| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input
|
Yang, Ka
|
|
|
|
3 |
p. 565-576.e4
|
artikel
|
| 2 |
Acid-Tolerant Monomeric GFP from Olindias formosa
|
Shinoda, Hajime
|
|
2018
|
|
3 |
p. 330-338.e7
|
artikel
|
| 3 |
A Decade of Click Chemistry in Protein Palmitoylation: Impact on Discovery and New Biology
|
Gao, Xinxin
|
|
2018
|
|
3 |
p. 236-246
|
artikel
|
| 4 |
A “Double Click” for Illuminating Plant Cell Walls
|
Tobimatsu, Yuki
|
|
2017
|
|
3 |
p. 246-247
|
artikel
|
| 5 |
Advancing protein therapeutics through proximity-induced chemistry
|
Cheng, Linqi
|
|
|
|
3 |
p. 428-445
|
artikel
|
| 6 |
Advancing the Frontiers of Chemical Protein Synthesis—The 7th CPS Meeting, Haifa, Israel
|
Conibear, Anne C.
|
|
2018
|
|
3 |
p. 247-254
|
artikel
|
| 7 |
A Genetic Toggle for Chemical Control of Individual Plk1 Substrates
|
Johnson, James M.
|
|
|
|
3 |
p. 350-362.e8
|
artikel
|
| 8 |
Ainsliadimer A induces ROS-mediated apoptosis in colorectal cancer cells via directly targeting peroxiredoxin 1 and 2
|
Lv, Chao
|
|
|
|
3 |
p. 295-307.e5
|
artikel
|
| 9 |
A Molecular Mechanism for Sequential Activation of a G Protein-Coupled Receptor
|
Grundmann, Manuel
|
|
2016
|
|
3 |
p. 392-403
12 p.
|
artikel
|
| 10 |
An N terminomics toolbox combining 2-pyridinecarboxaldehyde probes and click chemistry for profiling protease specificity
|
Bridge, Haley N.
|
|
|
|
3 |
p. 534-549.e8
|
artikel
|
| 11 |
A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
|
Xu, Chenxi
|
|
|
|
3 |
p. 386-397.e9
|
artikel
|
| 12 |
A Promising CPS1 Inhibitor Keeping Ammonia from Fueling Cancer
|
Taguchi, Ayumu
|
|
|
|
3 |
p. 253-254
|
artikel
|
| 13 |
A proximity labeling-based orthogonal trap strategy identifies HDAC8 promotes cell motility by modulating cortactin acetylation
|
Huang, Yepei
|
|
|
|
3 |
p. 514-522.e4
|
artikel
|
| 14 |
Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6
|
Qiu, Nan
|
|
|
|
3 |
p. 530-537.e7
|
artikel
|
| 15 |
A Systems Chemoproteomic Analysis of Acyl-CoA/Protein Interaction Networks
|
Levy, Michaella J.
|
|
|
|
3 |
p. 322-333.e5
|
artikel
|
| 16 |
Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA
|
Good, James A.D.
|
|
2016
|
|
3 |
p. 404-414
11 p.
|
artikel
|
| 17 |
Bioorthogonal chemistry for biological insights
|
|
|
|
|
3 |
p. 373-374
|
artikel
|
| 18 |
Bioorthogonal click labeling of an amber-free HIV-1 provirus for in-virus single molecule imaging
|
Ao, Yuanyun
|
|
|
|
3 |
p. 487-501.e7
|
artikel
|
| 19 |
Blending Quadruplexes and Bordeaux: A Grand Cru!
|
Yatsunyk, Liliya A.
|
|
2016
|
|
3 |
p. 320-329
10 p.
|
artikel
|
| 20 |
BLISS: A Bioorthogonal Dual-Labeling Strategy to Unravel Lignification Dynamics in Plants
|
Lion, Cedric
|
|
2017
|
|
3 |
p. 326-338
|
artikel
|
| 21 |
Capturing the Structure of the Substrate Bound Condensation Domain
|
Kittilä, Tiia
|
|
2016
|
|
3 |
p. 315-316
2 p.
|
artikel
|
| 22 |
Catching Sirtuin-2 Intermediates One Structure at the Time
|
Lee, Schuyler
|
|
2017
|
|
3 |
p. 248-249
|
artikel
|
| 23 |
Cell-selective bioorthogonal labeling
|
Huang, Wei
|
|
|
|
3 |
p. 409-427
|
artikel
|
| 24 |
Chemical Genetics Reveals Environment-Specific Roles for Quorum Sensing Circuits in Pseudomonas aeruginosa
|
Welsh, Michael A.
|
|
2016
|
|
3 |
p. 361-369
9 p.
|
artikel
|
| 25 |
Chemical immunology: Recent advances in tool development and applications
|
Shi, Yujie
|
|
|
|
3 |
p. 387-408
|
artikel
|
| 26 |
Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction
|
Yang, Jun
|
|
|
|
3 |
p. 278-294.e11
|
artikel
|
| 27 |
Chemical Inhibition of Pre-mRNA Splicing in Living Saccharomyces cerevisiae
|
Hansen, Sarah R.
|
|
2019
|
|
3 |
p. 443-448.e3
|
artikel
|
| 28 |
Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases
|
Bloudoff, Kristjan
|
|
2016
|
|
3 |
p. 331-339
9 p.
|
artikel
|
| 29 |
Chemical proteomics to study metabolism, a reductionist approach applied at the systems level
|
Ali, Md Yousuf
|
|
|
|
3 |
p. 446-451
|
artikel
|
| 30 |
Chemoproteomic-enabled phenotypic screening
|
Conway, Louis P.
|
|
|
|
3 |
p. 371-393
|
artikel
|
| 31 |
Combating the myth of “innate genius” in science
|
Nachtergaele, Sigrid
|
|
|
|
3 |
p. 376-379
|
artikel
|
| 32 |
Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites
|
Lee, Joyce H.
|
|
|
|
3 |
p. 476-489.e6
|
artikel
|
| 33 |
Covalent hitchhikers guide proteins to the nucleus
|
Russell, Alexander F.
|
|
|
|
3 |
p. 383-386
|
artikel
|
| 34 |
Cyclization Reaction-Based Turn-on Probe for Covalent Labeling of Target Proteins
|
Kojima, Hiroyuki
|
|
|
|
3 |
p. 334-349.e11
|
artikel
|
| 35 |
DAGL-Beta Functions as a PUFA-Specific Triacylglycerol Lipase in Macrophages
|
Shin, Myungsun
|
|
|
|
3 |
p. 314-321.e5
|
artikel
|
| 36 |
Deacylation Mechanism by SIRT2 Revealed in the 1′-SH-2′-O-Myristoyl Intermediate Structure
|
Wang, Yi
|
|
2017
|
|
3 |
p. 339-345
|
artikel
|
| 37 |
Degradation of NSD3: What to Myc of it all?
|
Green, Adam I.
|
|
|
|
3 |
p. 356-357
|
artikel
|
| 38 |
Development of Photocrosslinking Probes Based on Huwentoxin-IV to Map the Site of Interaction on Nav1.7
|
Tzakoniati, Foteini
|
|
|
|
3 |
p. 306-313.e4
|
artikel
|
| 39 |
Directed Evolution of a Bright Near-Infrared Fluorescent Rhodopsin Using a Synthetic Chromophore
|
Herwig, Lukas
|
|
2017
|
|
3 |
p. 415-425
|
artikel
|
| 40 |
Directed Non-targeted Mass Spectrometry and Chemical Networking for Discovery of Eicosanoids and Related Oxylipins
|
Watrous, Jeramie D.
|
|
2019
|
|
3 |
p. 433-442.e4
|
artikel
|
| 41 |
Discovering Anti-cancer Immune Enhancers in a Miniaturized Immune-Tumor Microenvironment
|
Huber, Andrew D.
|
|
2019
|
|
3 |
p. 314-316
|
artikel
|
| 42 |
Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy
|
Bonazzi, Simone
|
|
|
|
3 |
p. 235-247.e12
|
artikel
|
| 43 |
Discovery of Small-Molecule Inhibitors of the HSP90-Calcineurin-NFAT Pathway against Glioblastoma
|
Liu, Zhenzhen
|
|
2019
|
|
3 |
p. 352-365.e7
|
artikel
|
| 44 |
Drug Repurposing Approach Identifies Inhibitors of the Prototypic Viral Transcription Factor IE2 that Block Human Cytomegalovirus Replication
|
Mercorelli, Beatrice
|
|
2016
|
|
3 |
p. 340-351
12 p.
|
artikel
|
| 45 |
Elevation of Fumarate Levels Compromise Redox Control and Viability in Mycobacterium tuberculosis
|
Ahn, Yong-Mo
|
|
2017
|
|
3 |
p. 243-245
|
artikel
|
| 46 |
Engineering a Multifunctional Nitroreductase for Improved Activation of Prodrugs and PET Probes for Cancer Gene Therapy
|
Copp, Janine N.
|
|
2017
|
|
3 |
p. 391-403
|
artikel
|
| 47 |
Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4
|
Zheng, Qingfei
|
|
2016
|
|
3 |
p. 352-360
9 p.
|
artikel
|
| 48 |
Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State
|
Magtanong, Leslie
|
|
2019
|
|
3 |
p. 420-432.e9
|
artikel
|
| 49 |
Flaming Mitochondria: The Anti-inflammatory Drug Leflunomide Boosts Mitofusins
|
Pellattiero, Anna
|
|
2018
|
|
3 |
p. 231-233
|
artikel
|
| 50 |
FLEX: genetically encodable enzymatic fluorescence signal amplification using engineered peroxidase
|
Sharma, Nirmali
|
|
|
|
3 |
p. 502-513.e6
|
artikel
|
| 51 |
Fluorescent RNA Aptamers as a Tool to Study RNA-Modifying Enzymes
|
Svensen, Nina
|
|
2016
|
|
3 |
p. 415-425
11 p.
|
artikel
|
| 52 |
Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects
|
Ye, Qing
|
|
2019
|
|
3 |
p. 366-377.e12
|
artikel
|
| 53 |
FRET-Based Sensors Unravel Activation and Allosteric Modulation of the GABAB Receptor
|
Lecat-Guillet, Nathalie
|
|
2017
|
|
3 |
p. 360-370
|
artikel
|
| 54 |
Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis
|
Ruecker, Nadine
|
|
2017
|
|
3 |
p. 306-315
|
artikel
|
| 55 |
Functional and Structural Analysis of Programmed C-Methylation in the Biosynthesis of the Fungal Polyketide Citrinin
|
Storm, Philip A.
|
|
2017
|
|
3 |
p. 316-325
|
artikel
|
| 56 |
Fungal Secretion: The Next-Gen Target of Antifungal Agents?
|
Djordjevic, Julianne Teresa
|
|
2018
|
|
3 |
p. 233-235
|
artikel
|
| 57 |
Getting in on the action: New tools to see SARS-CoV-2 infect a cell
|
Hansen, Scott B.
|
|
|
|
3 |
p. 233-234
|
artikel
|
| 58 |
Hedgehog Signaling: From Basic Biology to Cancer Therapy
|
Wu, Fujia
|
|
2017
|
|
3 |
p. 252-280
|
artikel
|
| 59 |
HER-096 is a CDNF-derived brain-penetrating peptidomimetic that protects dopaminergic neurons in a mouse synucleinopathy model of Parkinson’s disease
|
Kulesskaya, Natalia
|
|
|
|
3 |
p. 593-606.e9
|
artikel
|
| 60 |
High-content phenotypic and pathway profiling to advance drug discovery in diseases of unmet need
|
Hughes, Rebecca E.
|
|
|
|
3 |
p. 338-355
|
artikel
|
| 61 |
HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers
|
Mo, Xiulei
|
|
2019
|
|
3 |
p. 331-339.e3
|
artikel
|
| 62 |
Human iPSC modeling of heart disease for drug development
|
Hnatiuk, Anna P.
|
|
|
|
3 |
p. 271-282
|
artikel
|
| 63 |
Hunting Cells for Gentle Liberation
|
Mayer, Günter
|
|
|
|
3 |
p. 257-258
|
artikel
|
| 64 |
Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells
|
Beyer, Mandy
|
|
|
|
3 |
p. 398-411.e4
|
artikel
|
| 65 |
Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition
|
McFadden, William M.
|
|
|
|
3 |
p. 477-486.e7
|
artikel
|
| 66 |
Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism
|
Miret-Casals, Laia
|
|
2018
|
|
3 |
p. 268-278.e4
|
artikel
|
| 67 |
Identification of Pax protein inhibitors that suppress target gene expression and cancer cell proliferation
|
Bradford, Shayna T.J.
|
|
|
|
3 |
p. 412-422.e4
|
artikel
|
| 68 |
Inhibiting GLUTtony in cancer
|
Chang, Sarah M.
|
|
|
|
3 |
p. 353-355
|
artikel
|
| 69 |
Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome
|
Okondo, Marian C.
|
|
2018
|
|
3 |
p. 262-267.e5
|
artikel
|
| 70 |
Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors
|
Olszewski, Kellen
|
|
|
|
3 |
p. 423-435.e10
|
artikel
|
| 71 |
In This Issue
|
|
|
2016
|
|
3 |
p. v-vi
nvt p.
|
artikel
|
| 72 |
Lipids Shape the Electron Acceptor-Binding Site of the Peripheral Membrane Protein Dihydroorotate Dehydrogenase
|
Costeira-Paulo, Joana
|
|
2018
|
|
3 |
p. 309-317.e4
|
artikel
|
| 73 |
Lipoprotein Signal Peptidase Inhibitors with Antibiotic Properties Identified through Design of a Robust In Vitro HT Platform
|
Kitamura, Seiya
|
|
2018
|
|
3 |
p. 301-308.e12
|
artikel
|
| 74 |
Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone
|
Singh, Jay K.
|
|
|
|
3 |
p. 292-305.e6
|
artikel
|
| 75 |
Mapping New Residents of the Mitochondrial Nucleoid
|
Trinkle-Mulcahy, Laura
|
|
2017
|
|
3 |
p. 250-251
|
artikel
|
| 76 |
Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I
|
Jain, Shashi
|
|
|
|
3 |
p. 436-450.e15
|
artikel
|
| 77 |
Metabolomics Reveals that Dietary Xenoestrogens Alter Cellular Metabolism Induced by Palbociclib/Letrozole Combination Cancer Therapy
|
Warth, Benedikt
|
|
2018
|
|
3 |
p. 291-300.e3
|
artikel
|
| 78 |
Morphological profiling of small molecules
|
Ziegler, Slava
|
|
|
|
3 |
p. 300-319
|
artikel
|
| 79 |
NAT8L mRNA oxidation is linked to neurodegeneration in multiple sclerosis
|
Kharel, Prakash
|
|
|
|
3 |
p. 308-320.e5
|
artikel
|
| 80 |
New Spins on Old Drugs: Enhancing Activity of Antifungals
|
Alspaugh, J. Andrew
|
|
|
|
3 |
p. 255-256
|
artikel
|
| 81 |
Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors
|
Smith, Christina E.
|
|
2017
|
|
3 |
p. 281-292
|
artikel
|
| 82 |
Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite
|
Hánová, Iva
|
|
2018
|
|
3 |
p. 318-329.e4
|
artikel
|
| 83 |
Nuisance compounds in cellular assays
|
Dahlin, Jayme L.
|
|
|
|
3 |
p. 356-370
|
artikel
|
| 84 |
One-pot trimodal mapping of unmethylated, hydroxymethylated, and open chromatin sites unveils distinctive 5hmC roles at dynamic chromatin loci
|
Skardžiūtė, Kotryna
|
|
|
|
3 |
p. 607-621.e9
|
artikel
|
| 85 |
Optogenetic Delineation of Receptor Tyrosine Kinase Subcircuits in PC12 Cell Differentiation
|
Khamo, John S.
|
|
2019
|
|
3 |
p. 400-410.e3
|
artikel
|
| 86 |
Our Advisors, Our Ambassadors, Our Editorial Board Members
|
Kostic, Milka
|
|
2016
|
|
3 |
p. 311-312
2 p.
|
artikel
|
| 87 |
Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2
|
Caplan, Tavia
|
|
|
|
3 |
p. 269-282.e5
|
artikel
|
| 88 |
Phenotypic approaches to small-molecule discovery in chemical biology
|
Wagner, Bridget K.
|
|
|
|
3 |
p. 245
|
artikel
|
| 89 |
Phenotypic screening with target identification and validation in the discovery and development of E3 ligase modulators
|
Ege, Nil
|
|
|
|
3 |
p. 283-299
|
artikel
|
| 90 |
Phenotypic technologies in stem cell biology
|
Vandana, J. Jeya
|
|
|
|
3 |
p. 257-270
|
artikel
|
| 91 |
Photoaffinity labeling coupled with proteomics identify PDI-ADAM17 module is targeted by (−)-vinigrol to induce TNFR1 shedding and ameliorate rheumatoid arthritis in mice
|
Zhu, Yinhua
|
|
|
|
3 |
p. 452-464.e10
|
artikel
|
| 92 |
Plasmodium PK9 Inhibitors Promote Growth of Liver-Stage Parasites
|
Raphemot, Rene
|
|
2019
|
|
3 |
p. 411-419.e7
|
artikel
|
| 93 |
Posttranslational Peptide-Modification Enzymes in Action: Key Roles for Leaders and Glutamate
|
Montalbán-López, Manuel
|
|
2016
|
|
3 |
p. 318-319
2 p.
|
artikel
|
| 94 |
Potent and Selective EphA4 Agonists for the Treatment of ALS
|
Wu, Bainan
|
|
2017
|
|
3 |
p. 293-305
|
artikel
|
| 95 |
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells
|
Tumber, Anthony
|
|
2017
|
|
3 |
p. 371-380
|
artikel
|
| 96 |
Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
|
Peng, Qianni
|
|
|
|
3 |
p. 550-564.e9
|
artikel
|
| 97 |
Proteasome Inhibition in Multiple Myeloma: Head-to-Head Comparison of Currently Available Proteasome Inhibitors
|
Besse, Andrej
|
|
2019
|
|
3 |
p. 340-351.e3
|
artikel
|
| 98 |
Proteomics from compartment-specific APEX2 labeling in Mycobacterium tuberculosis reveals Type VII secretion substrates in the cell wall
|
Jaisinghani, Neetika
|
|
|
|
3 |
p. 523-533.e4
|
artikel
|
| 99 |
Proximity Biotinylation as a Method for Mapping Proteins Associated with mtDNA in Living Cells
|
Han, Shuo
|
|
2017
|
|
3 |
p. 404-414
|
artikel
|
| 100 |
Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth
|
Sun, Le
|
|
|
|
3 |
p. 373-385.e6
|
artikel
|
| 101 |
Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides
|
Jongkees, Seino A.K.
|
|
2017
|
|
3 |
p. 381-390
|
artikel
|
| 102 |
RecA Inhibitors Potentiate Antibiotic Activity and Block Evolution of Antibiotic Resistance
|
Alam, Md Kausar
|
|
2016
|
|
3 |
p. 381-391
11 p.
|
artikel
|
| 103 |
Recent advances in identifying protein targets in drug discovery
|
Ha, Jaeyoung
|
|
|
|
3 |
p. 394-423
|
artikel
|
| 104 |
Re-defining synthetic lethality by phenotypic profiling for precision oncology
|
Akimov, Yevhen
|
|
|
|
3 |
p. 246-256
|
artikel
|
| 105 |
Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells
|
Kisty, Eleni A.
|
|
|
|
3 |
p. 321-336.e6
|
artikel
|
| 106 |
Reimagining dots and dashes: Visualizing structure and function of organelles for high-content imaging analysis
|
Chin, Marcus Y.
|
|
|
|
3 |
p. 320-337
|
artikel
|
| 107 |
Robust Prediction of Resistance to Trimethoprim in Staphylococcus aureus
|
Fowler, Philip W.
|
|
2018
|
|
3 |
p. 339-349.e4
|
artikel
|
| 108 |
ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD+-Mediated Epithelial-Mesenchymal Transition
|
Wang, Weixuan
|
|
2018
|
|
3 |
p. 255-261.e4
|
artikel
|
| 109 |
Saturated Fatty Acids, MUFAs and PUFAs Regulate Ferroptosis
|
Das, Undurti N.
|
|
2019
|
|
3 |
p. 309-311
|
artikel
|
| 110 |
Selective and brain-penetrant HCN1 inhibitors reveal links between synaptic integration, cortical function, and working memory
|
Harde, Eva
|
|
|
|
3 |
p. 577-592.e23
|
artikel
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