ligand-conjugated Lipid Nanoparticle/siRNA System Inhibits Androgen Receptor Expression In Vivo
|
Lee, Justin B
|
|
|
5 |
C |
p.
|
artikel
|
| 7 |
A High-Capacity Adenoviral Hybrid Vector System Utilizing the Hyperactive Sleeping Beauty Transposase SB100X for Enhanced Integration
|
Boehme, Philip
|
|
|
5 |
C |
p.
|
artikel
|
| 8 |
Altered Levels of MicroRNA-9, -206, and -132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy
|
Catapano, Francesco
|
|
|
5 |
C |
p.
|
artikel
|
| 9 |
A MicroRNA Panel in Pancreatic Cyst Fluid for the Risk Stratification of Pancreatic Cysts in a Prospective Cohort
|
Utomo, WK
|
|
|
5 |
C |
p.
|
artikel
|
| 10 |
An Amphiphilic Peptide Induces Apoptosis Through the miR29b-p53 Pathway in Cancer Cells
|
Kim, Soyoung
|
|
|
5 |
C |
p.
|
artikel
|
| 11 |
An Efficient Method for Generation of Transgenic Rats Avoiding Embryo Manipulation
|
Pradhan, Bhola Shankar
|
|
|
5 |
C |
p.
|
artikel
|
| 12 |
A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry
|
Maier, Keith E
|
|
|
5 |
C |
p.
|
artikel
|
| 13 |
An Exon-Specific U1snRNA Induces a Robust Factor IX Activity in Mice Expressing Multiple Human FIX Splicing Mutants
|
Balestra, Dario
|
|
|
5 |
C |
p.
|
artikel
|
| 14 |
A Novel PD-L1-targeting Antagonistic DNA Aptamer With Antitumor Effects
|
Lai, Wei-Yun
|
|
|
5 |
C |
p.
|
artikel
|
| 15 |
A Novel p19 Fusion Protein as a Delivery Agent for Short-interfering RNAs
|
Danielson, Dana C
|
|
|
5 |
C |
p.
|
artikel
|
| 16 |
Antisense Oligonucleotide-based Splice Correction for USH2A-associated Retinal Degeneration Caused by a Frequent Deep-intronic Mutation
|
Slijkerman, Radulfus WN
|
|
|
5 |
C |
p.
|
artikel
|
| 17 |
Antisense Oligonucleotide-mediated Exon Skipping as a Systemic Therapeutic Approach for Recessive Dystrophic Epidermolysis Bullosa
|
Bremer, Jeroen
|
|
|
5 |
C |
p.
|
artikel
|
| 18 |
Antisense Oligonucleotide Mediated Splice Correction of a Deep Intronic Mutation in OPA1
|
Bonifert, Tobias
|
|
|
5 |
C |
p.
|
artikel
|
| 19 |
Application of Peptide Nucleic Acid-based Assays Toward Detection of Somatic Mosaicism
|
Hong, Christopher S
|
|
|
5 |
C |
p.
|
artikel
|
| 20 |
Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL
|
Iaboni, Margherita
|
|
|
5 |
C |
p.
|
artikel
|
| 21 |
A Small Indel Mutant Mouse Model of Epidermolytic Palmoplantar Keratoderma and Its Application to Mutant-specific shRNA Therapy
|
Lyu, Ya-Su
|
|
|
5 |
C |
p.
|
artikel
|
| 22 |
A Tat-conjugated Peptide Nucleic Acid Tat-PNA-DR Inhibits Hepatitis B Virus Replication In Vitro and In Vivo by Targeting LTR Direct Repeats of HBV RNA
|
Zeng, Zhengyang
|
|
|
5 |
C |
p.
|
artikel
|
| 23 |
A Traceless Selection: Counter-selection System That Allows Efficient Generation of Transposon and CRISPR-modified T-cell Products
|
Mezzadra, Riccardo
|
|
|
5 |
C |
p.
|
artikel
|
| 24 |
A Tumor-specific MicroRNA Recognition System Facilitates the Accurate Targeting to Tumor Cells by Magnetic Nanoparticles
|
Yu, Yingting
|
|
|
5 |
C |
p.
|
artikel
|
| 25 |
Biodistribution and Pharmacokinetics Study of siRNA-loaded Anti-NTSR1-mAb-functionalized Novel Hybrid Nanoparticles in a Metastatic Orthotopic Murine Lung Cancer Model
|
Perepelyuk, Maryna
|
|
|
5 |
C |
p.
|
artikel
|
| 26 |
Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells
|
Moroz, Elena
|
|
|
5 |
C |
p.
|
artikel
|
| 27 |
Characterization of MNK1b DNA Aptamers That Inhibit Proliferation in MDA-MB231 Breast Cancer Cells
|
García-Recio, Eva M
|
|
|
5 |
C |
p.
|
artikel
|
| 28 |
CNS-restricted Transduction and CRISPR/Cas9-mediated Gene Deletion with an Engineered AAV Vector
|
Murlidharan, Giridhar
|
|
|
5 |
C |
p.
|
artikel
|
| 29 |
Combination of microRNA-21 and microRNA-146a Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction in Mice
|
Huang, Wei
|
|
|
5 |
C |
p.
|
artikel
|
| 30 |
Conjugate-SELEX: A High-throughput Screening of Thioaptamer-liposomal Nanoparticle Conjugates for Targeted Intracellular Delivery of Anticancer Drugs
|
Mu, Qingshan
|
|
|
5 |
C |
p.
|
artikel
|
| 31 |
Corrigendum to “Antisense Oligonucleotide Mediated Splice Correction of a Deep Intronic Mutation in OPA1”
|
|
|
|
5 |
C |
p.
|
artikel
|
| 32 |
Corrigendum to “Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method”
|
|
|
|
5 |
C |
p.
|
artikel
|
| 33 |
Corrigendum to “From Cryptic Toward Canonical Pre-mRNA Splicing in Pompe Disease: a Pipeline for the Development of Antisense Oligonucleotides”
|
|
|
|
5 |
C |
p.
|
artikel
|
| 34 |
Corrigendum to GFP to BFP Conversion: A Versatile Assay for the Quantification of CRISPR/Cas9-mediated Genome Editing
|
Glaser, Astrid
|
|
|
5 |
C |
p.
|
artikel
|
| 35 |
CRISPR/Cas9-AAV Mediated Knock-in at NRL Locus in Human Embryonic Stem Cells
|
Ge, Xianglian
|
|
|
5 |
C |
p.
|
artikel
|
| 36 |
CRISPR-Cas9 for in vivo Gene Therapy: Promise and Hurdles
|
Dai, Wei-Jing
|
|
|
5 |
C |
p.
|
artikel
|
| 37 |
CRISPR-Cas9 System as a Versatile Tool for Genome Engineering in Human Cells
|
Wang, Xuelian
|
|
|
5 |
C |
p.
|
artikel
|
| 38 |
Cytosolic DNA Sensor Upregulation Accompanies DNA Electrotransfer in B16.F10 Melanoma Cells
|
Znidar, Katarina
|
|
|
5 |
C |
p.
|
artikel
|
| 39 |
Deciphering relationship between microhomology and in-frame mutation occurrence in human CRISPR-based gene knockout
|
Chuai, Guohui
|
|
|
5 |
C |
p.
|
artikel
|
| 40 |
Defibrotide (Defitelio): A New Addition to the Stockpile of Food and Drug Administration-approved Oligonucleotide Drugs
|
Stein, Cy
|
|
|
5 |
C |
p.
|
artikel
|
| 41 |
Design, Characterization, and Lead Selection of Therapeutic miRNAs Targeting Huntingtin for Development of Gene Therapy for Huntington's Disease
|
Miniarikova, Jana
|
|
|
5 |
C |
p.
|
artikel
|
| 42 |
Design of Effective Primary MicroRNA Mimics With Different Basal Stem Conformations
|
van den Berg, Fiona T
|
|
|
5 |
C |
p.
|
artikel
|
| 43 |
Development of Lentiviral Vectors Simultaneously Expressing Multiple siRNAs Against CCR5, vif and tat/rev Genes for an HIV-1 Gene Therapy Approach
|
Spanevello, Francesca
|
|
|
5 |
C |
p.
|
artikel
|
| 44 |
Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a) in Mice
|
Yu, Rosie Z
|
|
|
5 |
C |
p.
|
artikel
|
| 45 |
DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization
|
Heissig, Philipp
|
|
|
5 |
C |
p.
|
artikel
|
| 46 |
DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations
|
Schnödt, Maria
|
|
|
5 |
C |
p.
|
artikel
|
| 47 |
Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain
|
Nikan, Mehran
|
|
|
5 |
C |
p.
|
artikel
|
| 48 |
Double-target Antisense U1snRNAs Correct Mis-splicing Due to c.639+861C>T and c.639+919G>A GLA Deep Intronic Mutations
|
Ferri, Lorenzo
|
|
|
5 |
C |
p.
|
artikel
|
| 49 |
Ecdysone Receptor-based Singular Gene Switches for Regulated Transgene Expression in Cells and Adult Rodent Tissues
|
Lee, Seoghyun
|
|
|
5 |
C |
p.
|
artikel
|
| 50 |
Effective Prevention of Liver Fibrosis by Liver-targeted Hydrodynamic Gene Delivery of Matrix Metalloproteinase-13 in a Rat Liver Fibrosis Model
|
Abe, Hiroyuki
|
|
|
5 |
C |
p.
|
artikel
|
| 51 |
Effects of Fibrotic Tissue on Liver-targeted Hydrodynamic Gene Delivery
|
Kobayashi, Yuji
|
|
|
5 |
C |
p.
|
artikel
|
| 52 |
Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair
|
Wang, Kankan
|
|
|
5 |
C |
p.
|
artikel
|
| 53 |
Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance
|
Romano Ibarra, Guillermo S
|
|
|
5 |
C |
p.
|
artikel
|
| 54 |
Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method
|
Iyombe-Engembe, Jean-Paul
|
|
|
5 |
C |
p.
|
artikel
|
| 55 |
Electrotransfer parameters as a tool for controlled and targeted gene expression in skin
|
Kos, Spela
|
|
|
5 |
C |
p.
|
artikel
|
| 56 |
Elucidation of the Biotransformation Pathways of a Galnac3-conjugated Antisense Oligonucleotide in Rats and Monkeys
|
Shemesh, Colby S
|
|
|
5 |
C |
p.
|
artikel
|
| 57 |
Endocytosis and Endosomal Trafficking of DNA After Gene Electrotransfer In Vitro
|
Rosazza, Christelle
|
|
|
5 |
C |
p.
|
artikel
|
| 58 |
Enhanced Anticancer Activity of PF-04691502, a Dual PI3K/mTOR Inhibitor, in Combination With VEGF siRNA Against Non–small-cell Lung Cancer
|
Espana-Serrano, Laura
|
|
|
5 |
C |
p.
|
artikel
|
| 59 |
Episomal Nonviral Gene Therapy Vectors Slow Progression of Atherosclerosis in a Model of Familial Hypercholesterolemia
|
Kerr, Alastair G
|
|
|
5 |
C |
p.
|
artikel
|
| 60 |
Escape Mutations, Ganciclovir Resistance, and Teratoma Formation in Human iPSCs Expressing an HSVtk Suicide Gene
|
Kotini, Andriana G
|
|
|
5 |
C |
p.
|
artikel
|
| 61 |
E-selectin Targeting PEGylated-thioaptamer Prevents Breast Cancer Metastases
|
Morita, Yoshihiro
|
|
|
5 |
C |
p.
|
artikel
|
| 62 |
18F-FDG PET/CT for Monitoring the Response of Breast Cancer to miR-143-Based Therapeutics by Targeting Tumor Glycolysis
|
Miao, Ying
|
|
|
5 |
C |
p.
|
artikel
|
| 63 |
Flexible, AAV-equipped Genetic Modules for Inducible Control of Gene Expression in Mammalian Brain
|
Dogbevia, Godwin K
|
|
|
5 |
C |
p.
|
artikel
|
| 64 |
From Cryptic Toward Canonical Pre-mRNA Splicing in Pompe Disease: a Pipeline for the Development of Antisense Oligonucleotides
|
Bergsma, Atze J
|
|
|
5 |
C |
p.
|
artikel
|
| 65 |
Fructose Promotes Uptake and Activity of Oligonucleotides With Different Chemistries in a Context-dependent Manner in mdx Mice
|
Cao, Limin
|
|
|
5 |
C |
p.
|
artikel
|
| 66 |
Full-length Dysferlin Transfer by the Hyperactive Sleeping Beauty Transposase Restores Dysferlin-deficient Muscle
|
Escobar, Helena
|
|
|
5 |
C |
p.
|
artikel
|
| 67 |
Galaxy Workflows for Web-based Bioinformatics Analysis of Aptamer High-throughput Sequencing Data
|
Thiel, William H
|
|
|
5 |
C |
p.
|
artikel
|
| 68 |
Gene Editing for the Efficient Correction of a Recurrent COL7A1 Mutation in Recessive Dystrophic Epidermolysis Bullosa Keratinocytes
|
Chamorro, Cristina
|
|
|
5 |
C |
p.
|
artikel
|
| 69 |
Gene Silencing Using 4′-thioDNA as an Artificial Template to Synthesize Short Hairpin RNA Without Inducing a Detectable Innate Immune Response
|
Tarashima, Noriko
|
|
|
5 |
C |
p.
|
artikel
|
| 70 |
GFP to BFP Conversion: A Versatile Assay for the Quantification of CRISPR/Cas9-mediated Genome Editing
|
Glaser, Astrid
|
|
|
5 |
C |
p.
|
artikel
|
| 71 |
Hairpin Ribozyme Genes Curtail Alcohol Drinking: from Rational Design to in vivo Effects in the Rat
|
Sapag, Amalia
|
|
|
5 |
C |
p.
|
artikel
|
| 72 |
Hemagglutinin-targeting Artificial MicroRNAs Expressed by Adenovirus Protect Mice From Different Clades of H5N1 Infection
|
Tang, Xinying
|
|
|
5 |
C |
p.
|
artikel
|
| 73 |
Homology Requirements for Efficient, Footprintless Gene Editing at the CFTR Locus in Human iPSCs with Helper-dependent Adenoviral Vectors
|
Palmer, Donna J
|
|
|
5 |
C |
p.
|
artikel
|
| 74 |
Inhibition of Influenza Virus Replication by DNA Aptamers Targeting a Cellular Component of Translation Initiation
|
Rodriguez, Paloma
|
|
|
5 |
C |
p.
|
artikel
|
| 75 |
Inhibition of miR-155 Protects Against LPS-induced Cardiac Dysfunction and Apoptosis in Mice
|
Wang, Hui
|
|
|
5 |
C |
p.
|
artikel
|
| 76 |
In Silico Aptamer Docking Studies: From a Retrospective Validation to a Prospective Case Study'TIM3 Aptamers Binding
|
Rabal, Obdulia
|
|
|
5 |
C |
p.
|
artikel
|
| 77 |
In vivo Editing of the Human Mutant Rhodopsin Gene by Electroporation of Plasmid-based CRISPR/Cas9 in the Mouse Retina
|
Latella, Maria Carmela
|
|
|
5 |
C |
p.
|
artikel
|
| 78 |
In Vivo Selection Against Human Colorectal Cancer Xenografts Identifies an Aptamer That Targets RNA Helicase Protein DHX9
|
Mi, Jing
|
|
|
5 |
C |
p.
|
artikel
|
| 79 |
In Vivo siRNA Delivery Using JC Virus-like Particles Decreases the Expression of RANKL in Rats
|
Hoffmann, Daniel B
|
|
|
5 |
C |
p.
|
artikel
|
| 80 |
iRNA-PseU: Identifying RNA pseudouridine sites
|
Chen, Wei
|
|
|
5 |
C |
p.
|
artikel
|
| 81 |
Knocking Down TMPRSS2-ERG Fusion Oncogene by siRNA Could be an Alternative Treatment to Flutamide
|
Urbinati, Giorgia
|
|
|
5 |
C |
p.
|
artikel
|
| 82 |
Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency
|
Sork, Helena
|
|
|
5 |
C |
p.
|
artikel
|
| 83 |
Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo
|
Basha, Genc
|
|
|
5 |
C |
p.
|
artikel
|
| 84 |
Lipid Nanoparticle-mediated siRNA Transfer Against PCTAIRE1/PCTK1/Cdk16 Inhibits In Vivo Cancer Growth
|
Yanagi, Teruki
|
|
|
5 |
C |
p.
|
artikel
|
| 85 |
LiPS-A3S, a human genomic site for robust expression of inserted transgenes
|
Kotini, Andriana G
|
|
|
5 |
C |
p.
|
artikel
|
| 86 |
Long Intergenic Noncoding RNA 00511 Acts as an Oncogene in Non–small-cell Lung Cancer by Binding to EZH2 and Suppressing p57
|
Sun, Cheng-Cao
|
|
|
5 |
C |
p.
|
artikel
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| 87 |
MicroRNA-27b Enhances the Hepatic Regenerative Properties of Adipose-Derived Mesenchymal Stem Cells
|
Chen, Kuang-Den
|
|
|
5 |
C |
p.
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artikel
|
| 88 |
microRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1β-induced Osteoarthritis
|
Karlsen, Tommy A
|
|
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5 |
C |
p.
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artikel
|
| 89 |
Neutrophils are Essential in Short Hairpin RNA of Indoleamine 2,3- Dioxygenase Mediated-antitumor Efficiency
|
Liu, Kuan-Ting
|
|
|
5 |
C |
p.
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artikel
|
| 90 |
Notch-1 Confers Chemoresistance in Lung Adenocarcinoma to Taxanes through AP-1/microRNA-451 Mediated Regulation of MDR-1
|
Huang, Jiayuan
|
|
|
5 |
C |
p.
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artikel
|
| 91 |
Nucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry–based imaging
|
Subramanian, Nithya
|
|
|
5 |
C |
p.
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artikel
|
| 92 |
Overcoming the Specific Toxicity of Large Plasmids Electrotransfer in Primary Cells In Vitro
|
Lesueur, Léa L
|
|
|
5 |
C |
p.
|
artikel
|
| 93 |
Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon
|
Broos, Katrijn
|
|
|
5 |
C |
p.
|
artikel
|
| 94 |
pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences
|
Grier, Alexandra E
|
|
|
5 |
C |
p.
|
artikel
|
| 95 |
Pharmacokinetics and Pharmacodynamics of a 13-mer LNA-inhibitor-miR-221 in Mice and Non-human Primates
|
Gallo Cantafio, Maria Eugenia
|
|
|
5 |
C |
p.
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artikel
|
| 96 |
Pharmacokinetics and Pharmacodynamics of a 13-mer LNA-inhibitor-miR-221 in Mice and Non-human Primates
|
|
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|
5 |
C |
p.
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artikel
|
| 97 |
Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice
|
Wang, Mingxing
|
|
|
5 |
C |
p.
|
artikel
|
| 98 |
Reactivating Fetal Hemoglobin Expression in Human Adult Erythroblasts Through BCL11A Knockdown Using Targeted Endonucleases
|
Bjurström, Carmen F
|
|
|
5 |
C |
p.
|
artikel
|
| 99 |
Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors
|
Koblas, Tomas
|
|
|
5 |
C |
p.
|
artikel
|
| 100 |
Reprogramming the Dynamin 2 mRNA by Spliceosome-mediated RNA Trans-splicing
|
Trochet, Delphine
|
|
|
5 |
C |
p.
|
artikel
|
| 101 |
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells
|
Lee, Patrick C
|
|
|
5 |
C |
p.
|
artikel
|
| 102 |
RETRACTED: miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage-mediated Tumor Cell Metastasis by Targeting KLF6 and C/EBPα
|
Bi, Jia
|
|
|
5 |
C |
p.
|
artikel
|
| 103 |
Selection and Characterization of an α6β4 Integrin blocking DNA Aptamer
|
Berg, Katharina
|
|
|
5 |
C |
p.
|
artikel
|
| 104 |
Selection of a Novel Aptamer Against Vitronectin Using Capillary Electrophoresis and Next Generation Sequencing
|
Stuart, Christopher H
|
|
|
5 |
C |
p.
|
artikel
|
| 105 |
Silencing CCR2 in Macrophages Alleviates Adipose Tissue Inflammation and the Associated Metabolic Syndrome in Dietary Obese Mice
|
Kim, Jongkil
|
|
|
5 |
C |
p.
|
artikel
|
| 106 |
Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth
|
Khan, Tayeba
|
|
|
5 |
C |
p.
|
artikel
|
| 107 |
Systematic Analysis of Long Noncoding RNAs in the Senescence-accelerated Mouse Prone 8 Brain Using RNA Sequencing
|
Zhang, Shuai
|
|
|
5 |
C |
p.
|
artikel
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| 108 |
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Suzuki, Shingo
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Abushahba, Mostafa FN
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Sun, Cheng-Cao
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The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b
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Li, Jia
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Ho, Joan K
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