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                             155 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Accurate top protein variant discovery via low-N pick-and-validate machine learning Chu, Hoi Yee

2 p. 193-203.e6
artikel
2 A Computational Framework for Genome-wide Characterization of the Human Disease Landscape Lee, Young-suk
2019
2 p. 152-162.e6
artikel
3 A continuous epistasis model for predicting growth rate given combinatorial variation in gene expression and environment Otto, Ryan M.

2 p. 134-148.e7
artikel
4 A Dynamic Model of Immune Responses to Antigen Presentation Predicts Different Regions of Tumor or Pathogen Elimination Sontag, Eduardo D.
2017
2 p. 231-241.e11
artikel
5 A Global Screen for Assembly State Changes of the Mitotic Proteome by SEC-SWATH-MS Heusel, Moritz

2 p. 133-155.e6
artikel
6 Allele-specific genomic data elucidate the role of somatic gain and copy-number neutral loss of heterozygosity in cancer Ciani, Yari

2 p. 183-193.e7
artikel
7 All’s Well That Scales Well Mak, H. Craig
2016
2 p. 59-
1 p.
artikel
8 Antithetic Integral Feedback Ensures Robust Perfect Adaptation in Noisy Biomolecular Networks Briat, Corentin
2016
2 p. 133-
1 p.
artikel
9 Assessing Inequality in Transcriptomic Data Jiang, Lan

2 p. 149-150
artikel
10 Asymmetric Damage Segregation Constitutes an Emergent Population-Level Stress Response Vedel, Søren
2016
2 p. 187-198
12 p.
artikel
11 A synthetic gene circuit for imaging-free detection of signaling pulses Ravindran, Pavithran T.

2 p. 131-142.e13
artikel
12 A top variant identification pipeline for protein engineering Chen, Hui

2 p. 105-106
artikel
13 A Two-Layer Gene Circuit for Decoupling Cell Growth from Metabolite Production Lo, Tat-Ming
2016
2 p. 133-143
11 p.
artikel
14 Automated Design of Synthetic Cell Classifier Circuits Using a Two-Step Optimization Strategy Mohammadi, Pejman
2017
2 p. 207-218.e14
artikel
15 Benchmarking Computational Doublet-Detection Methods for Single-Cell RNA Sequencing Data Xi, Nan Miles

2 p. 176-194.e6
artikel
16 Best Practices for Making Reproducible Biochemical Models Porubsky, Veronica L.

2 p. 109-120
artikel
17 BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain Pourhaghighi, Reza

2 p. 208
artikel
18 Canalization of C. elegans Vulva Induction against Anatomical Variability Huelsz-Prince, Guizela
2017
2 p. 219-230.e6
artikel
19 Capturing a Long Look at Our Genetic Library Lagarde, Julien

2 p. 153-155
artikel
20 Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis Plaisier, Christopher L.
2016
2 p. 172-186
15 p.
artikel
21 CellBox: Interpretable Machine Learning for Perturbation Biology with Application to the Design of Cancer Combination Therapy Yuan, Bo

2 p. 128-140.e4
artikel
22 Cellular Advantages to Signaling in a Digital World Mancuso, Christopher P.
2016
2 p. 114-115
2 p.
artikel
23 Clonally heritable gene expression imparts a layer of diversity within cell types Mold, Jeff E.

2 p. 149-165.e10
artikel
24 Community Assessment of the Predictability of Cancer Protein and Phosphoprotein Levels from Genomics and Transcriptomics Yang, Mi

2 p. 186-195.e9
artikel
25 Compensatory Cell Movements Confer Robustness to Mechanical Deformation during Embryonic Development Jelier, Rob
2016
2 p. 160-171
12 p.
artikel
26 Comprehensive Analysis of Tissue-wide Gene Expression and Phenotype Data Reveals Tissues Affected in Rare Genetic Disorders Feiglin, Ariel
2017
2 p. 140-148.e2
14661 p.
artikel
27 Compression Generated by a 3D Supracellular Actomyosin Cortex Promotes Embryonic Stem Cell Colony Growth and Expression of Nanog and Oct4 Du, Jing
2019
2 p. 214-220.e5
artikel
28 Computationally Optimized SARS-CoV-2 MHC Class I and II Vaccine Formulations Predicted to Target Human Haplotype Distributions Liu, Ge

2 p. 131-144.e6
artikel
29 Considering and Reconsidering Peer Review Mak, H. Craig
2017
2 p. 87-
1 p.
artikel
30 Continuous-Trait Probabilistic Model for Comparing Multi-species Functional Genomic Data Yang, Yang

2 p. 208-218.e11
artikel
31 Controlling the human microbiome Liu, Yang-Yu

2 p. 135-159
artikel
32 Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo Codina, Adan
2019
2 p. 136-151.e7
artikel
33 Cross-Comparison of Human iPSC Motor Neuron Models of Familial and Sporadic ALS Reveals Early and Convergent Transcriptomic Disease Signatures Ho, Ritchie

2 p. 159-175.e9
artikel
34 Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species Stein-O’Brien, Genevieve L.

2 p. 203
artikel
35 Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States Kim, Jong Wook
2017
2 p. 105-118.e9
1.17999999896E11 p.
artikel
36 Deep Proteome Analysis Identifies Age-Related Processes in C. elegans Narayan, Vikram
2016
2 p. 144-159
16 p.
artikel
37 Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate Corwin, Thomas
2017
2 p. 128-139.e4
1.389873E6 p.
artikel
38 Design of Adjacent Transcriptional Regions to Tune Gene Expression and Facilitate Circuit Construction Wu, Fuqing

2 p. 206-215.e6
artikel
39 Determination of the Gene Regulatory Network of a Genome-Reduced Bacterium Highlights Alternative Regulation Independent of Transcription Factors Yus, Eva
2019
2 p. 143-158.e13
artikel
40 Differential Allele-Specific Expression Uncovers Breast Cancer Genes Dysregulated by Cis Noncoding Mutations Przytycki, Pawel F.

2 p. 193-203.e4
artikel
41 Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling Rukhlenko, Oleksii S.

2 p. 161-179.e14
artikel
42 Editorial Transparency 2017
2 p. 139
artikel
43 Entropy-Scaling Search of Massive Biological Data Yu, Y. William
2015
2 p. 130-140
11 p.
artikel
44 Evaluation of Chen et al.: Overexpression of Protein Complexes and Aneuploidy Amon, Angelika
2019
2 p. 107-108
artikel
45 Evaluation of Kuroda et al.: Insight into Yeast Isobutanol Tolerance with Advances Still Needed Hittinger, Chris Todd

2 p. 124
artikel
46 Evaluation of Ravindran et al.: Real-time detection of signaling pulses in vivo: making cells monitor themselves Garcia-Ojalvo, Jordi

2 p. 105-106
artikel
47 Even Noisy Responses Can Be Perfect If Integrated Properly Doyle, John C.
2016
2 p. 73-75
3 p.
artikel
48 Evolutionary Inference across Eukaryotes Identifies Specific Pressures Favoring Mitochondrial Gene Retention Johnston, Iain G.
2016
2 p. 101-111
11 p.
artikel
49 Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results Riba, Andrea
2017
2 p. 182-193.e4
artikel
50 Fast, Quantitative and Variant Enabled Mapping of Peptides to Genomes Schlaffner, Christoph N.
2017
2 p. 152-156.e4
1.559849E6 p.
artikel
51 Finding the Optimal Tradeoffs Mathew, Shibin
2017
2 p. 149-151
artikel
52 FLASHDeconv: Ultrafast, High-Quality Feature Deconvolution for Top-Down Proteomics Jeong, Kyowon

2 p. 213-218.e6
artikel
53 From Yeast to Patients: The Audacity and Vision of Susan Lindquist Khurana, Vikram
2017
2 p. 147-148
artikel
54 Fundamental Limits of Search Kannan, Sreeram
2015
2 p. 102-103
2 p.
artikel
55 GCN2 adapts protein synthesis to scavenging-dependent growth Nofal, Michel

2 p. 158-172.e9
artikel
56 GeneGini: Assessment via the Gini Coefficient of Reference “Housekeeping” Genes and Diverse Human Transporter Expression Profiles O'Hagan, Steve

2 p. 230-244.e1
artikel
57 Generalizable and Scalable Visualization of Single-Cell Data Using Neural Networks Cho, Hyunghoon

2 p. 185-191.e4
artikel
58 Gene Regulatory Strategies that Decode the Duration of NFκB Dynamics Contribute to LPS- versus TNF-Specific Gene Expression Sen, Supriya

2 p. 169-182.e5
artikel
59 Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways Khurana, Vikram
2017
2 p. 157-170.e14
artikel
60 Genome-Scale Transcriptional Regulatory Network Models of Psychiatric and Neurodegenerative Disorders Pearl, Jocelynn R.
2019
2 p. 122-135.e7
artikel
61 Genomic Recoding Broadly Obstructs the Propagation of Horizontally Transferred Genetic Elements Ma, Natalie Jing
2016
2 p. 199-207
9 p.
artikel
62 Growth-Optimized Aminoacyl-tRNA Synthetase Levels Prevent Maximal tRNA Charging Parker, Darren J.

2 p. 121-130.e6
artikel
63 High-Throughput Affinity Measurements of Transcription Factor and DNA Mutations Reveal Affinity and Specificity Determinants Aditham, Arjun K.

2 p. 112-127.e11
artikel
64 How Can Systems Biology Test Principles and Tools Using Immune Cells as a Model?
2 p. 146-148
artikel
65 How Does Large-Scale Genomic Analysis Shape Our Understanding of COVID Variants in Real Time? van Dorp, Lucy

2 p. 109-111
artikel
66 “How Do You Know?” The Answer Lies in Methods Justman, Quincey

2 p. 121
artikel
67 How to Understand Systems Mak, H. Craig
2015
2 p. 99-
1 p.
artikel
68 How Will Kinetics and Thermodynamics Inform Our Future Efforts to Understand and Build Biological Systems? 2017
2 p. 144-146
artikel
69 Hunting for Cis-Regulatory Elements in Proteins Gibson, Toby J.
2016
2 p. 68-70
3 p.
artikel
70 Inferring Regulatory Programs Governing Region Specificity of Neuroepithelial Stem Cells during Early Hindbrain and Spinal Cord Development Chasman, Deborah
2019
2 p. 167-186.e12
artikel
71 Insights into the Mechanisms of Basal Coordination of Transcription Using a Genome-Reduced Bacterium Junier, Ivan

2 p. 227-229
artikel
72 In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons Chung, Chee Yeun
2017
2 p. 242-250.e4
artikel
73 Integrative Personal Omics Profiles during Periods of Weight Gain and Loss Piening, Brian D.

2 p. 157-170.e8
artikel
74 In the Future, Data and Code Should Be FAIR Justman, Quincey
2019
2 p. 95
artikel
75 In This Issue 2016
2 p. ix-
1 p.
artikel
76 In This Issue 2015
2 p. ix-
1 p.
artikel
77 Joint Analysis of Long and Short Reads Enables Accurate Estimates of Microbiome Complexity Bankevich, Anton

2 p. 192-200.e3
artikel
78 Juicebox.js Provides a Cloud-Based Visualization System for Hi-C Data Robinson, James T.

2 p. 256-258.e1
artikel
79 Keeping the Proportions of Protein Complex Components in Check Taggart, James Christopher

2 p. 125-132
artikel
80 Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan Baumgart, Mario
2016
2 p. 122-132
11 p.
artikel
81 Mantis: A Fast, Small, and Exact Large-Scale Sequence-Search Index Pandey, Prashant

2 p. 201-207.e4
artikel
82 Mapping combinatorial expression perturbations to growth in Escherichia coli McCain, J. Scott P.

2 p. 106-108
artikel
83 Maximum Entropy Framework for Predictive Inference of Cell Population Heterogeneity and Responses in Signaling Networks Dixit, Purushottam D.

2 p. 204-212.e8
artikel
84 Merged Map of the Yeast Proteome Schmidt, Alexander

2 p. 150-152
artikel
85 Metabolic models of human gut microbiota: Advances and challenges Rios Garza, Daniel

2 p. 109-121
artikel
86 Modeling the Future Mak, H. Craig
2016
2 p. 109-
1 p.
artikel
87 Molecular and Functional Networks Linked to Sarcopenia Prevention by Caloric Restriction in Rhesus Monkeys Rhoads, Timothy W.

2 p. 156-168.e5
artikel
88 Molecular Time Sharing through Dynamic Pulsing in Single Cells Park, Jin

2 p. 216-229.e15
artikel
89 Navigating the Cancer Transcriptome by Decoding Divergent Oncogenic States Amin, Samirkumar B.
2017
2 p. 90-92
3 p.
artikel
90 Network Architecture Predisposes an Enzyme to Either Pharmacologic or Genetic Targeting Jensen, Karin J.
2016
2 p. 112-121
10 p.
artikel
91 Optimal Regulatory Circuit Topologies for Fold-Change Detection Adler, Miri
2017
2 p. 171-181.e8
artikel
92 Overdosage of Balanced Protein Complexes Reduces Proliferation Rate in Aneuploid Cells Chen, Ying
2019
2 p. 129-142.e5
artikel
93 Parallelization and High-Performance Computing Enables Automated Statistical Inference of Multi-scale Models Jagiella, Nick
2017
2 p. 194-206.e9
artikel
94 Perfect and Near-Perfect Adaptation in Cell Signaling Ferrell Jr., James E.
2016
2 p. 62-67
6 p.
artikel
95 Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma Golkowski, Martin

2 p. 196-207.e7
artikel
96 Phylogenetic Profiling for Probing the Modular Architecture of the Human Genome Dey, Gautam
2015
2 p. 106-115
10 p.
artikel
97 Pitfalls of genotyping microbial communities with rapidly growing genome collections Zhao, Chunyu

2 p. 160-176.e3
artikel
98 Positive Gradients Mak, Craig
2015
2 p. 174-
1 p.
artikel
99 Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids D'Ippolito, Anthony M.

2 p. 146-160.e7
artikel
100 Principles of Systems Biology, No. 2 2016
2 p. 60-61
2 p.
artikel
101 Principles of Systems Biology, No. 20 2017
2 p. 88-89
2 p.
artikel
102 Principles of Systems Biology, No. 8 2016
2 p. 110-113
4 p.
artikel
103 Principles of Systems Biology, No. 14 2017
2 p. 140-143
artikel
104 Principles of Systems Biology, No. 26
2 p. 143-145
artikel
105 Principles of Systems Biology, No. 31 Cho, Hyunghoon

2 p. 133-135
artikel
106 Privacy-preserving genotype imputation with fully homomorphic encryption Gürsoy, Gamze

2 p. 173-182.e3
artikel
107 Protein Networks in Alzheimer’s Disease Carlsen, Eva Meier
2017
2 p. 153-155
artikel
108 Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals Hark, Timothy J.

2 p. 141-158.e9
artikel
109 Quantification of Uncertainty in Peptide-MHC Binding Prediction Improves High-Affinity Peptide Selection for Therapeutic Design Zeng, Haoyang
2019
2 p. 159-166.e3
artikel
110 Quantifying Drug Combination Synergy along Potency and Efficacy Axes Meyer, Christian T.
2019
2 p. 97-108.e16
artikel
111 Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome Wang, Tina

2 p. 176-185.e6
artikel
112 Rare Cell Detection by Single-Cell RNA Sequencing as Guided by Single-Molecule RNA FISH Torre, Eduardo

2 p. 171-179.e5
artikel
113 RBM-MHC: A Semi-Supervised Machine-Learning Method for Sample-Specific Prediction of Antigen Presentation by HLA-I Alleles Bravi, Barbara

2 p. 195-202.e9
artikel
114 Remote-Controlled Mice Anikeeva, Polina
2015
2 p. 104-105
2 p.
artikel
115 Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells Jain, Naveen

2 p. 109-133.e10
artikel
116 ROS and Oxidative Stress Are Elevated in Mitosis during Asynchronous Cell Cycle Progression and Are Exacerbated by Mitotic Arrest Patterson, Jesse C.
2019
2 p. 163-167.e2
artikel
117 Science that Inspires
2 p. 122-123
artikel
118 Scikit-ribo Enables Accurate Estimation and Robust Modeling of Translation Dynamics at Codon Resolution Fang, Han

2 p. 180-191.e4
artikel
119 Semblance of Heterogeneity in Collective Cell Migration Schumacher, Linus J.
2017
2 p. 119-127.e1
1152 p.
artikel
120 Sensing the Right Time to Be Productive Ceroni, Francesca
2016
2 p. 116-117
2 p.
artikel
121 Signal Percolation within a Bacterial Community Larkin, Joseph W.

2 p. 137-145.e3
artikel
122 Simple visualization of submicroscopic protein clusters with a phase-separation-based fluorescent reporter Mumford, Thomas R.

2 p. 166-179.e7
artikel
123 Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity Blecher-Gonen, Ronnie
2019
2 p. 109-121.e6
artikel
124 Single-cell colocalization analysis using a deep generative model Kojima, Yasuhiro

2 p. 180-192.e7
artikel
125 SingleCellNet: A Computational Tool to Classify Single Cell RNA-Seq Data Across Platforms and Across Species Tan, Yuqi
2019
2 p. 207-213.e2
artikel
126 Spatial self-organization of metabolism in microbial systems: A matter of enzymes and chemicals Dal Co, Alma

2 p. 98-108
artikel
127 Statistical Binning for Barcoded Reads Improves Downstream Analyses Shajii, Ariya

2 p. 219-226.e5
artikel
128 Stochastic Self-Assembly of ParB Proteins Builds the Bacterial DNA Segregation Apparatus Sanchez, Aurore
2015
2 p. 163-173
11 p.
artikel
129 Switch-like Transitions Insulate Network Motifs to Modularize Biological Networks Atay, Oguzhan
2016
2 p. 121-132
12 p.
artikel
130 SYGNALing a Red Light for Glioblastoma Brooks, Aaron N.
2016
2 p. 118-120
3 p.
artikel
131 Synthetic Gene Circuits Learn to Classify Didovyk, Andriy
2017
2 p. 151-153
artikel
132 Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells Ding, Li
2015
2 p. 141-151
11 p.
artikel
133 Systems Biology of Cancer Metastasis Suhail, Yasir
2019
2 p. 109-127
artikel
134 Systems-Level Properties of EGFR-RAS-ERK Signaling Amplify Local Signals to Generate Dynamic Gene Expression Heterogeneity Davies, Alexander E.

2 p. 161-175.e5
artikel
135 Systems-wide Identification of cis-Regulatory Elements in Proteins Yeon, Ju Hun
2016
2 p. 89-100
12 p.
artikel
136 The Cell Cycle Browser: An Interactive Tool for Visualizing, Simulating, and Perturbing Cell-Cycle Progression Borland, David

2 p. 180-184.e4
artikel
137 The community-function landscape of microbial consortia Sanchez, Alvaro

2 p. 122-134
artikel
138 The GenePattern Notebook Environment Reich, Michael
2017
2 p. 149-151.e1
1362 p.
artikel
139 The Key Parameters that Govern Translation Efficiency Erdmann-Pham, Dan D.

2 p. 183-192.e6
artikel
140 The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent manner Hamelin, David J.

2 p. 143-157.e3
artikel
141 Tissue Architectural Cues Drive Organ Targeting of Tumor Cells in Zebrafish Paul, Colin D.
2019
2 p. 187-206.e16
artikel
142 Tissue Schematics: A framework to decipher tissue architecture and assembly Setty, Manu

2 p. 107-108
artikel
143 Tissue schematics map the specialization of immune tissue motifs and their appropriation by tumors Bhate, Salil S.

2 p. 109-130.e6
artikel
144 Transcriptional Intricacies of Stem Cells Hutchins, Andrew P.
2015
2 p. 100-101
2 p.
artikel
145 Transcription Factor Activity Mapping of a Tissue-Specific In Vivo Gene Regulatory Network MacNeil, Lesley T.
2015
2 p. 152-162
11 p.
artikel
146 Transcription Factor Competition Allows Embryonic Stem Cells to Distinguish Authentic Signals from Noise Sokolik, Cameron
2015
2 p. 117-129
13 p.
artikel
147 Translation Initiation Site Profiling Reveals Widespread Synthesis of Non-AUG-Initiated Protein Isoforms in Yeast Eisenberg, Amy R.

2 p. 145-160.e5
artikel
148 Translation of Genotype to Phenotype by a Hierarchy of Cell Subsystems Yu, Michael Ku
2016
2 p. 77-88
12 p.
artikel
149 Unification of Protein Abundance Datasets Yields a Quantitative Saccharomyces cerevisiae Proteome Ho, Brandon

2 p. 192-205.e3
artikel
150 Universal Alternative Splicing of Noncoding Exons Deveson, Ira W.

2 p. 245-255.e5
artikel
151 What do you most want to understand about how collective features emerge in microbial communities? Segrè, Daniel

2 p. 91-97
artikel
152 What is the key challenge in engineering microbiomes? Venturelli, Ophelia S.

2 p. 85-90
artikel
153 When Seeing Isn't Believing: How Math Can Guide Our Interpretation of Measurements and Experiments Macklin, Paul
2017
2 p. 92-94
3 p.
artikel
154 Why Do Fast-Growing Bacteria Enter Overflow Metabolism? Testing the Membrane Real Estate Hypothesis Szenk, Mariola
2017
2 p. 95-104
10 p.
artikel
155 Why Have Organelles Retained Genomes? Allen, John F.
2016
2 p. 70-72
3 p.
artikel
                             155 gevonden resultaten
 
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