nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
Alternative business models for drug discovery
|
Bunin, Barry A. |
|
2011 |
|
15-16 |
p. 643-645 3 p. |
artikel |
2 |
An early history of the molecular modeling industry
|
Richon, Allen B. |
|
2008 |
|
15-16 |
p. 659-664 6 p. |
artikel |
3 |
A new paradigm for protein kinase inhibition: blocking phosphorylation without directly targeting ATP binding
|
Bogoyevitch, Marie A |
|
2007 |
|
15-16 |
p. 622-633 12 p. |
artikel |
4 |
Animal models of asthma: value, limitations and opportunities for alternative approaches
|
Holmes, Anthony M. |
|
2011 |
|
15-16 |
p. 659-670 12 p. |
artikel |
5 |
A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #2: protocol optimization and best practices
|
Schwarz, Adam J. |
|
2011 |
|
15-16 |
p. 671-682 12 p. |
artikel |
6 |
August Diary
|
|
|
2007 |
|
15-16 |
p. 682- 1 p. |
artikel |
7 |
Biaryl piperidine melanin-concentrating hormone-1 receptor antagonists for obesity
|
Edwards, Paul |
|
2006 |
|
15-16 |
p. 770-771 2 p. |
artikel |
8 |
Biologics: the next generation of analgesic drugs?
|
Chessell, Iain P. |
|
2012 |
|
15-16 |
p. 875-879 5 p. |
artikel |
9 |
Biopharma business models in Canada
|
March-Chordà, I. |
|
2011 |
|
15-16 |
p. 654-658 5 p. |
artikel |
10 |
Can Drosophila melanogaster represent a model system for the detection of reproductive adverse drug reactions?
|
Avanesian, Agnesa |
|
2009 |
|
15-16 |
p. 761-766 6 p. |
artikel |
11 |
Can network pharmacology rescue neutraceutical cancer research?
|
Azmi, Asfar S. |
|
2012 |
|
15-16 |
p. 807-809 3 p. |
artikel |
12 |
Can we estimate the accuracy of ADME–Tox predictions?
|
Tetko, Igor V. |
|
2006 |
|
15-16 |
p. 700-707 8 p. |
artikel |
13 |
Cell culture metabolomics: applications and future directions
|
Čuperlović-Culf, Miroslava |
|
2010 |
|
15-16 |
p. 610-621 12 p. |
artikel |
14 |
Cell-penetrating peptides: classes, origin, and current landscape
|
Milletti, Francesca |
|
2012 |
|
15-16 |
p. 850-860 11 p. |
artikel |
15 |
Characteristics of rare disease marketing applications associated with FDA product approvals 2006–2010
|
Pariser, Anne R. |
|
2012 |
|
15-16 |
p. 898-904 7 p. |
artikel |
16 |
Chemistry strategies in early drug discovery: an overview of recent trends
|
Colombo, Matteo |
|
2008 |
|
15-16 |
p. 677-684 8 p. |
artikel |
17 |
Clinical research in China and India: a paradigm shift in drug development
|
Singh, Romi |
|
2006 |
|
15-16 |
p. 675-676 2 p. |
artikel |
18 |
Computational mapping tools for drug discovery
|
Ivanenkov, Yan A. |
|
2009 |
|
15-16 |
p. 767-775 9 p. |
artikel |
19 |
Contents
|
|
|
2009 |
|
15-16 |
p. iii- 1 p. |
artikel |
20 |
Contents
|
|
|
2009 |
|
15-16 |
p. i- 1 p. |
artikel |
21 |
Contents
|
|
|
2007 |
|
15-16 |
p. iii- 1 p. |
artikel |
22 |
Contents
|
|
|
2008 |
|
15-16 |
p. iii- 1 p. |
artikel |
23 |
Contents
|
|
|
2008 |
|
15-16 |
p. i- 1 p. |
artikel |
24 |
Contents
|
|
|
2013 |
|
15-16 |
p. iii- 1 p. |
artikel |
25 |
Contents
|
|
|
2013 |
|
15-16 |
p. i- 1 p. |
artikel |
26 |
Contents
|
|
|
2012 |
|
15-16 |
p. i- 1 p. |
artikel |
27 |
Contents
|
|
|
2012 |
|
15-16 |
p. iii- 1 p. |
artikel |
28 |
Contents page 1
|
|
|
2010 |
|
15-16 |
p. i- 1 p. |
artikel |
29 |
Contents page 2
|
|
|
2010 |
|
15-16 |
p. iii- 1 p. |
artikel |
30 |
Contents page 2
|
|
|
2011 |
|
15-16 |
p. iii- 1 p. |
artikel |
31 |
Contents page 1
|
|
|
2011 |
|
15-16 |
p. i- 1 p. |
artikel |
32 |
Current endovascular treatment of acute stroke and future aspects
|
Killer, Monika |
|
2010 |
|
15-16 |
p. 640-647 8 p. |
artikel |
33 |
Current status and future direction of the molecular modeling industry
|
Richon, Allen B. |
|
2008 |
|
15-16 |
p. 665-669 5 p. |
artikel |
34 |
Current status of liposomal porphyrinoid photosensitizers
|
Skupin-Mrugalska, Paulina |
|
2013 |
|
15-16 |
p. 776-784 9 p. |
artikel |
35 |
Cysteamine: an old drug with new potential
|
Besouw, Martine |
|
2013 |
|
15-16 |
p. 785-792 8 p. |
artikel |
36 |
DARPins: A new generation of protein therapeutics
|
Stumpp, Michael T. |
|
2008 |
|
15-16 |
p. 695-701 7 p. |
artikel |
37 |
Data structures and computational tools for the extraction of SAR information from large compound sets
|
Wawer, Mathias |
|
2010 |
|
15-16 |
p. 630-639 10 p. |
artikel |
38 |
Denmark: going from strength to strength
|
Jensen, Louise Wendt |
|
2008 |
|
15-16 |
p. 637-639 3 p. |
artikel |
39 |
Design and synthesis of a novel DNA-encoded chemical library
|
Edwards, Paul |
|
2010 |
|
15-16 |
p. 690-691 2 p. |
artikel |
40 |
Designed multiple ligands in metabolic disease research: from concept to platform
|
Gattrell, W. |
|
2013 |
|
15-16 |
p. 692-696 5 p. |
artikel |
41 |
Diary Vol/ISS 11/15
|
|
|
2006 |
|
15-16 |
p. 772- 1 p. |
artikel |
42 |
DNA demethylases: a new epigenetic frontier in drug discovery
|
Carey, Nessa |
|
2011 |
|
15-16 |
p. 683-690 8 p. |
artikel |
43 |
DNA polymerase beta (pol β) inhibitors: A comprehensive overview
|
Barakat, Khaled H. |
|
2012 |
|
15-16 |
p. 913-920 8 p. |
artikel |
44 |
Drug discovery chemistry: a primer for the non-specialist
|
Jordan, Allan M. |
|
2009 |
|
15-16 |
p. 731-744 14 p. |
artikel |
45 |
Drug discovery in the extracellular matrix
|
Huxley-Jones, Julie |
|
2008 |
|
15-16 |
p. 685-694 10 p. |
artikel |
46 |
Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery
|
Pérot, Stéphanie |
|
2010 |
|
15-16 |
p. 656-667 12 p. |
artikel |
47 |
Drug metabolism in the paediatric population and in the elderly
|
Benedetti, Margherita Strolin |
|
2007 |
|
15-16 |
p. 599-610 12 p. |
artikel |
48 |
Drug resistance: a growing problem
|
Peet, Norton P. |
|
2010 |
|
15-16 |
p. 583-586 4 p. |
artikel |
49 |
Editorial Board
|
|
|
2007 |
|
15-16 |
p. v- 1 p. |
artikel |
50 |
ELN implementation challenges
|
Drake, David J. |
|
2007 |
|
15-16 |
p. 647-649 3 p. |
artikel |
51 |
Erratum to: Heparin/heparan sulphate-based drugs
|
Gandhi, Neha S. |
|
2011 |
|
15-16 |
p. 741- 1 p. |
artikel |
52 |
Evaluation of novel drugs using fMRI in early-phase clinical trials: safety monitoring
|
George, Edward |
|
2010 |
|
15-16 |
p. 684-689 6 p. |
artikel |
53 |
Evidence-based approach to assess passive diffusion and carrier-mediated drug transport
|
Di, Li |
|
2012 |
|
15-16 |
p. 905-912 8 p. |
artikel |
54 |
Ezetimibe as a potential treatment for non-alcoholic fatty liver disease: is the intestine a modulator of hepatic insulin sensitivity and hepatic fat accumulation?
|
Ahmed, Mohamed H. |
|
2010 |
|
15-16 |
p. 590-595 6 p. |
artikel |
55 |
FDA-approved drug labeling for the study of drug-induced liver injury
|
Chen, Minjun |
|
2011 |
|
15-16 |
p. 697-703 7 p. |
artikel |
56 |
Fluorine local environment: from screening to drug design
|
Vulpetti, Anna |
|
2012 |
|
15-16 |
p. 890-897 8 p. |
artikel |
57 |
Following up high-throughput screening with parallel chemistry for the generation of actives against biological targets
|
Edwards, Paul |
|
2008 |
|
15-16 |
p. 723-725 3 p. |
artikel |
58 |
Follow-on drugs: How far should chemists look?
|
Giordanetto, Fabrizio |
|
2011 |
|
15-16 |
p. 722-732 11 p. |
artikel |
59 |
French/European academic compound library initiative
|
Hibert, Marcel F. |
|
2009 |
|
15-16 |
p. 723-725 3 p. |
artikel |
60 |
Getting physical in drug discovery: a contemporary perspective on solubility and hydrophobicity
|
Hill, Alan P. |
|
2010 |
|
15-16 |
p. 648-655 8 p. |
artikel |
61 |
Hammerhead ribozymes in therapeutic target discovery and validation
|
Tedeschi, Lorena |
|
2009 |
|
15-16 |
p. 776-783 8 p. |
artikel |
62 |
Hit discovery and hit-to-lead approaches
|
Keserű, György M. |
|
2006 |
|
15-16 |
p. 741-748 8 p. |
artikel |
63 |
‘Hot’ bacterial viruses shed more light on genetic instability
|
Demidov, Vadim V. |
|
2008 |
|
15-16 |
p. 726-727 2 p. |
artikel |
64 |
HTS technologies in biopharmaceutical discovery
|
Wu, Ge |
|
2006 |
|
15-16 |
p. 718-724 7 p. |
artikel |
65 |
Identification of drugs that interact with herbs in drug development
|
Zhou, Shu-Feng |
|
2007 |
|
15-16 |
p. 664-673 10 p. |
artikel |
66 |
Immunogenicity of protein therapeutics and the interplay between tolerance and antibody responses
|
Barbosa, Maria D.F.S. |
|
2007 |
|
15-16 |
p. 674-681 8 p. |
artikel |
67 |
Increasing the reliability of protein interactomes
|
Chua, Hon Nian |
|
2008 |
|
15-16 |
p. 652-658 7 p. |
artikel |
68 |
Inhibition of proteases as a novel therapeutic strategy in the treatment of metabolic, inflammatory and functional diseases of the gastrointestinal tract
|
Sałaga, Maciej |
|
2013 |
|
15-16 |
p. 708-715 8 p. |
artikel |
69 |
Inorganic hollow nanoparticles and nanotubes in nanomedicine
|
Son, Sang Jun |
|
2007 |
|
15-16 |
p. 650-656 7 p. |
artikel |
70 |
Inorganic hollow nanoparticles and nanotubes in nanomedicine
|
Son, Sang Jun |
|
2007 |
|
15-16 |
p. 657-663 7 p. |
artikel |
71 |
Insight into the structural determinants for selective inhibition of matrix metalloproteinases
|
Pirard, Bernard |
|
2007 |
|
15-16 |
p. 640-646 7 p. |
artikel |
72 |
Is autologous chondrocyte implantation (ACI) an adequate treatment option for repair of cartilage defects in paediatric patients?
|
Kaszkin-Bettag, Marietta |
|
2013 |
|
15-16 |
p. 740-747 8 p. |
artikel |
73 |
Major advances in the development of histamine H4 receptor ligands
|
Smits, Rogier A. |
|
2009 |
|
15-16 |
p. 745-753 9 p. |
artikel |
74 |
Matched Molecular Pair Analysis in drug discovery
|
Dossetter, Alexander G. |
|
2013 |
|
15-16 |
p. 724-731 8 p. |
artikel |
75 |
Memo to the FDA and ICH: appeal for in vivo drug target identification and target pharmacokinetics
|
Stumpf, Walter E |
|
2007 |
|
15-16 |
p. 594-598 5 p. |
artikel |
76 |
Methods for mining HTS data
|
Harper, Gavin |
|
2006 |
|
15-16 |
p. 694-699 6 p. |
artikel |
77 |
Microtissue size and hypoxia in HTS with 3D cultures
|
Asthana, Amish |
|
2012 |
|
15-16 |
p. 810-817 8 p. |
artikel |
78 |
Model-based drug discovery: implementation and impact
|
Visser, Sandra A.G. |
|
2013 |
|
15-16 |
p. 764-775 12 p. |
artikel |
79 |
Modulating TNF-α signaling with natural products
|
Paul, Atish T. |
|
2006 |
|
15-16 |
p. 725-732 8 p. |
artikel |
80 |
Molecular clinical safety intelligence: a system for bridging clinically focused safety knowledge to early-stage drug discovery – the GSK experience
|
Vanderwall, Dana E. |
|
2011 |
|
15-16 |
p. 646-653 8 p. |
artikel |
81 |
Molecular simulations of carbohydrates and protein–carbohydrate interactions: motivation, issues and prospects
|
Fadda, Elisa |
|
2010 |
|
15-16 |
p. 596-609 14 p. |
artikel |
82 |
Molecular understanding of curcumin in diabetic nephropathy
|
Soetikno, Vivian |
|
2013 |
|
15-16 |
p. 756-763 8 p. |
artikel |
83 |
mTOR as a multifunctional therapeutic target in HIV infection
|
Nicoletti, Ferdinando |
|
2011 |
|
15-16 |
p. 715-721 7 p. |
artikel |
84 |
Multipotent antioxidants: from screening to design
|
Zhang, Hong-Yu |
|
2006 |
|
15-16 |
p. 749-754 6 p. |
artikel |
85 |
Needed: system dynamics for the drug discovery process
|
Sirois, Suzanne |
|
2008 |
|
15-16 |
p. 708-715 8 p. |
artikel |
86 |
Network analysis has diverse roles in drug discovery
|
Hasan, Samiul |
|
2012 |
|
15-16 |
p. 869-874 6 p. |
artikel |
87 |
New Court guidance on repackaging of parallel traded products
|
Wright, Elisabethann |
|
2007 |
|
15-16 |
p. 591-593 3 p. |
artikel |
88 |
New tools for functional genomic analysis
|
Chen, Xin |
|
2009 |
|
15-16 |
p. 754-760 7 p. |
artikel |
89 |
New Zealand: unique biodiversity and world-class science converge
|
Boalch, Chris |
|
2006 |
|
15-16 |
p. 677-680 4 p. |
artikel |
90 |
Non-peptidyl insulin mimetics as a potential antidiabetic agent
|
Nankar, Rakesh P. |
|
2013 |
|
15-16 |
p. 748-755 8 p. |
artikel |
91 |
Orphan drug development across Europe: bottlenecks and opportunities
|
Heemstra, Harald E. |
|
2008 |
|
15-16 |
p. 670-676 7 p. |
artikel |
92 |
Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only
|
Kell, Douglas B. |
|
2011 |
|
15-16 |
p. 704-714 11 p. |
artikel |
93 |
Pharmacokinetics and the drug–target residence time concept
|
Dahl, Göran |
|
2013 |
|
15-16 |
p. 697-707 11 p. |
artikel |
94 |
Physiological, pathological and potential therapeutic roles of adipokines
|
Falcão-Pires, Inês |
|
2012 |
|
15-16 |
p. 880-889 10 p. |
artikel |
95 |
Potentiation strategies of dendritic cell-based antitumor vaccines: combinational therapy takes the front seat
|
Torabi-Rahvar, Monireh |
|
2011 |
|
15-16 |
p. 733-740 8 p. |
artikel |
96 |
Preclinical assessment of cardiac toxicity
|
Kettenhofen, Ralf |
|
2008 |
|
15-16 |
p. 702-707 6 p. |
artikel |
97 |
Progress and problems in the exploration of therapeutic targets
|
|
|
2006 |
|
15-16 |
p. 717- 1 p. |
artikel |
98 |
Progressing preclinical drug candidates: strategies on preclinical safety studies and the quest for adequate exposure
|
Higgins, John |
|
2012 |
|
15-16 |
p. 828-836 9 p. |
artikel |
99 |
Progress in the development of peroxide-based anti-parasitic agents
|
Muraleedharan, K.M. |
|
2009 |
|
15-16 |
p. 793-803 11 p. |
artikel |
100 |
Pyrimidin-4-yl phenols as anti-infective agents
|
Edwards, Paul |
|
2006 |
|
15-16 |
p. 768-769 2 p. |
artikel |
101 |
R&D investments for neglected diseases can be sensitive to the economic goal of pharmaceutical companies
|
Dimitri, Nicola |
|
2012 |
|
15-16 |
p. 818-823 6 p. |
artikel |
102 |
Recent advances in glucokinase activators for the treatment of type 2 diabetes
|
Pal, Manojit |
|
2009 |
|
15-16 |
p. 784-792 9 p. |
artikel |
103 |
Recent PDE4 inhibitor clinical candidates
|
Yeung, Kap-Sun |
|
2009 |
|
15-16 |
p. 812-813 2 p. |
artikel |
104 |
Relaxin family peptide receptors – from orphans to therapeutic targets
|
van der Westhuizen, Emma T. |
|
2008 |
|
15-16 |
p. 640-651 12 p. |
artikel |
105 |
Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases
|
Dong, Ming |
|
2010 |
|
15-16 |
p. 622-629 8 p. |
artikel |
106 |
ROCK: the Roche medicinal chemistry knowledge application – design, use and impact
|
Mayweg, Alexander |
|
2011 |
|
15-16 |
p. 691-696 6 p. |
artikel |
107 |
Screening the receptorome: an efficient approach for drug discovery and target validation
|
Strachan, Ryan T. |
|
2006 |
|
15-16 |
p. 708-716 9 p. |
artikel |
108 |
Seeding drug discovery: integrating telomerase cancer biology and cellular senescence to uncover new therapeutic opportunities in targeting cancer stem cells
|
Keith, W Nicol |
|
2007 |
|
15-16 |
p. 611-621 11 p. |
artikel |
109 |
Strategic alliances and market risk
|
Havenaar, Matthias |
|
2012 |
|
15-16 |
p. 824-827 4 p. |
artikel |
110 |
Strategic groups in the biopharmaceutical industry: implications for performance
|
Erden, Zeynep |
|
2009 |
|
15-16 |
p. 726-730 5 p. |
artikel |
111 |
Strategies to support drug discovery through integration of systems and data
|
Waller, Chris L. |
|
2007 |
|
15-16 |
p. 634-639 6 p. |
artikel |
112 |
Synthetic library design
|
Huwe, Christoph M. |
|
2006 |
|
15-16 |
p. 763-767 5 p. |
artikel |
113 |
Systematic characterization of structure–activity relationships and ADMET compliance: a case study
|
Yongye, Austin B. |
|
2013 |
|
15-16 |
p. 732-739 8 p. |
artikel |
114 |
Targeting atypical trypanosomatid DNA topoisomerase I
|
Balaña-Fouce, Rafael |
|
2006 |
|
15-16 |
p. 733-740 8 p. |
artikel |
115 |
Targeting mTOR as a novel therapeutic strategy for traumatic CNS injuries
|
Arachchige Don, Aruni S. |
|
2012 |
|
15-16 |
p. 861-868 8 p. |
artikel |
116 |
The challenges of product development and commercialization in a convergence technology world: focus on regenerative medicine
|
Tozer, Dean |
|
2010 |
|
15-16 |
p. 587-589 3 p. |
artikel |
117 |
The Drug Discovery Portal: a resource to enhance drug discovery from academia
|
Clark, Rachel L. |
|
2010 |
|
15-16 |
p. 679-683 5 p. |
artikel |
118 |
The future is here: tumour profiling in day-to-day clinical practice
|
Lemech, Charlotte R. |
|
2013 |
|
15-16 |
p. 689-691 3 p. |
artikel |
119 |
The impact of interferon-β treatment on the blood–brain barrier
|
Kraus, Jörg |
|
2006 |
|
15-16 |
p. 755-762 8 p. |
artikel |
120 |
Therapeutic strategies for the treatment of stroke
|
Green, A. Richard |
|
2006 |
|
15-16 |
p. 681-693 13 p. |
artikel |
121 |
The solution-phase design and synthesis of libraries for the discovery of CNS active substances
|
Edwards, Paul John |
|
2011 |
|
15-16 |
p. 742-744 3 p. |
artikel |
122 |
The Tox21 robotic platform for the assessment of environmental chemicals – from vision to reality
|
Attene-Ramos, Matias S. |
|
2013 |
|
15-16 |
p. 716-723 8 p. |
artikel |
123 |
The value of proteasome inhibition in cancer
|
Cvek, Boris |
|
2008 |
|
15-16 |
p. 716-722 7 p. |
artikel |
124 |
Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward?
|
Patwardhan, Bhushan |
|
2009 |
|
15-16 |
p. 804-811 8 p. |
artikel |
125 |
Translation of drug effects from experimental models of neuropathic pain and analgesia to humans
|
Taneja, Amit |
|
2012 |
|
15-16 |
p. 837-849 13 p. |
artikel |
126 |
What made sesquiterpene lactones reach cancer clinical trials?
|
Ghantous, Akram |
|
2010 |
|
15-16 |
p. 668-678 11 p. |
artikel |