| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
A Bitter Tale of Sweet Synergy
|
Munger, Steven D.
|
|
2017
|
|
10 |
p. 1191-1192
2 p.
|
artikel
|
| 2 |
Acid-Tolerant Reversibly Switchable Green Fluorescent Protein for Super-resolution Imaging under Acidic Conditions
|
Shinoda, Hajime
|
|
2019
|
|
10 |
p. 1469-1479.e6
|
artikel
|
| 3 |
A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials
|
Gayvert, Kaitlyn M.
|
|
2016
|
|
10 |
p. 1294-1301
8 p.
|
artikel
|
| 4 |
Adding Lyso-Lipids to Arachidonate Metabolism Sets the Stage for New Biology
|
Shayman, James A.
|
|
2016
|
|
10 |
p. 1175-1176
2 p.
|
artikel
|
| 5 |
A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery
|
McMillan, Elizabeth A.
|
|
2019
|
|
10 |
p. 1380-1392.e6
|
artikel
|
| 6 |
A Glycoengineered Enzyme with Multiple Mannose-6-Phosphates Is Internalized into Diseased Cells to Restore Its Activity in Lysosomes
|
Hyun, Ji Young
|
|
2018
|
|
10 |
p. 1255-1267.e8
|
artikel
|
| 7 |
A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN
|
Weber, Aurelia
|
|
2017
|
|
10 |
p. 1299-1313.e7
1.3129998702E10 p.
|
artikel
|
| 8 |
A Link between Linearmycin Biosynthesis and Extracellular Vesicle Genesis Connects Specialized Metabolism and Bacterial Membrane Physiology
|
Hoefler, B. Christopher
|
|
2017
|
|
10 |
p. 1238-1249.e7
1.2489998763E10 p.
|
artikel
|
| 9 |
Analysis of the RNA Binding Specificity Landscape of C5 Protein Reveals Structure and Sequence Preferences that Direct RNase P Specificity
|
Lin, Hsuan-Chun
|
|
2016
|
|
10 |
p. 1271-1281
11 p.
|
artikel
|
| 10 |
A new chink in cancer’s armor: Unleashing cell death by selective PP5 inhibition
|
van Oosten-Hawle, Patricija
|
|
|
|
10 |
p. 1186-1188
|
artikel
|
| 11 |
A propeptide-based biosensor for the selective detection of Vibrio cholerae using an environment-sensitive fluorophore
|
DeColli, Alicia A.
|
|
|
|
10 |
p. 1505-1516.e7
|
artikel
|
| 12 |
A Split-Abl Kinase for Direct Activation in Cells
|
Diaz, Juan E.
|
|
2017
|
|
10 |
p. 1250-1258.e4
1.2578751E7 p.
|
artikel
|
| 13 |
A synthetic diterpene analogue inhibits mycobacterial persistence and biofilm formation by targeting (p)ppGpp synthetases
|
Tkachenko, Alexander G.
|
|
|
|
10 |
p. 1420-1432.e9
|
artikel
|
| 14 |
A transcriptional relationship with a natural product disrupts mitochondrial biogenesis
|
Wright, Aaron T.
|
|
|
|
10 |
p. 1392-1393
|
artikel
|
| 15 |
Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase
|
Schulze, Jörg O.
|
|
2016
|
|
10 |
p. 1193-1205
13 p.
|
artikel
|
| 16 |
Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide
|
Vasavda, Chirag
|
|
2019
|
|
10 |
p. 1450-1460.e7
|
artikel
|
| 17 |
Biomimetic Thioesters as Probes for Enzymatic Assembly Lines: Synthesis, Applications, and Challenges
|
Franke, Jakob
|
|
2016
|
|
10 |
p. 1179-1192
14 p.
|
artikel
|
| 18 |
Blends of Non-caloric Sweeteners Saccharin and Cyclamate Show Reduced Off-Taste due to TAS2R Bitter Receptor Inhibition
|
Behrens, Maik
|
|
2017
|
|
10 |
p. 1199-1204.e2
119202 p.
|
artikel
|
| 19 |
Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities
|
Schröder, Martin
|
|
|
|
10 |
p. 1285-1295.e4
|
artikel
|
| 20 |
Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer
|
Ahanin, Elham F.
|
|
|
|
10 |
p. 1223-1234.e12
|
artikel
|
| 21 |
Cell Chemical Biology announces changes to the editorial team
|
Dey, Mishtu
|
|
|
|
10 |
p. 1389
|
artikel
|
| 22 |
Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing
|
Liu, Yan
|
|
|
|
10 |
p. 1229-1240.e4
|
artikel
|
| 23 |
Chemical Induction of Aminoglycoside Uptake Overcomes Antibiotic Tolerance and Resistance in Staphylococcus aureus
|
Radlinski, Lauren C.
|
|
2019
|
|
10 |
p. 1355-1364.e4
|
artikel
|
| 24 |
Chemo-proteomics exploration of HDAC degradability by small molecule degraders
|
Xiong, Yuan
|
|
|
|
10 |
p. 1514-1527.e4
|
artikel
|
| 25 |
CLK2 and CLK4 are regulators of DNA damage-induced NF-κB targeted by novel small molecule inhibitors
|
Mucka, Patrick
|
|
|
|
10 |
p. 1303-1312.e3
|
artikel
|
| 26 |
Compartmentalized cAMP Generation by Engineered Photoactivated Adenylyl Cyclases
|
O'Banion, Colin P.
|
|
2019
|
|
10 |
p. 1393-1406.e7
|
artikel
|
| 27 |
Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I
|
Amatuni, Alexander
|
|
|
|
10 |
p. 1318-1326.e18
|
artikel
|
| 28 |
Conformation Selective Antibody Enables Genome Profiling and Leads to Discovery of Parallel G-Quadruplex in Human Telomeres
|
Liu, Hui-Yun
|
|
2016
|
|
10 |
p. 1261-1270
10 p.
|
artikel
|
| 29 |
Conquering Radicals with a Sense of Humor
|
Otterbein, Leo E.
|
|
2019
|
|
10 |
p. 1335-1337
|
artikel
|
| 30 |
Context-dependent regulation of ferroptosis sensitivity
|
Magtanong, Leslie
|
|
|
|
10 |
p. 1568
|
artikel
|
| 31 |
Customizing Functionalized Cofactor Mimics to Study the Human Pyridoxal 5′-Phosphate-Binding Proteome
|
Fux, Anja
|
|
2019
|
|
10 |
p. 1461-1468.e7
|
artikel
|
| 32 |
Cutting Choline with Radical Scissors
|
Broderick, Joan B.
|
|
2016
|
|
10 |
p. 1173-1174
2 p.
|
artikel
|
| 33 |
Cyclooxygenase-2 Mediated Oxidation of 2-Arachidonoyl-Lysophospholipids Identifies Unknown Lipid Signaling Pathways
|
Liu, Xinping
|
|
2016
|
|
10 |
p. 1217-1227
11 p.
|
artikel
|
| 34 |
CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism
|
Cho, Hyelim
|
|
|
|
10 |
p. 1407-1419.e6
|
artikel
|
| 35 |
Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to inverse agonism
|
Kwon, Yonghoon
|
|
|
|
10 |
p. 1532-1540.e5
|
artikel
|
| 36 |
Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7
|
Lamb, Kelsey N.
|
|
2019
|
|
10 |
p. 1365-1379.e22
|
artikel
|
| 37 |
Discovery of a covalent inhibitor of heat shock protein 90 with antitumor activity that blocks the co-chaperone binding via C-terminal modification
|
Li, Li
|
|
|
|
10 |
p. 1446-1459.e6
|
artikel
|
| 38 |
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer
|
Sharma, Shikhar
|
|
|
|
10 |
p. 1191-1210.e20
|
artikel
|
| 39 |
Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors
|
Rinis, Natalia
|
|
2018
|
|
10 |
p. 1231-1241.e4
|
artikel
|
| 40 |
Endogenous anti-tumorigenic nitro-fatty acids inhibit the ubiquitin-proteasome system by directly targeting the 26S proteasome
|
Brat, Camilla
|
|
|
|
10 |
p. 1277-1294.e12
|
artikel
|
| 41 |
Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactions
|
Willems, Sabine
|
|
|
|
10 |
p. 1489-1500.e8
|
artikel
|
| 42 |
Endoplasmic Reticulum Proteostasis Influences the Oligomeric State of an Amyloidogenic Protein Secreted from Mammalian Cells
|
Chen, John J.
|
|
2016
|
|
10 |
p. 1282-1293
12 p.
|
artikel
|
| 43 |
Evolution of kinase polypharmacology across HSP90 drug discovery
|
Antolin, Albert A.
|
|
|
|
10 |
p. 1433-1445.e3
|
artikel
|
| 44 |
Exploring the target scope of KEAP1 E3 ligase-based PROTACs
|
Du, Guangyan
|
|
|
|
10 |
p. 1470-1481.e31
|
artikel
|
| 45 |
Fishing for a balance: Toward promyelinating drug discovery
|
Collins, Hannah Y.
|
|
|
|
10 |
p. 1467-1469
|
artikel
|
| 46 |
HATS off to KAT6A/B inhibitors: A new way to target estrogen-receptor-positive breast cancer
|
Jeselsohn, Rinath
|
|
|
|
10 |
p. 1183-1185
|
artikel
|
| 47 |
Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria
|
Guo, Zhijun
|
|
2017
|
|
10 |
p. 1259-1275.e6
1.274998742E9 p.
|
artikel
|
| 48 |
Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria
|
Guo, Zhijun
|
|
2017
|
|
10 |
p. 1314-
1 p.
|
artikel
|
| 49 |
High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface
|
Datta, Suprama
|
|
|
|
10 |
p. 1313-1322.e7
|
artikel
|
| 50 |
Histone Demethylase LSD1 Promotes Adipocyte Differentiation through Repressing Wnt Signaling
|
Chen, Yan
|
|
2016
|
|
10 |
p. 1228-1240
13 p.
|
artikel
|
| 51 |
Humanized zebrafish as a tractable tool for in vivo evaluation of pro-myelinating drugs
|
Häberlein, Felix
|
|
|
|
10 |
p. 1541-1555.e7
|
artikel
|
| 52 |
Hydroxyhomocitrulline Is a Collagen-Specific Carbamylation Mark that Affects Cross-link Formation
|
Taga, Yuki
|
|
2017
|
|
10 |
p. 1276-1284.e3
1.282725E6 p.
|
artikel
|
| 53 |
Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3
|
Röth, Sascha
|
|
|
|
10 |
p. 1261-1276.e7
|
artikel
|
| 54 |
Inhibition of a lower potency target drives the anticancer activity of a clinical p38 inhibitor
|
Bhattacharjee, Debanjan
|
|
|
|
10 |
p. 1211-1222.e5
|
artikel
|
| 55 |
In This Issue
|
|
|
2016
|
|
10 |
p. vii-ix
nvt p.
|
artikel
|
| 56 |
In vivo bioluminescence imaging of granzyme B activity in tumor response to cancer immunotherapy
|
Chen, Min
|
|
|
|
10 |
p. 1556-1567.e6
|
artikel
|
| 57 |
Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease
|
Telling, Neil D.
|
|
2017
|
|
10 |
p. 1205-1215.e3
1.213796E6 p.
|
artikel
|
| 58 |
Linkage-Specific Detection and Metabolism of Human Milk Oligosaccharides in Escherichia coli
|
Enam, Fatima
|
|
2018
|
|
10 |
p. 1292-1303.e4
|
artikel
|
| 59 |
Localization matters in targeted protein degradation
|
Shah, Varun Jayeshkumar
|
|
|
|
10 |
p. 1465-1466
|
artikel
|
| 60 |
Mechanism of Cell Penetration by Permeabilization of Late Endosomes: Interplay between a Multivalent TAT Peptide and Bis(monoacylglycero)phosphate
|
Brock, Dakota J.
|
|
|
|
10 |
p. 1296-1307.e5
|
artikel
|
| 61 |
Mechanistic Details of Early Steps in Coenzyme Q Biosynthesis Pathway in Yeast
|
Payet, Laurie-Anne
|
|
2016
|
|
10 |
p. 1241-1250
10 p.
|
artikel
|
| 62 |
Membrane-Active Rhamnolipids Overcome Aminoglycoside Resistance
|
Yarlagadda, Venkateswarlu
|
|
2019
|
|
10 |
p. 1333-1334
|
artikel
|
| 63 |
Mimicry of a Non-ribosomally Produced Antimicrobial, Brevicidine, by Ribosomal Synthesis and Post-translational Modification
|
Zhao, Xinghong
|
|
|
|
10 |
p. 1262-1271.e4
|
artikel
|
| 64 |
Mitochondrial Ferredoxin Determines Vulnerability of Cells to Copper Excess
|
Vallières, Cindy
|
|
2017
|
|
10 |
p. 1228-1237.e3
1.235773E6 p.
|
artikel
|
| 65 |
MitoNeoD: A Mitochondria-Targeted Superoxide Probe
|
Shchepinova, Maria M.
|
|
2017
|
|
10 |
p. 1285-1298.e12
1.297999999998716E15 p.
|
artikel
|
| 66 |
Molecular Basis of C–N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase
|
Bodea, Smaranda
|
|
2016
|
|
10 |
p. 1206-1216
11 p.
|
artikel
|
| 67 |
Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies
|
Soave, Mark
|
|
|
|
10 |
p. 1250-1261.e5
|
artikel
|
| 68 |
More than One Way to Skin a Catalyst
|
Michnick, Stephen W.
|
|
2017
|
|
10 |
p. 1196-1197
2 p.
|
artikel
|
| 69 |
Mutant-Specific Targeting of Ras G12C Activity by Covalently Reacting Small Molecules
|
Goody, Roger S.
|
|
2019
|
|
10 |
p. 1338-1348
|
artikel
|
| 70 |
Nanoscale Imaging Reveals Big Role for Iron in Alzheimer’s Disease
|
Ayton, Scott
|
|
2017
|
|
10 |
p. 1192-1194
3 p.
|
artikel
|
| 71 |
Native mass spectrometry and gas-phase fragmentation provide rapid and in-depth topological characterization of a PROTAC ternary complex
|
Song, Jong Hee
|
|
|
|
10 |
p. 1528-1538.e4
|
artikel
|
| 72 |
Neutralization of the Positive Charges on Histone Tails by RNA Promotes an Open Chromatin Structure
|
Dueva, Rositsa
|
|
2019
|
|
10 |
p. 1436-1449.e5
|
artikel
|
| 73 |
Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation
|
Liu, Pengfei
|
|
2019
|
|
10 |
p. 1427-1435.e5
|
artikel
|
| 74 |
Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design
|
Tran, Brandon
|
|
|
|
10 |
p. 1241-1249.e4
|
artikel
|
| 75 |
Peripherally active dextromethorphan derivatives lower blood glucose levels by targeting pancreatic islets
|
Scholz, Okka
|
|
|
|
10 |
p. 1474-1488.e7
|
artikel
|
| 76 |
Protein Chemistry Looking Ahead: 8th Chemical Protein Synthesis Meeting 16-19 June 2019, Berlin, Germany
|
Bello, Claudia
|
|
2019
|
|
10 |
p. 1349-1354
|
artikel
|
| 77 |
RAF Inhibitors, Fishing Bacterial Transporters Out of Metagenomes, and Yeast-Based, Industrial Scale Production of Isoprenoids
|
Kostic, Milka
|
|
2016
|
|
10 |
p. 1171-1172
2 p.
|
artikel
|
| 78 |
Real-Time Ligand Binding of Fluorescent VEGF-A Isoforms that Discriminate between VEGFR2 and NRP1 in Living Cells
|
Peach, Chloe J.
|
|
2018
|
|
10 |
p. 1208-1218.e5
|
artikel
|
| 79 |
Resurrecting the Bacterial Tyrosyl-tRNA Synthetase/tRNA Pair for Expanding the Genetic Code of Both E. coli and Eukaryotes
|
Italia, James S.
|
|
2018
|
|
10 |
p. 1304-1312.e5
|
artikel
|
| 80 |
RNA Binding: Getting Specific about Specificity
|
Ferré-D’Amaré, Adrian R.
|
|
2016
|
|
10 |
p. 1177-1178
2 p.
|
artikel
|
| 81 |
Role of Thiol Reactivity for Targeting Mutant p53
|
Zhang, Qiang
|
|
2018
|
|
10 |
p. 1219-1230.e3
|
artikel
|
| 82 |
Selective Inhibition of Sialic Acid-Based Molecular Mimicry in Haemophilus influenzae Abrogates Serum Resistance
|
Heise, Torben
|
|
2018
|
|
10 |
p. 1279-1285.e8
|
artikel
|
| 83 |
Site-Specific Incorporation of Genetically Encoded Photo-Crosslinkers Locates the Heteromeric Interface of a GPCR Complex in Living Cells
|
Shah, Urjita H.
|
|
|
|
10 |
p. 1308-1317.e4
|
artikel
|
| 84 |
Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage
|
Venkannagari, Harikanth
|
|
2016
|
|
10 |
p. 1251-1260
10 p.
|
artikel
|
| 85 |
Small molecule targeting of transcription-replication conflict for selective chemotherapy
|
Gu, Long
|
|
|
|
10 |
p. 1235-1247.e6
|
artikel
|
| 86 |
Small-Molecule TLR8 Antagonists via Structure-Based Rational Design
|
Hu, Zhenyi
|
|
2018
|
|
10 |
p. 1286-1291.e3
|
artikel
|
| 87 |
Split-miniSOG for Spatially Detecting Intracellular Protein-Protein Interactions by Correlated Light and Electron Microscopy
|
Boassa, Daniela
|
|
2019
|
|
10 |
p. 1407-1416.e5
|
artikel
|
| 88 |
Subcellular Hsp70 Inhibitors Promote Cancer Cell Death via Different Mechanisms
|
Park, Sang-Hyun
|
|
2018
|
|
10 |
p. 1242-1254.e8
|
artikel
|
| 89 |
Substrate-dependent interaction of SPOP and RACK1 aggravates cardiac fibrosis following myocardial infarction
|
Yang, Wanqi
|
|
|
|
10 |
p. 1248-1260.e4
|
artikel
|
| 90 |
Succinylation of a KEAP1 sensor lysine promotes NRF2 activation
|
Ibrahim, Lara
|
|
|
|
10 |
p. 1295-1302.e4
|
artikel
|
| 91 |
SUMO wrestling cancer stem cells
|
Liu, Qiang
|
|
|
|
10 |
p. 1390-1392
|
artikel
|
| 92 |
Synthetic Immunotherapeutics against Gram-negative Pathogens
|
Feigman, Mary Sabulski
|
|
2018
|
|
10 |
p. 1185-1194.e5
|
artikel
|
| 93 |
Systematic Identification of Pharmacological Targets from Small-Molecule Phenotypic Screens
|
Liu, Xueping
|
|
2016
|
|
10 |
p. 1302-1313
12 p.
|
artikel
|
| 94 |
Targeting allostery in the Dynein motor domain with small molecule inhibitors
|
Santarossa, Cristina C.
|
|
|
|
10 |
p. 1460-1473.e15
|
artikel
|
| 95 |
Targeting Pim Kinases and DAPK3 to Control Hypertension
|
Carlson, David A.
|
|
2018
|
|
10 |
p. 1195-1207.e32
|
artikel
|
| 96 |
Targeting Primary Ciliogenesis with Small-Molecule Inhibitors
|
Guen, Vincent J.
|
|
|
|
10 |
p. 1224-1228
|
artikel
|
| 97 |
Targeting selective E3 ligase for healing cardiac fibrosis
|
Yang, Guangdong
|
|
|
|
10 |
p. 1188-1190
|
artikel
|
| 98 |
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics
|
Benoit, Yannick D.
|
|
|
|
10 |
p. 1394-1406.e10
|
artikel
|
| 99 |
Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization
|
Liu, Yue
|
|
|
|
10 |
p. 1517-1531.e7
|
artikel
|
| 100 |
Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling
|
Jiang, Chenxiao
|
|
2019
|
|
10 |
p. 1417-1426.e5
|
artikel
|
| 101 |
Target protein localization and its impact on PROTAC-mediated degradation
|
Simpson, Luke M.
|
|
|
|
10 |
p. 1482-1504.e7
|
artikel
|
| 102 |
The Bump-and-Hole Tactic: Expanding the Scope of Chemical Genetics
|
Islam, Kabirul
|
|
2018
|
|
10 |
p. 1171-1184
|
artikel
|
| 103 |
The High Genetic Barrier of EFdA/MK-8591 Stems from Strong Interactions with the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase
|
Takamatsu, Yuki
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