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                             78 results found
no title author magazine year volume issue page(s) type
1 A combined experimental and computational study on peptide nucleic acid (PNA) analogues of tumor suppressive miRNA-34a Piacenti, Valerio

91 C p.
article
2 Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells Nepali, Kunal

91 C p.
article
3 An efficient method for the synthesis of novel derivatives 4-{5-[4-(4-amino-5-mercapto-4H-[1,2,4]triazol-3-yl)-phenyl]-3-trifluoromethyl-pyrazol-1-yl}-benzenesulfonamide and their anti-inflammatory potential Mustafa, Ghulam

91 C p.
article
4 Antifungal activity and tautomeric cyclization equilibria of formylphenylboronic acids Borys, Krzysztof M.

91 C p.
article
5 Anti-inflammatory and antiproliferative prenylated carbazole alkaloids from Clausena vestita Liu, Yan-Ping

91 C p.
article
6 Anti-inflammatory spiroaxane and drimane sesquiterpenoids from Talaromyces minioluteus (Penicillium minioluteum) Chen, Chunmei

91 C p.
article
7 Arylboronate prodrugs of doxorubicin as promising chemotherapy for pancreatic cancer Skarbek, Charles

91 C p.
article
8 A solid-phase method for synthesis of dimeric and trimeric ligands: Identification of potent bivalent ligands of 14-3-3σ Lee, Yeongju

91 C p.
article
9 Bioactivatable reductive cleavage of azobenzene for controlling functional dumbbell oligodeoxynucleotides Lei, Huajun

91 C p.
article
10 Bis-coumarins; non-cytotoxic selective urease inhibitors and antiglycation agents Salar, Uzma

91 C p.
article
11 cAMPS derivatives. A minireview over synthetic medicinal chemistry Undheim, Kjell

91 C p.
article
12 Chalcone derivatives and their antibacterial activities: Current development Xu, Man

91 C p.
article
13 Chemical constituents of the root bark of Ulmus davidiana var. japonica and their potential biological activities So, Hae Min

91 C p.
article
14 Chemo-sensitizing activity of natural cadinanes from Heterotheca inuloides in human uterine sarcoma cells and their in silico interaction with ABC transporters Rodríguez-Chávez, José Luis

91 C p.
article
15 Designing of promising medicinal scaffolds for Alzheimer’s disease through enzyme inhibition, lead optimization, molecular docking and dynamic simulation approaches Hassan, Mubashir

91 C p.
article
16 Design, synthesis and antibacterial activity evaluation of moxifloxacin-amide-1,2,3-triazole-isatin hybrids Gao, Feng

91 C p.
article
17 Design, synthesis and biological evaluation of 4-aminoquinoline-guanylthiourea derivatives as antimalarial agents Bhagat, Shweta

91 C p.
article
18 Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors Zhou, Du-Chao

91 C p.
article
19 Design, synthesis and biological evaluation of trinary benzocoumarin-thiazoles-azomethines derivatives as effective and selective inhibitors of alkaline phosphatase Channar, Pervaiz Ali

91 C p.
article
20 Design, synthesis and evaluation of phthalazinone thiohydantoin-based derivative as potent PARP-1 inhibitors Zhong, Yi

91 C p.
article
21 Design, synthesis, anticancer evaluation and docking studies of new pyrimidine derivatives as potent thymidylate synthase inhibitors Amin, Lamia H.T.

91 C p.
article
22 Design, synthesis, biological and in silico evaluation of coumarin-hydrazone derivatives as tubulin targeted antiproliferative agents Govindaiah, Pilli

91 C p.
article
23 Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of phthalimide-sulfonylurea hybrids as PPARγ and SUR agonists El-Zahabi, Mohamed Ayman

91 C p.
article
24 Discovery of Michael acceptor containing 1,4-dihydropyridines as first covalent inhibitors of L-/T-type calcium channels Aygün Cevher, Hande

91 C p.
article
25 Discovery of novel cage-like heterocyclic hybrids as anti-inflammatory agents through the inhibition of nitrite, PGE2 and TNF-α Kumar, Raju Suresh

91 C p.
article
26 Discovery, synthesis and molecular substantiation of N-(benzo[d]thiazol-2-yl)-2-hydroxyquinoline-4-carboxamides as anticancer agents Bindu, B.

91 C p.
article
27 2,5-Disubstituted thiadiazoles as potent β-glucuronidase inhibitors; Synthesis, in vitro and in silico studies Taha, Muhammad

91 C p.
article
28 Editorial Board
91 C p.
article
29 Flavonols and 4-thioflavonols as potential acetylcholinesterase and butyrylcholinesterase inhibitors: Synthesis, structure-activity relationship and molecular docking studies Mughal, Ehsan Ullah

91 C p.
article
30 FtsZ inhibitors as a new genera of antibacterial agents Tripathy, Swayansiddha

91 C p.
article
31 Genetic dereplication of Trichoderma hypoxylon reveals two novel polycyclic lactones Chen, Lin

91 C p.
article
32 Identification of novel peptidomimetics targeting the polo-box domain of polo-like kinase 1 Li, Zhiyan

91 C p.
article
33 Iizukines C−E from a saline soil fungus Aspergillus iizukae Kang, Hui-Hui

91 C p.
article
34 Issue TOC
91 C p.
article
35 Labeling of VEGFR1D2 through oxime ligation De Rosa, Lucia

91 C p.
article
36 Lysosome imaging in cancer cells by pyrene-benzothiazolium dyes: An alternative imaging approach for LAMP-1 expression based visualization methods to avoid background interference Abeywickrama, Chathura S.

91 C p.
article
37 Mechanistic studies on Pyrobaculum calidifontis porphobilinogen synthase (5-aminolevulinic acid dehydratase) Azim, Naseema

91 C p.
article
38 Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer’s disease therapy Malek, Rim

91 C p.
article
39 Natural neuroprotective alkaloids from Stephania japonica (Thunb.) Miers Xiao, Jiao

91 C p.
article
40 New classes of carbazoles as potential multi-functional anti-Alzheimer’s agents Choubdar, Niloufar

91 C p.
article
41 New hexalactone derivatives and a pair of new oxaspiro-carbon epimeric glycosides from the fruits of Illicium lanceolatum Liu, Yang-Lan

91 C p.
article
42 New phenolic cinnamic acid derivatives as selective COX-2 inhibitors. Design, synthesis, biological activity and structure-activity relationships Ribeiro, Daniela

91 C p.
article
43 Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties Erdemir, Fatoş

91 C p.
article
44 Novel steroidal 1,3,4-thiadiazines: Synthesis and biological evaluation in androgen receptor-positive prostate cancer 22Rv1 cells Komendantova, Anna S.

91 C p.
article
45 N-substituted noscapine derivatives as new antiprotozoal agents: Synthesis, antiparasitic activity and molecular docking study Babanezhad Harikandei, Kosar

91 C p.
article
46 One-step immobilization and purification of genetic engineering CBD fusion EndoS on cellulose for antibodies Fc-glycan remodeling Zhao, Kai

91 C p.
article
47 Optimization of a single HPLC-PDA method for quantifying Metformin, Gliclazide, Pioglitazone, Dapagliflozin, Empagliflozin, Saxagliptin, Linagliptin and Teneligliptin using central composite design Kant, Ravi

91 C p.
article
48 Phytoscreening of Vochysiaceae species: Molecular identification by HPLC-ESI-MS/MS and evaluating of their antioxidant activity and inhibitory potential against human α-amylase and protein glycation Franco, R.R.

91 C p.
article
49 Revealing synergistic mechanism of multiple components in Stauntonia brachyanthera Hand.-Mazz. for gout by virtual screening and system pharmacological approach Hua, Qiong-qiong

91 C p.
article
50 Searching new structural scaffolds for BRAF inhibitors. An integrative study using theoretical and experimental techniques Campos, Ludmila E.

91 C p.
article
51 Small molecule HDAC inhibitors: Promising agents for breast cancer treatment Huang, Meiling

91 C p.
article
52 Strategy and validation of a structure-based method for the discovery of selective inhibitors of PAK isoforms and the evaluation of their anti-cancer activity Song, Pei-Lu

91 C p.
article
53 Structural modifications and in vitro pharmacological evaluation of 4-pyridyl-piperazine derivatives as an active and selective histamine H3 receptor ligands Szczepańska, Katarzyna

91 C p.
article
54 1,8-Substituted anthraquinones, anthrones and bianthrones as potential non-azole leads against fungal infections Jalab, Murhaf

91 C p.
article
55 Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors Chiaramonte, Niccolò

91 C p.
article
56 Synthesis and application of a “turn on” fluorescent probe for glutathione based on a copper complex of coumarin hydrazide Schiff base derivative He, Guangjie

91 C p.
article
57 Synthesis and biological evaluation of bergenin-1,2,3-triazole hybrids as novel class of anti-mitotic agents Pavan Kumar, P.

91 C p.
article
58 Synthesis, biological evaluation and molecular docking studies of bis-chalcone derivatives as xanthine oxidase inhibitors and anticancer agents Burmaoglu, Serdar

91 C p.
article
59 Synthesis, in silico and in vitro studies of new 1,4-dihydropiridine derivatives for antitumor and P-glycoprotein inhibitory activity Mollazadeh, Shirin

91 C p.
article
60 Synthesis, in-vitro α-glucosidase inhibition, antioxidant, in-vivo antidiabetic and molecular docking studies of pyrrolidine-2,5-dione and thiazolidine-2,4-dione derivatives Hussain, Fida

91 C p.
article
61 Synthesis, molecular docking analysis and carbonic anhydrase I-II inhibitory evaluation of new sulfonamide derivatives Sağlık, Begüm Nurpelin

91 C p.
article
62 Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors Makhaeva, Galina F.

91 C p.
article
63 Synthesis of 3-indolylmethyl substituted (pyrazolo/benzo)triazinone derivatives under Pd/Cu-catalysis: Identification of potent inhibitors of chorismate mutase (CM) Reddy, Gangireddy Sujeevan

91 C p.
article
64 Synthesis of new arylhydrazide bearing Schiff bases/thiazolidinone: α-Amylase, urease activities and their molecular docking studies Rahim, Fazal

91 C p.
article
65 Synthesis of novel methyl jasmonate derivatives and evaluation of their biological activity in various cancer cell lines Sucu, Bilgesu Onur

91 C p.
article
66 Synthesis of novel (R)-4-fluorophenyl-1H-1,2,3-triazoles: A new class of α-glucosidase inhibitors Avula, Satya Kumar

91 C p.
article
67 Synthesis, physicochemical and biological evaluation of tacrine derivative labeled with technetium-99m and gallium-68 as a prospective diagnostic tool for early diagnosis of Alzheimer’s disease Gniazdowska, Ewa

91 C p.
article
68 The 5-hydrazino-3-methylisothiazole-4-carboxylic acid, its new 5-substituted derivatives and their antiproliferative activity Jęśkowiak, Izabela

91 C p.
article
69 The influence of cationic dendrimers on antibacterial activity of phage endolysin against P. aeruginosa cells Ciepluch, Karol

91 C p.
article
70 The novel economical synthesis and antimicrobial activity of a trithiocarbonate derivative Mabkhot, Yahia N.

91 C p.
article
71 Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities Abdellatif, Khaled R.A.

91 C p.
article
72 Three new cyclopiane-type diterpenes from a deep-sea derived fungus Penicillium sp. YPGA11 and their effects against human esophageal carcinoma cells Cheng, Zhongbin

91 C p.
article
73 Tyrosine-based asymmetric urea ligand for prostate carcinoma: Tuning biological efficacy through in silico studies Sengupta, Sagnik

91 C p.
article
74 Tyrosol from marine Fungi, a novel Quorum sensing inhibitor against Chromobacterium violaceum and Pseudomonas aeruginosa Chang, Aiping

91 C p.
article
75 Ugi efficient synthesis, biological evaluation and molecular docking of coumarin-quinoline hybrids as apoptotic agents through mitochondria-related pathways Taheri, Salman

91 C p.
article
76 Ureidobenzenesulfonamides as efficient inhibitors of carbonic anhydrase II Serbian, Immo

91 C p.
article
77 Utilization of tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidinone as a cap moiety in design of novel histone deacetylase inhibitors Mohamed, Mamdouh F.A.

91 C p.
article
78 Water soluble thioglycosylated BODIPYs for mitochondria targeted cytotoxicity Kesavan, Praseetha E.

91 C p.
article
                             78 results found
 
 Koninklijke Bibliotheek - National Library of the Netherlands