nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
Accelerating lead development by microwave-enhanced medicinal chemistry
|
Shipe, William D. |
|
2005 |
|
2 |
p. 155-161 7 p. |
artikel |
2 |
A critical path approach to advance nanoengineered medical products
|
Sanhai, Wendy R. |
|
2007 |
|
2 |
p. 35-41 7 p. |
artikel |
3 |
Advanced behavioural screening: automated home cage ethology
|
Spruijt, Berry M. |
|
2006 |
|
2 |
p. 231-237 7 p. |
artikel |
4 |
Advancing women's health via FDA Critical Path Initiative
|
Parekh, A. |
|
2007 |
|
2 |
p. 69-73 5 p. |
artikel |
5 |
Affinity separation: divide and conquer the proteome
|
Fang, Xiangming |
|
2004 |
|
2 |
p. 141-148 8 p. |
artikel |
6 |
An overview of e-Clinical trials
|
Bunn, Graham |
|
2006 |
|
2 |
p. 163-166 4 p. |
artikel |
7 |
Assessment of visual performance in the evaluation of new medical products
|
Drum, B. |
|
2007 |
|
2 |
p. 55-61 7 p. |
artikel |
8 |
Blood safety: Opportunities and challenges addressed through Critical Path research at FDA
|
Atreya, Chintamani D. |
|
2007 |
|
2 |
p. 51-54 4 p. |
artikel |
9 |
Capillary electrophoresis technologies for screening in drug discovery
|
Wan, Hong |
|
2005 |
|
2 |
p. 171-178 8 p. |
artikel |
10 |
Complementary molecular imaging technologies: High resolution SPECT, PET and MRI
|
Meikle, Steven R. |
|
2006 |
|
2 |
p. 187-194 8 p. |
artikel |
11 |
Content
|
|
|
2005 |
|
2 |
p. i- 1 p. |
artikel |
12 |
Contents
|
|
|
2010 |
|
2 |
p. i- 1 p. |
artikel |
13 |
Contents
|
|
|
2004 |
|
2 |
p. i- 1 p. |
artikel |
14 |
Contents
|
|
|
2007 |
|
2 |
p. i- 1 p. |
artikel |
15 |
Current methods for high-throughput detection of novel DNA polymorphisms
|
Peters, Thomas |
|
2006 |
|
2 |
p. 123-129 7 p. |
artikel |
16 |
Development and validation of novel imaging technologies to assist translational studies in atherosclerosis
|
Miserus, Robbert-Jan J.H.M. |
|
2006 |
|
2 |
p. 195-204 10 p. |
artikel |
17 |
Developments in modulating protein function for effective target validation
|
Ilag, Leodevico L. |
|
2004 |
|
2 |
p. 113-117 5 p. |
artikel |
18 |
Drug eluting stents and the critical path initiative: Evolving paradigms for safety evaluation
|
Sanhai, Wendy R. |
|
2007 |
|
2 |
p. 43-46 4 p. |
artikel |
19 |
e-Clinical integration strategies
|
Howells, Keith |
|
2006 |
|
2 |
p. 167-171 5 p. |
artikel |
20 |
Editorial
|
|
|
2006 |
|
2 |
p. 111-114 4 p. |
artikel |
21 |
Editorial
|
|
|
2005 |
|
2 |
p. iii-iv nvt p. |
artikel |
22 |
Enhanced brain drug delivery: safely crossing the blood–brain barrier
|
Gaillard, Pieter J. |
|
2012 |
|
2 |
p. e155-e160 nvt p. |
artikel |
23 |
Enhanced permeability and retention effect for selective targeting of anticancer nanomedicine: are we there yet?
|
Greish, Khaled |
|
2012 |
|
2 |
p. e161-e166 nvt p. |
artikel |
24 |
Fall and rise of behavioural pharmacology
|
de Graaf, Joop S. |
|
2006 |
|
2 |
p. 181-185 5 p. |
artikel |
25 |
FDA's Critical Path Initiative
|
Woodcock, Janet |
|
2007 |
|
2 |
p. 33- 1 p. |
artikel |
26 |
Formulation technologies to overcome poor drug-like properties
|
Alfredson, Tom |
|
2012 |
|
2 |
p. e71-e72 nvt p. |
artikel |
27 |
Formulation technologies to overcome unfavorable properties of peptides and proteins for pulmonary delivery
|
Wan, Feng |
|
2012 |
|
2 |
p. e141-e146 nvt p. |
artikel |
28 |
From differential gene expression to differential gene function and back
|
Chatterjee-Kishore, Moitreyee |
|
2004 |
|
2 |
p. 149-156 8 p. |
artikel |
29 |
From genes to drugs: target validation in Caenorhabditis elegans
|
Sluder, Ann E. |
|
2004 |
|
2 |
p. 171-177 7 p. |
artikel |
30 |
Functional genomics and target gene validation in experimental and human disease
|
Schulte, Johannes H. |
|
2004 |
|
2 |
p. 105-111 7 p. |
artikel |
31 |
Gene mapping strategies for complex disease and drug response
|
Jawaid, Ansar |
|
2006 |
|
2 |
p. 131-136 6 p. |
artikel |
32 |
Genome scale cytometry: High content analysis for high throughput RNAi phenotype profiling
|
Evans, David M. |
|
2005 |
|
2 |
p. 141-147 7 p. |
artikel |
33 |
Genotyping technologies for all
|
Ragoussis, Jiannis |
|
2006 |
|
2 |
p. 115-122 8 p. |
artikel |
34 |
Global gene expression analysis in the zebrafish: the challenge and the promise
|
Pichler, Franz B. |
|
2004 |
|
2 |
p. 79-84 6 p. |
artikel |
35 |
G-protein-coupled receptor screening technologies
|
Greasley, Peter J. |
|
2005 |
|
2 |
p. 163-170 8 p. |
artikel |
36 |
Insight of current technologies for oral delivery of proteins and peptides
|
Chin, Jungwook |
|
2012 |
|
2 |
p. e105-e112 nvt p. |
artikel |
37 |
Integrative bioinformatics: making sense of the networks
|
Wodak, Shoshana J. |
|
2004 |
|
2 |
p. 179-187 9 p. |
artikel |
38 |
Ion channel screening technologies today
|
Terstappen, Georg C. |
|
2005 |
|
2 |
p. 133-140 8 p. |
artikel |
39 |
Lipid-based formulations for oral delivery of lipophilic drugs
|
Kuentz, Martin |
|
2012 |
|
2 |
p. e97-e104 nvt p. |
artikel |
40 |
Lost in translation? Role of metabolomics in solving translational problems in drug discovery and development
|
van der Greef, Jan |
|
2006 |
|
2 |
p. 205-211 7 p. |
artikel |
41 |
Medium-sized molecules – Fertile or futile ground for drug discovery?
|
Zhang, Ming-Qiang |
|
2010 |
|
2 |
p. e95-e96 nvt p. |
artikel |
42 |
Methods for the synthesis of macrocycle libraries for drug discovery
|
Terrett, Nicholas K. |
|
2010 |
|
2 |
p. e97-e104 nvt p. |
artikel |
43 |
Microarrays meet the Voltaire challenge: Drug discovery on a chip?
|
Jackson, David B. |
|
2006 |
|
2 |
p. 153-161 9 p. |
artikel |
44 |
Multiplexed high content screening assays create a systems cell biology approach to drug discovery
|
Taylor, D. Lansing |
|
2005 |
|
2 |
p. 149-154 6 p. |
artikel |
45 |
Mycobacterial genetics in target validation
|
Warner, Digby F. |
|
2004 |
|
2 |
p. 93-98 6 p. |
artikel |
46 |
Nanobodies – from llamas to therapeutic proteins
|
Kolkman, Joost A. |
|
2010 |
|
2 |
p. e139-e146 nvt p. |
artikel |
47 |
Optimizing the physical form – opportunities and limitations
|
Byrn, Stephen R. |
|
2012 |
|
2 |
p. e73-e78 nvt p. |
artikel |
48 |
Overcoming poor oral bioavailability using nanoparticle formulations – opportunities and limitations
|
Desai, Preshita P. |
|
2012 |
|
2 |
p. e87-e95 nvt p. |
artikel |
49 |
Overcoming poor permeability – the role of prodrugs for oral drug delivery
|
Maag, Hans |
|
2012 |
|
2 |
p. e121-e130 nvt p. |
artikel |
50 |
Overcoming poor permeability: translating permeation enhancers for oral peptide delivery
|
Maher, Sam |
|
2012 |
|
2 |
p. e113-e119 nvt p. |
artikel |
51 |
Overview and comparison of ortholog databases
|
Alexeyenko, Andrey |
|
2006 |
|
2 |
p. 137-143 7 p. |
artikel |
52 |
Peptide and protein transdermal drug delivery
|
Herwadkar, Anushree |
|
2012 |
|
2 |
p. e147-e154 nvt p. |
artikel |
53 |
Peptide scalpels for site-specific dissection of the DNA–protein interface
|
Verzele, Dieter |
|
2010 |
|
2 |
p. e115-e123 nvt p. |
artikel |
54 |
Potential and limitations of genetic manipulation in animals
|
O'Sullivan, Gerard J. |
|
2006 |
|
2 |
p. 173-180 8 p. |
artikel |
55 |
Preclinical in vitro screening assays for drug-like properties
|
Li, Albert P. |
|
2005 |
|
2 |
p. 179-185 7 p. |
artikel |
56 |
Prediction and classification of protein functions
|
Ruepp, Andreas |
|
2006 |
|
2 |
p. 145-151 7 p. |
artikel |
57 |
Prediction of failure load using micro-finite element analysis models: Toward in vivo strength assessment
|
van Lenthe, G. Harry |
|
2006 |
|
2 |
p. 221-229 9 p. |
artikel |
58 |
Proteomic technologies for cancer target validation
|
Jain, K.K. |
|
2004 |
|
2 |
p. 75-78 4 p. |
artikel |
59 |
Recombinant approaches to large polyketide molecules as potential drugs
|
Peirú, Salvador |
|
2010 |
|
2 |
p. e105-e113 nvt p. |
artikel |
60 |
Reverse pharmacology and the de-orphanization of 7TM receptors
|
Kotarsky, Knut |
|
2004 |
|
2 |
p. 99-104 6 p. |
artikel |
61 |
RNA interference as a tool for target validation
|
Pauls, Eduardo |
|
2004 |
|
2 |
p. 135-140 6 p. |
artikel |
62 |
siRNA as a conventional drug in the clinic? Challenges and current technologies
|
Shim, Min Suk |
|
2012 |
|
2 |
p. e167-e173 nvt p. |
artikel |
63 |
siRNAs as potential drugs
|
Wang, Xiaoxia |
|
2010 |
|
2 |
p. e125-e130 nvt p. |
artikel |
64 |
Smart polymers for peptide and protein parenteral sustained delivery
|
Oak, Mayura |
|
2012 |
|
2 |
p. e131-e140 nvt p. |
artikel |
65 |
Synthetic host molecules and sequestrants as therapeutic agents
|
Zhang, Ming-Qiang |
|
2010 |
|
2 |
p. e131-e137 nvt p. |
artikel |
66 |
Tapping, pulling, probing: atomic force microscopy in drug discovery
|
Legleiter, Justin |
|
2004 |
|
2 |
p. 163-169 7 p. |
artikel |
67 |
The innovative use of a large-scale industry biomedical consortium to research the genetic basis of drug induced serious adverse events
|
Holden, Arthur L. |
|
2007 |
|
2 |
p. 75-87 13 p. |
artikel |
68 |
The pharmacology of electrical stimulation in the heart: Where devices meet drugs
|
Krauthamer, Victor |
|
2007 |
|
2 |
p. 63-67 5 p. |
artikel |
69 |
The Predictive Safety Testing Consortium: A synthesis of the goals, challenges and accomplishments of the Critical Path
|
Goodsaid, Federico M. |
|
2007 |
|
2 |
p. 47-50 4 p. |
artikel |
70 |
The role of bioinformatics in target validation
|
Whittaker, Paul A. |
|
2004 |
|
2 |
p. 125-133 9 p. |
artikel |
71 |
The use of amorphous solid dispersions: A formulation strategy to overcome poor solubility and dissolution rate
|
Van den Mooter, Guy |
|
2012 |
|
2 |
p. e79-e85 nvt p. |
artikel |
72 |
The use of micro-CT to study bone architecture dynamics noninvasively
|
van der Linden, Jacqueline C. |
|
2006 |
|
2 |
p. 213-219 7 p. |
artikel |
73 |
The use of nucleic acid tools for target validation in central nervous system therapy
|
Godfray, Jenny |
|
2004 |
|
2 |
p. 85-91 7 p. |
artikel |
74 |
Use of ribozymes in validation of targets involved in tumor progression
|
Zaffaroni, Nadia |
|
2004 |
|
2 |
p. 119-124 6 p. |
artikel |
75 |
Yeast as a budding technology in target validation
|
Bays, Nathan |
|
2004 |
|
2 |
p. 157-162 6 p. |
artikel |
76 |
Yeast as a screening tool
|
Barberis, Alcide |
|
2005 |
|
2 |
p. 187-192 6 p. |
artikel |