Digitale Bibliotheek
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                             95 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A combination of LightOn gene expression system and tumor microenvironment-responsive nanoparticle delivery system for targeted breast cancer therapy Hou, Xinyu

9 p. 1741-1753
artikel
2 Amelioration of ethanol-induced oxidative stress and alcoholic liver disease by in vivo RNAi targeting Cyp2e1 Wang, Yalan

9 p. 3906-3918
artikel
3 An integrative approach of digital image analysis and transcriptome profiling to explore potential predictive biomarkers for TGFβ blockade therapy Pomponio, Robert

9 p. 3594-3601
artikel
4 An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation Harms, Mirja

9 p. 2694-2708
artikel
5 A novel ω-conotoxin Bu8 inhibiting N-type voltage-gated calcium channels displays potent analgesic activity Chen, Jinqin

9 p. 2685-2693
artikel
6 Antitumor synergism between PAK4 silencing and immunogenic phototherapy of engineered extracellular vesicles Lu, Mei

9 p. 3945-3955
artikel
7 Apoptosis-inducing activity of synthetic hydrocarbon-stapled peptides in H358 cancer cells expressing KRASG12C Li, Cuicui

9 p. 2670-2684
artikel
8 Aureane-type sesquiterpene tetraketides as a novel class of immunomodulators with interleukin-17A inhibitory activity Tang, Xin

9 p. 3930-3944
artikel
9 Author correction to ‘Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties: Preparation, characterization and application in vaginal drug delivery system’ [Acta Pharm Sin B 7 (2017) 593–602] Ci, Li-qian

9 p. 3961-3962
artikel
10 Author correction to ‘TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner’ [Acta Pharmaceutica Sinica B 11 (2021) 3994–4007] Zheng, Huaqing

9 p. 3956-3960
artikel
11 Bispecific antibodies in cancer therapy: Target selection and regulatory requirements Sun, Yanze

9 p. 3583-3597
artikel
12 Bladder microenvironment actuated proteomotors with ammonia amplification for enhanced cancer treatment Tian, Hao

9 p. 3862-3875
artikel
13 Brain endothelial cell-derived extracellular vesicles with a mitochondria-targeting photosensitizer effectively treat glioblastoma by hijacking the blood‒brain barrier Nguyen Cao, Thuy Giang

9 p. 3834-3848
artikel
14 Characterization of the depsidone gene cluster reveals etherification, decarboxylation and multiple halogenations as tailoring steps in depsidone assembly Yang, Jiafan

9 p. 3919-3929
artikel
15 Clinical efficacies, underlying mechanisms and molecular targets of Chinese medicines for diabetic nephropathy treatment and management Tang, Guoyi

9 p. 2749-2767
artikel
16 Combination therapy using microwave ablation and d-mannose-chelated iron oxide nanoparticles inhibits hepatocellular carcinoma progression Cui, Rui

9 p. 3475-3485
artikel
17 Combination therapy with miR34a and doxorubicin synergistically inhibits Dox-resistant breast cancer progression via down-regulation of Snail through suppressing Notch/NF-κB and RAS/RAF/MEK/ERK signaling pathway Yang, Xiaoxia

9 p. 2819-2834
artikel
18 Combining immune checkpoint blockade with ATP-based immunogenic cell death amplifier for cancer chemo-immunotherapy Zhang, Jiulong

9 p. 3694-3709
artikel
19 Computed tomography and photoacoustic imaging guided photodynamic therapy against breast cancer based on mesoporous platinum with insitu oxygen generation ability Zhang, Lingyan

9 p. 1719-1729
artikel
20 Cooperative coordination-mediated multi-component self-assembly of “all-in-one” nanospike theranostic nano-platform for MRI-guided synergistic therapy against breast cancer Chen, Xiaojie

9 p. 3710-3725
artikel
21 Cover Story
9 p. ix
artikel
22 Cover Story
9 p. x
artikel
23 Cover Story
9 p. viii
artikel
24 Cover Story
9 p. xi
artikel
25 Critical involvement of lysyl oxidase in seizure-induced neuronal damage through ERK-Alox5-dependent ferroptosis and its therapeutic implications Mao, Xiaoyuan

9 p. 3513-3528
artikel
26 Cyclin-dependent kinases-based synthetic lethality: Evidence, concept, and strategy Li, Kailin

9 p. 2738-2748
artikel
27 Deficiency of anti-inflammatory cytokine IL-4 leads to neural hyperexcitability and aggravates cerebral ischemia–reperfusion injury Chen, Xiaoling

9 p. 1634-1645
artikel
28 Design of ultrahigh-affinity and dual-specificity peptide antagonists of MDM2 and MDMX for P53 activation and tumor suppression Li, Xiang

9 p. 2655-2669
artikel
29 Design, synthesis, and biological evaluation of multiple targeting antimalarials Yang, Yiqing

9 p. 2900-2913
artikel
30 Discovery of an orally effective double-stapled peptide for reducing ovariectomy-induced bone loss in mice Cong, Wei

9 p. 3770-3781
artikel
31 Discovery of a potent and dual-selective bisubstrate inhibitor for protein arginine methyltransferase 4/5 Al-Hamashi, Ayad A.

9 p. 2709-2718
artikel
32 Discovery of novel aporphine alkaloid derivative as potent TLR2 antagonist reversing macrophage polarization and neutrophil infiltration against acute inflammation Yang, Junjie

9 p. 3782-3801
artikel
33 Disease-specific protein corona formed in pathological intestine enhances the oral absorption of nanoparticles Wu, Jiawei

9 p. 3876-3891
artikel
34 Dual-targeting prodrug nanotheranostics for NIR-Ⅱ fluorescence imaging-guided photo-immunotherapy of glioblastoma Li, Fenglin

9 p. 3486-3497
artikel
35 Editorial of Special Column “Novel Peptides and Peptidomimetics in Drug Discovery” Cai, Jianfeng

9 p. 2606-2608
artikel
36 Editorial of Special Column on A New Era of Nanobiomaterial-based Drug Delivery Yu, Haijun

9 p. 3453-3455
artikel
37 Editor Profiles: Guest Editors of Special Column “Novel Peptides and Peptidomimetics in Drug Discovery”
9 p. 2605
artikel
38 Exploration of 5-cyano-6-phenylpyrimidin derivatives containing an 1,2,3-triazole moiety as potent FAD-based LSD1 inhibitors Ma, Liying

9 p. 1658-1668
artikel
39 Facile synthesis of insulin fusion derivatives through sortase A ligation Disotuar, Maria M.

9 p. 2719-2725
artikel
40 First small-molecule PROTACs for G protein-coupled receptors: inducing α 1A-adrenergic receptor degradation Li, Zhenzhen

9 p. 1669-1679
artikel
41 FOXO3 mutation predicting gefitinib-induced hepatotoxicity in NSCLC patients through regulation of autophagy Guan, Shaoxing

9 p. 3639-3649
artikel
42 Functional annotation map of natural compounds in traditional Chinese medicines library: TCMs with myocardial protection as a case Xing, Xudong

9 p. 3802-3816
artikel
43 Functional nano-vector boost anti-atherosclerosis efficacy of berberine in Apoe (−/−) mice Ma, Xiaolei

9 p. 1769-1783
artikel
44 Gasdermin D in pyroptosis Burdette, Brandon E.

9 p. 2768-2782
artikel
45 Gastrin attenuates sepsis-induced myocardial dysfunction by down-regulation of TLR4 expression in macrophages Fang, Dandong

9 p. 3756-3769
artikel
46 Gestational dexamethasone exposure impacts hippocampal excitatory synaptic transmission and learning and memory function with transgenerational effects Luo, Mingcui

9 p. 3708-3727
artikel
47 Glycoside scutellarin enhanced CD-MOF anchoring for laryngeal delivery Zhao, Kena

9 p. 1709-1718
artikel
48 Hepatic retinaldehyde deficiency is involved in diabetes deterioration by enhancing PCK1- and G6PC-mediated gluconeogenesis Yang, Hanyu

9 p. 3728-3743
artikel
49 Icariside Ⅱ, a main compound in Epimedii Folium, induces idiosyncratic hepatotoxicity by enhancing NLRP3 inflammasome activation Wang, Zhilei

9 p. 1619-1633
artikel
50 Identification of bioactive anti-angiogenic components targeting tumor endothelial cells in Shenmai injection using multidimensional pharmacokinetics Zhong, Chongjin

9 p. 1694-1708
artikel
51 Inhibition of ASCT2 induces hepatic stellate cell senescence with modified proinflammatory secretome through an IL-1α/NF-κB feedback pathway to inhibit liver fibrosis Wang, Feixia

9 p. 3618-3638
artikel
52 Inhibition of post-trabeculectomy fibrosis via topically instilled antisense oligonucleotide complexes co-loaded with fluorouracil Jiang, Kuan

9 p. 1754-1768
artikel
53 I n situ synthesis and unidirectional insertion of membrane proteins in liposome-immobilized silica stationary phase for rapid preparation of microaffinity chromatography Gu, Yanqiu

9 p. 3682-3693
artikel
54 Integrins as attractive targets for cancer therapeutics Li, Meng

9 p. 2726-2737
artikel
55 Lenvatinib- and vadimezan-loaded synthetic high-density lipoprotein for combinational immunochemotherapy of metastatic triple-negative breast cancer Zheng, Chao

9 p. 3726-3738
artikel
56 LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation Sun, Jian

9 p. 3602-3617
artikel
57 Lonicerin targets EZH2 to alleviate ulcerative colitis by autophagy-mediated NLRP3 inflammasome inactivation Lv, Qi

9 p. 2880-2899
artikel
58 LPS adsorption and inflammation alleviation by polymyxin B-modified liposomes for atherosclerosis treatment Liu, Huiwen

9 p. 3817-3833
artikel
59 Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era Lin, Liming

9 p. 2609-2644
artikel
60 Molecular glues modulate protein functions by inducing protein aggregation: A promising therapeutic strategy of small molecules for disease treatment Wu, Hongyu

9 p. 3548-3566
artikel
61 Mucosal vaccine delivery: A focus on the breakthrough of specific barriers Huang, Mengwen

9 p. 3456-3474
artikel
62 Multi-functional vesicles improve Helicobacter pylori eradication by a comprehensive strategy based on complex pathological microenvironment Chen, Xiaonan

9 p. 3498-3512
artikel
63 Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine Wang, Xuan

9 p. 3567-3593
artikel
64 Nonclinical safety, tolerance and pharmacodynamics evaluation for meplazumab treating chloroquine-resistant Plasmodium falciparum Zhang, Kun

9 p. 1680-1693
artikel
65 Novel compound FLZ alleviates rotenone-induced PD mouse model by suppressing TLR4/MyD88/NF-κB pathway through microbiota–gut–brain axis Zhao, Zhe

9 p. 2859-2879
artikel
66 Orchestrating antigen delivery and presentation efficiency in lymph node by nanoparticle shape for immune response Zhao, Hongjuan

9 p. 3892-3905
artikel
67 Peptidomimetic-based antibody surrogate for HER2 Zheng, Mengmeng

9 p. 2645-2654
artikel
68 Polymyxin resistance caused by large-scale genomic inversion due to IS26 intramolecular translocation in Klebsiella pneumoniae Li, Haibin

9 p. 3678-3693
artikel
69 Potential herb–drug interactions between anti-COVID-19 drugs and traditional Chinese medicine Ye, Ling

9 p. 3598-3637
artikel
70 Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy Hu, Chen

9 p. 3694-3707
artikel
71 Rapid screening of SARS-CoV-2 inhibitors via ratiometric fluorescence of RBD–ACE2 complexes in living cells by competitive binding Miao, Lu

9 p. 3739-3742
artikel
72 Recent advances of antibody drug conjugates for clinical applications Zhao, Pengxuan

9 p. 1589-1600
artikel
73 Receptor-mediated targeted drug delivery systems for treatment of inflammatory bowel disease: Opportunities and emerging strategies Liu, Peng

9 p. 2798-2818
artikel
74 Reconstitution of biosynthetic pathway for mushroom-derived cyathane diterpenes in yeast and generation of new “non-natural” analogues Ma, Ke

9 p. 2945-2956
artikel
75 Regulating the microenvironment with nanomaterials: Potential strategies to ameliorate COVID-19 Liu, Zhicheng

9 p. 3638-3658
artikel
76 Remote loading paclitaxel–doxorubicin prodrug into liposomes for cancer combination therapy Yu, Jiang

9 p. 1730-1740
artikel
77 Repurposing carrimycin as an antiviral agent against human coronaviruses, including the currently pandemic SARS-CoV-2 Yan, Haiyan

9 p. 2850-2858
artikel
78 Research advances in peptide‒drug conjugates Gong, Liming

9 p. 3659-3677
artikel
79 Self-assembled natural phytochemicals for synergistically antibacterial application from the enlightenment of traditional Chinese medicine combination Tian, Xuehao

9 p. 1784-1795
artikel
80 Self-assembly of CXCR4 antagonist peptide–docetaxel conjugates for breast tumor multi-organ metastasis inhibition Li, Chen

9 p. 3849-3861
artikel
81 Self-propelled nanomotor reconstructs tumor microenvironment through synergistic hypoxia alleviation and glycolysis inhibition for promoted anti-metastasis Yu, Wenqi

9 p. 2924-2936
artikel
82 Simultaneous improvement to solubility and bioavailability of active natural compound isosteviol using cyclodextrin metal-organic frameworks Chen, Xiaojin

9 p. 2914-2923
artikel
83 Small molecule SMU-CX24 targeting toll-like receptor 3 counteracts inflammation: A novel approach to atherosclerosis therapy Cen, Xiaohong

9 p. 3667-3681
artikel
84 Table of Contents
9 p. iii-ix
artikel
85 Table of Contents
9 p. iii-x
artikel
86 Table of Contents
9 p. iii-vii
artikel
87 Table of Contents
9 p. iii-xi
artikel
88 Targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease Tong, Jie

9 p. 3650-3666
artikel
89 Targeting necroptosis in anticancer therapy: mechanisms and modulators Wu, Ying

9 p. 1601-1618
artikel
90 The biology, function, and applications of exosomes in cancer Liu, Jinyi

9 p. 2783-2797
artikel
91 Therapeutic potential of traditional Chinese medicine for the treatment of NAFLD: A promising drug Potentilla discolor Bunge Ji, Longshan

9 p. 3529-3547
artikel
92 Transdermal delivery of Chinese herbal medicine extract using dissolvable microneedles for hypertrophic scar treatment Ning, Xiaoyu

9 p. 2937-2944
artikel
93 Translocation of IGF-1R in endoplasmic reticulum enhances SERCA2 activity to trigger Ca2+ ER perturbation in hepatocellular carcinoma Li, Yanan

9 p. 3744-3755
artikel
94 Transporters (OATs and OATPs) contribute to illustrate the mechanism of medicinal compatibility of ingredients with different properties in yuanhuzhitong prescription Wang, Ze

9 p. 1646-1657
artikel
95 Tryptophan 2,3-dioxygenase 2 controls M2 macrophages polarization to promote esophageal squamous cell carcinoma progression via AKT/GSK3β/IL-8 signaling pathway Zhao, Yumiao

9 p. 2835-2849
artikel
                             95 gevonden resultaten
 
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