nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
Accurate top protein variant discovery via low-N pick-and-validate machine learning
|
Chu, Hoi Yee |
|
|
|
2 |
p. 193-203.e6 |
artikel |
2 |
A Computational Framework for Genome-wide Characterization of the Human Disease Landscape
|
Lee, Young-suk |
|
2019 |
|
2 |
p. 152-162.e6 |
artikel |
3 |
A continuous epistasis model for predicting growth rate given combinatorial variation in gene expression and environment
|
Otto, Ryan M. |
|
|
|
2 |
p. 134-148.e7 |
artikel |
4 |
A Dynamic Model of Immune Responses to Antigen Presentation Predicts Different Regions of Tumor or Pathogen Elimination
|
Sontag, Eduardo D. |
|
2017 |
|
2 |
p. 231-241.e11 |
artikel |
5 |
A Global Screen for Assembly State Changes of the Mitotic Proteome by SEC-SWATH-MS
|
Heusel, Moritz |
|
|
|
2 |
p. 133-155.e6 |
artikel |
6 |
Allele-specific genomic data elucidate the role of somatic gain and copy-number neutral loss of heterozygosity in cancer
|
Ciani, Yari |
|
|
|
2 |
p. 183-193.e7 |
artikel |
7 |
All’s Well That Scales Well
|
Mak, H. Craig |
|
2016 |
|
2 |
p. 59- 1 p. |
artikel |
8 |
Antithetic Integral Feedback Ensures Robust Perfect Adaptation in Noisy Biomolecular Networks
|
Briat, Corentin |
|
2016 |
|
2 |
p. 133- 1 p. |
artikel |
9 |
Assessing Inequality in Transcriptomic Data
|
Jiang, Lan |
|
|
|
2 |
p. 149-150 |
artikel |
10 |
Asymmetric Damage Segregation Constitutes an Emergent Population-Level Stress Response
|
Vedel, Søren |
|
2016 |
|
2 |
p. 187-198 12 p. |
artikel |
11 |
A synthetic gene circuit for imaging-free detection of signaling pulses
|
Ravindran, Pavithran T. |
|
|
|
2 |
p. 131-142.e13 |
artikel |
12 |
A top variant identification pipeline for protein engineering
|
Chen, Hui |
|
|
|
2 |
p. 105-106 |
artikel |
13 |
A Two-Layer Gene Circuit for Decoupling Cell Growth from Metabolite Production
|
Lo, Tat-Ming |
|
2016 |
|
2 |
p. 133-143 11 p. |
artikel |
14 |
Automated Design of Synthetic Cell Classifier Circuits Using a Two-Step Optimization Strategy
|
Mohammadi, Pejman |
|
2017 |
|
2 |
p. 207-218.e14 |
artikel |
15 |
Benchmarking Computational Doublet-Detection Methods for Single-Cell RNA Sequencing Data
|
Xi, Nan Miles |
|
|
|
2 |
p. 176-194.e6 |
artikel |
16 |
Best Practices for Making Reproducible Biochemical Models
|
Porubsky, Veronica L. |
|
|
|
2 |
p. 109-120 |
artikel |
17 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain
|
Pourhaghighi, Reza |
|
|
|
2 |
p. 208 |
artikel |
18 |
Canalization of C. elegans Vulva Induction against Anatomical Variability
|
Huelsz-Prince, Guizela |
|
2017 |
|
2 |
p. 219-230.e6 |
artikel |
19 |
Capturing a Long Look at Our Genetic Library
|
Lagarde, Julien |
|
|
|
2 |
p. 153-155 |
artikel |
20 |
Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis
|
Plaisier, Christopher L. |
|
2016 |
|
2 |
p. 172-186 15 p. |
artikel |
21 |
CellBox: Interpretable Machine Learning for Perturbation Biology with Application to the Design of Cancer Combination Therapy
|
Yuan, Bo |
|
|
|
2 |
p. 128-140.e4 |
artikel |
22 |
Cellular Advantages to Signaling in a Digital World
|
Mancuso, Christopher P. |
|
2016 |
|
2 |
p. 114-115 2 p. |
artikel |
23 |
Clonally heritable gene expression imparts a layer of diversity within cell types
|
Mold, Jeff E. |
|
|
|
2 |
p. 149-165.e10 |
artikel |
24 |
Community Assessment of the Predictability of Cancer Protein and Phosphoprotein Levels from Genomics and Transcriptomics
|
Yang, Mi |
|
|
|
2 |
p. 186-195.e9 |
artikel |
25 |
Compensatory Cell Movements Confer Robustness to Mechanical Deformation during Embryonic Development
|
Jelier, Rob |
|
2016 |
|
2 |
p. 160-171 12 p. |
artikel |
26 |
Comprehensive Analysis of Tissue-wide Gene Expression and Phenotype Data Reveals Tissues Affected in Rare Genetic Disorders
|
Feiglin, Ariel |
|
2017 |
|
2 |
p. 140-148.e2 14661 p. |
artikel |
27 |
Compression Generated by a 3D Supracellular Actomyosin Cortex Promotes Embryonic Stem Cell Colony Growth and Expression of Nanog and Oct4
|
Du, Jing |
|
2019 |
|
2 |
p. 214-220.e5 |
artikel |
28 |
Computationally Optimized SARS-CoV-2 MHC Class I and II Vaccine Formulations Predicted to Target Human Haplotype Distributions
|
Liu, Ge |
|
|
|
2 |
p. 131-144.e6 |
artikel |
29 |
Considering and Reconsidering Peer Review
|
Mak, H. Craig |
|
2017 |
|
2 |
p. 87- 1 p. |
artikel |
30 |
Continuous-Trait Probabilistic Model for Comparing Multi-species Functional Genomic Data
|
Yang, Yang |
|
|
|
2 |
p. 208-218.e11 |
artikel |
31 |
Controlling the human microbiome
|
Liu, Yang-Yu |
|
|
|
2 |
p. 135-159 |
artikel |
32 |
Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo
|
Codina, Adan |
|
2019 |
|
2 |
p. 136-151.e7 |
artikel |
33 |
Cross-Comparison of Human iPSC Motor Neuron Models of Familial and Sporadic ALS Reveals Early and Convergent Transcriptomic Disease Signatures
|
Ho, Ritchie |
|
|
|
2 |
p. 159-175.e9 |
artikel |
34 |
Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species
|
Stein-O’Brien, Genevieve L. |
|
|
|
2 |
p. 203 |
artikel |
35 |
Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States
|
Kim, Jong Wook |
|
2017 |
|
2 |
p. 105-118.e9 1.17999999896E11 p. |
artikel |
36 |
Deep Proteome Analysis Identifies Age-Related Processes in C. elegans
|
Narayan, Vikram |
|
2016 |
|
2 |
p. 144-159 16 p. |
artikel |
37 |
Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate
|
Corwin, Thomas |
|
2017 |
|
2 |
p. 128-139.e4 1.389873E6 p. |
artikel |
38 |
Design of Adjacent Transcriptional Regions to Tune Gene Expression and Facilitate Circuit Construction
|
Wu, Fuqing |
|
|
|
2 |
p. 206-215.e6 |
artikel |
39 |
Determination of the Gene Regulatory Network of a Genome-Reduced Bacterium Highlights Alternative Regulation Independent of Transcription Factors
|
Yus, Eva |
|
2019 |
|
2 |
p. 143-158.e13 |
artikel |
40 |
Differential Allele-Specific Expression Uncovers Breast Cancer Genes Dysregulated by Cis Noncoding Mutations
|
Przytycki, Pawel F. |
|
|
|
2 |
p. 193-203.e4 |
artikel |
41 |
Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling
|
Rukhlenko, Oleksii S. |
|
|
|
2 |
p. 161-179.e14 |
artikel |
42 |
Editorial Transparency
|
|
|
2017 |
|
2 |
p. 139 |
artikel |
43 |
Entropy-Scaling Search of Massive Biological Data
|
Yu, Y. William |
|
2015 |
|
2 |
p. 130-140 11 p. |
artikel |
44 |
Evaluation of Chen et al.: Overexpression of Protein Complexes and Aneuploidy
|
Amon, Angelika |
|
2019 |
|
2 |
p. 107-108 |
artikel |
45 |
Evaluation of Kuroda et al.: Insight into Yeast Isobutanol Tolerance with Advances Still Needed
|
Hittinger, Chris Todd |
|
|
|
2 |
p. 124 |
artikel |
46 |
Evaluation of Ravindran et al.: Real-time detection of signaling pulses in vivo: making cells monitor themselves
|
Garcia-Ojalvo, Jordi |
|
|
|
2 |
p. 105-106 |
artikel |
47 |
Even Noisy Responses Can Be Perfect If Integrated Properly
|
Doyle, John C. |
|
2016 |
|
2 |
p. 73-75 3 p. |
artikel |
48 |
Evolutionary Inference across Eukaryotes Identifies Specific Pressures Favoring Mitochondrial Gene Retention
|
Johnston, Iain G. |
|
2016 |
|
2 |
p. 101-111 11 p. |
artikel |
49 |
Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results
|
Riba, Andrea |
|
2017 |
|
2 |
p. 182-193.e4 |
artikel |
50 |
Fast, Quantitative and Variant Enabled Mapping of Peptides to Genomes
|
Schlaffner, Christoph N. |
|
2017 |
|
2 |
p. 152-156.e4 1.559849E6 p. |
artikel |
51 |
Finding the Optimal Tradeoffs
|
Mathew, Shibin |
|
2017 |
|
2 |
p. 149-151 |
artikel |
52 |
FLASHDeconv: Ultrafast, High-Quality Feature Deconvolution for Top-Down Proteomics
|
Jeong, Kyowon |
|
|
|
2 |
p. 213-218.e6 |
artikel |
53 |
From Yeast to Patients: The Audacity and Vision of Susan Lindquist
|
Khurana, Vikram |
|
2017 |
|
2 |
p. 147-148 |
artikel |
54 |
Fundamental Limits of Search
|
Kannan, Sreeram |
|
2015 |
|
2 |
p. 102-103 2 p. |
artikel |
55 |
GCN2 adapts protein synthesis to scavenging-dependent growth
|
Nofal, Michel |
|
|
|
2 |
p. 158-172.e9 |
artikel |
56 |
GeneGini: Assessment via the Gini Coefficient of Reference “Housekeeping” Genes and Diverse Human Transporter Expression Profiles
|
O'Hagan, Steve |
|
|
|
2 |
p. 230-244.e1 |
artikel |
57 |
Generalizable and Scalable Visualization of Single-Cell Data Using Neural Networks
|
Cho, Hyunghoon |
|
|
|
2 |
p. 185-191.e4 |
artikel |
58 |
Gene Regulatory Strategies that Decode the Duration of NFκB Dynamics Contribute to LPS- versus TNF-Specific Gene Expression
|
Sen, Supriya |
|
|
|
2 |
p. 169-182.e5 |
artikel |
59 |
Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways
|
Khurana, Vikram |
|
2017 |
|
2 |
p. 157-170.e14 |
artikel |
60 |
Genome-Scale Transcriptional Regulatory Network Models of Psychiatric and Neurodegenerative Disorders
|
Pearl, Jocelynn R. |
|
2019 |
|
2 |
p. 122-135.e7 |
artikel |
61 |
Genomic Recoding Broadly Obstructs the Propagation of Horizontally Transferred Genetic Elements
|
Ma, Natalie Jing |
|
2016 |
|
2 |
p. 199-207 9 p. |
artikel |
62 |
Growth-Optimized Aminoacyl-tRNA Synthetase Levels Prevent Maximal tRNA Charging
|
Parker, Darren J. |
|
|
|
2 |
p. 121-130.e6 |
artikel |
63 |
High-Throughput Affinity Measurements of Transcription Factor and DNA Mutations Reveal Affinity and Specificity Determinants
|
Aditham, Arjun K. |
|
|
|
2 |
p. 112-127.e11 |
artikel |
64 |
How Can Systems Biology Test Principles and Tools Using Immune Cells as a Model?
|
|
|
|
|
2 |
p. 146-148 |
artikel |
65 |
How Does Large-Scale Genomic Analysis Shape Our Understanding of COVID Variants in Real Time?
|
van Dorp, Lucy |
|
|
|
2 |
p. 109-111 |
artikel |
66 |
“How Do You Know?” The Answer Lies in Methods
|
Justman, Quincey |
|
|
|
2 |
p. 121 |
artikel |
67 |
How to Understand Systems
|
Mak, H. Craig |
|
2015 |
|
2 |
p. 99- 1 p. |
artikel |
68 |
How Will Kinetics and Thermodynamics Inform Our Future Efforts to Understand and Build Biological Systems?
|
|
|
2017 |
|
2 |
p. 144-146 |
artikel |
69 |
Hunting for Cis-Regulatory Elements in Proteins
|
Gibson, Toby J. |
|
2016 |
|
2 |
p. 68-70 3 p. |
artikel |
70 |
Inferring Regulatory Programs Governing Region Specificity of Neuroepithelial Stem Cells during Early Hindbrain and Spinal Cord Development
|
Chasman, Deborah |
|
2019 |
|
2 |
p. 167-186.e12 |
artikel |
71 |
Insights into the Mechanisms of Basal Coordination of Transcription Using a Genome-Reduced Bacterium
|
Junier, Ivan |
|
|
|
2 |
p. 227-229 |
artikel |
72 |
In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons
|
Chung, Chee Yeun |
|
2017 |
|
2 |
p. 242-250.e4 |
artikel |
73 |
Integrative Personal Omics Profiles during Periods of Weight Gain and Loss
|
Piening, Brian D. |
|
|
|
2 |
p. 157-170.e8 |
artikel |
74 |
In the Future, Data and Code Should Be FAIR
|
Justman, Quincey |
|
2019 |
|
2 |
p. 95 |
artikel |
75 |
In This Issue
|
|
|
2016 |
|
2 |
p. ix- 1 p. |
artikel |
76 |
In This Issue
|
|
|
2015 |
|
2 |
p. ix- 1 p. |
artikel |
77 |
Joint Analysis of Long and Short Reads Enables Accurate Estimates of Microbiome Complexity
|
Bankevich, Anton |
|
|
|
2 |
p. 192-200.e3 |
artikel |
78 |
Juicebox.js Provides a Cloud-Based Visualization System for Hi-C Data
|
Robinson, James T. |
|
|
|
2 |
p. 256-258.e1 |
artikel |
79 |
Keeping the Proportions of Protein Complex Components in Check
|
Taggart, James Christopher |
|
|
|
2 |
p. 125-132 |
artikel |
80 |
Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan
|
Baumgart, Mario |
|
2016 |
|
2 |
p. 122-132 11 p. |
artikel |
81 |
Mantis: A Fast, Small, and Exact Large-Scale Sequence-Search Index
|
Pandey, Prashant |
|
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|
2 |
p. 201-207.e4 |
artikel |
82 |
Mapping combinatorial expression perturbations to growth in Escherichia coli
|
McCain, J. Scott P. |
|
|
|
2 |
p. 106-108 |
artikel |
83 |
Maximum Entropy Framework for Predictive Inference of Cell Population Heterogeneity and Responses in Signaling Networks
|
Dixit, Purushottam D. |
|
|
|
2 |
p. 204-212.e8 |
artikel |
84 |
Merged Map of the Yeast Proteome
|
Schmidt, Alexander |
|
|
|
2 |
p. 150-152 |
artikel |
85 |
Metabolic models of human gut microbiota: Advances and challenges
|
Rios Garza, Daniel |
|
|
|
2 |
p. 109-121 |
artikel |
86 |
Modeling the Future
|
Mak, H. Craig |
|
2016 |
|
2 |
p. 109- 1 p. |
artikel |
87 |
Molecular and Functional Networks Linked to Sarcopenia Prevention by Caloric Restriction in Rhesus Monkeys
|
Rhoads, Timothy W. |
|
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|
2 |
p. 156-168.e5 |
artikel |
88 |
Molecular Time Sharing through Dynamic Pulsing in Single Cells
|
Park, Jin |
|
|
|
2 |
p. 216-229.e15 |
artikel |
89 |
Navigating the Cancer Transcriptome by Decoding Divergent Oncogenic States
|
Amin, Samirkumar B. |
|
2017 |
|
2 |
p. 90-92 3 p. |
artikel |
90 |
Network Architecture Predisposes an Enzyme to Either Pharmacologic or Genetic Targeting
|
Jensen, Karin J. |
|
2016 |
|
2 |
p. 112-121 10 p. |
artikel |
91 |
Optimal Regulatory Circuit Topologies for Fold-Change Detection
|
Adler, Miri |
|
2017 |
|
2 |
p. 171-181.e8 |
artikel |
92 |
Overdosage of Balanced Protein Complexes Reduces Proliferation Rate in Aneuploid Cells
|
Chen, Ying |
|
2019 |
|
2 |
p. 129-142.e5 |
artikel |
93 |
Parallelization and High-Performance Computing Enables Automated Statistical Inference of Multi-scale Models
|
Jagiella, Nick |
|
2017 |
|
2 |
p. 194-206.e9 |
artikel |
94 |
Perfect and Near-Perfect Adaptation in Cell Signaling
|
Ferrell Jr., James E. |
|
2016 |
|
2 |
p. 62-67 6 p. |
artikel |
95 |
Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma
|
Golkowski, Martin |
|
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|
2 |
p. 196-207.e7 |
artikel |
96 |
Phylogenetic Profiling for Probing the Modular Architecture of the Human Genome
|
Dey, Gautam |
|
2015 |
|
2 |
p. 106-115 10 p. |
artikel |
97 |
Pitfalls of genotyping microbial communities with rapidly growing genome collections
|
Zhao, Chunyu |
|
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|
2 |
p. 160-176.e3 |
artikel |
98 |
Positive Gradients
|
Mak, Craig |
|
2015 |
|
2 |
p. 174- 1 p. |
artikel |
99 |
Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids
|
D'Ippolito, Anthony M. |
|
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2 |
p. 146-160.e7 |
artikel |
100 |
Principles of Systems Biology, No. 2
|
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|
2016 |
|
2 |
p. 60-61 2 p. |
artikel |
101 |
Principles of Systems Biology, No. 20
|
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2017 |
|
2 |
p. 88-89 2 p. |
artikel |
102 |
Principles of Systems Biology, No. 8
|
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2016 |
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2 |
p. 110-113 4 p. |
artikel |
103 |
Principles of Systems Biology, No. 14
|
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2017 |
|
2 |
p. 140-143 |
artikel |
104 |
Principles of Systems Biology, No. 26
|
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2 |
p. 143-145 |
artikel |
105 |
Principles of Systems Biology, No. 31
|
Cho, Hyunghoon |
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2 |
p. 133-135 |
artikel |
106 |
Privacy-preserving genotype imputation with fully homomorphic encryption
|
Gürsoy, Gamze |
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2 |
p. 173-182.e3 |
artikel |
107 |
Protein Networks in Alzheimer’s Disease
|
Carlsen, Eva Meier |
|
2017 |
|
2 |
p. 153-155 |
artikel |
108 |
Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals
|
Hark, Timothy J. |
|
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2 |
p. 141-158.e9 |
artikel |
109 |
Quantification of Uncertainty in Peptide-MHC Binding Prediction Improves High-Affinity Peptide Selection for Therapeutic Design
|
Zeng, Haoyang |
|
2019 |
|
2 |
p. 159-166.e3 |
artikel |
110 |
Quantifying Drug Combination Synergy along Potency and Efficacy Axes
|
Meyer, Christian T. |
|
2019 |
|
2 |
p. 97-108.e16 |
artikel |
111 |
Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome
|
Wang, Tina |
|
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2 |
p. 176-185.e6 |
artikel |
112 |
Rare Cell Detection by Single-Cell RNA Sequencing as Guided by Single-Molecule RNA FISH
|
Torre, Eduardo |
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2 |
p. 171-179.e5 |
artikel |
113 |
RBM-MHC: A Semi-Supervised Machine-Learning Method for Sample-Specific Prediction of Antigen Presentation by HLA-I Alleles
|
Bravi, Barbara |
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2 |
p. 195-202.e9 |
artikel |
114 |
Remote-Controlled Mice
|
Anikeeva, Polina |
|
2015 |
|
2 |
p. 104-105 2 p. |
artikel |
115 |
Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
|
Jain, Naveen |
|
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2 |
p. 109-133.e10 |
artikel |
116 |
ROS and Oxidative Stress Are Elevated in Mitosis during Asynchronous Cell Cycle Progression and Are Exacerbated by Mitotic Arrest
|
Patterson, Jesse C. |
|
2019 |
|
2 |
p. 163-167.e2 |
artikel |
117 |
Science that Inspires
|
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2 |
p. 122-123 |
artikel |
118 |
Scikit-ribo Enables Accurate Estimation and Robust Modeling of Translation Dynamics at Codon Resolution
|
Fang, Han |
|
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2 |
p. 180-191.e4 |
artikel |
119 |
Semblance of Heterogeneity in Collective Cell Migration
|
Schumacher, Linus J. |
|
2017 |
|
2 |
p. 119-127.e1 1152 p. |
artikel |
120 |
Sensing the Right Time to Be Productive
|
Ceroni, Francesca |
|
2016 |
|
2 |
p. 116-117 2 p. |
artikel |
121 |
Signal Percolation within a Bacterial Community
|
Larkin, Joseph W. |
|
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2 |
p. 137-145.e3 |
artikel |
122 |
Simple visualization of submicroscopic protein clusters with a phase-separation-based fluorescent reporter
|
Mumford, Thomas R. |
|
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2 |
p. 166-179.e7 |
artikel |
123 |
Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity
|
Blecher-Gonen, Ronnie |
|
2019 |
|
2 |
p. 109-121.e6 |
artikel |
124 |
Single-cell colocalization analysis using a deep generative model
|
Kojima, Yasuhiro |
|
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2 |
p. 180-192.e7 |
artikel |
125 |
SingleCellNet: A Computational Tool to Classify Single Cell RNA-Seq Data Across Platforms and Across Species
|
Tan, Yuqi |
|
2019 |
|
2 |
p. 207-213.e2 |
artikel |
126 |
Spatial self-organization of metabolism in microbial systems: A matter of enzymes and chemicals
|
Dal Co, Alma |
|
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|
2 |
p. 98-108 |
artikel |
127 |
Statistical Binning for Barcoded Reads Improves Downstream Analyses
|
Shajii, Ariya |
|
|
|
2 |
p. 219-226.e5 |
artikel |
128 |
Stochastic Self-Assembly of ParB Proteins Builds the Bacterial DNA Segregation Apparatus
|
Sanchez, Aurore |
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2015 |
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Davies, Alexander E. |
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p. 161-175.e5 |
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Yeon, Ju Hun |
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2016 |
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Borland, David |
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p. 180-184.e4 |
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Reich, Michael |
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p. 183-192.e6 |
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Hamelin, David J. |
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p. 143-157.e3 |
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p. 187-206.e16 |
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p. 109-130.e6 |
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Hutchins, Andrew P. |
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Deveson, Ira W. |
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p. 245-255.e5 |
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