Digitale Bibliotheek
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                             126 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Alternative business models for drug discovery Bunin, Barry A.
2011
15-16 p. 643-645
3 p.
artikel
2 An early history of the molecular modeling industry Richon, Allen B.
2008
15-16 p. 659-664
6 p.
artikel
3 A new paradigm for protein kinase inhibition: blocking phosphorylation without directly targeting ATP binding Bogoyevitch, Marie A
2007
15-16 p. 622-633
12 p.
artikel
4 Animal models of asthma: value, limitations and opportunities for alternative approaches Holmes, Anthony M.
2011
15-16 p. 659-670
12 p.
artikel
5 A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #2: protocol optimization and best practices Schwarz, Adam J.
2011
15-16 p. 671-682
12 p.
artikel
6 August Diary 2007
15-16 p. 682-
1 p.
artikel
7 Biaryl piperidine melanin-concentrating hormone-1 receptor antagonists for obesity Edwards, Paul
2006
15-16 p. 770-771
2 p.
artikel
8 Biologics: the next generation of analgesic drugs? Chessell, Iain P.
2012
15-16 p. 875-879
5 p.
artikel
9 Biopharma business models in Canada March-Chordà, I.
2011
15-16 p. 654-658
5 p.
artikel
10 Can Drosophila melanogaster represent a model system for the detection of reproductive adverse drug reactions? Avanesian, Agnesa
2009
15-16 p. 761-766
6 p.
artikel
11 Can network pharmacology rescue neutraceutical cancer research? Azmi, Asfar S.
2012
15-16 p. 807-809
3 p.
artikel
12 Can we estimate the accuracy of ADME–Tox predictions? Tetko, Igor V.
2006
15-16 p. 700-707
8 p.
artikel
13 Cell culture metabolomics: applications and future directions Čuperlović-Culf, Miroslava
2010
15-16 p. 610-621
12 p.
artikel
14 Cell-penetrating peptides: classes, origin, and current landscape Milletti, Francesca
2012
15-16 p. 850-860
11 p.
artikel
15 Characteristics of rare disease marketing applications associated with FDA product approvals 2006–2010 Pariser, Anne R.
2012
15-16 p. 898-904
7 p.
artikel
16 Chemistry strategies in early drug discovery: an overview of recent trends Colombo, Matteo
2008
15-16 p. 677-684
8 p.
artikel
17 Clinical research in China and India: a paradigm shift in drug development Singh, Romi
2006
15-16 p. 675-676
2 p.
artikel
18 Computational mapping tools for drug discovery Ivanenkov, Yan A.
2009
15-16 p. 767-775
9 p.
artikel
19 Contents 2009
15-16 p. iii-
1 p.
artikel
20 Contents 2009
15-16 p. i-
1 p.
artikel
21 Contents 2007
15-16 p. iii-
1 p.
artikel
22 Contents 2008
15-16 p. iii-
1 p.
artikel
23 Contents 2008
15-16 p. i-
1 p.
artikel
24 Contents 2013
15-16 p. iii-
1 p.
artikel
25 Contents 2013
15-16 p. i-
1 p.
artikel
26 Contents 2012
15-16 p. i-
1 p.
artikel
27 Contents 2012
15-16 p. iii-
1 p.
artikel
28 Contents page 1 2010
15-16 p. i-
1 p.
artikel
29 Contents page 2 2010
15-16 p. iii-
1 p.
artikel
30 Contents page 2 2011
15-16 p. iii-
1 p.
artikel
31 Contents page 1 2011
15-16 p. i-
1 p.
artikel
32 Current endovascular treatment of acute stroke and future aspects Killer, Monika
2010
15-16 p. 640-647
8 p.
artikel
33 Current status and future direction of the molecular modeling industry Richon, Allen B.
2008
15-16 p. 665-669
5 p.
artikel
34 Current status of liposomal porphyrinoid photosensitizers Skupin-Mrugalska, Paulina
2013
15-16 p. 776-784
9 p.
artikel
35 Cysteamine: an old drug with new potential Besouw, Martine
2013
15-16 p. 785-792
8 p.
artikel
36 DARPins: A new generation of protein therapeutics Stumpp, Michael T.
2008
15-16 p. 695-701
7 p.
artikel
37 Data structures and computational tools for the extraction of SAR information from large compound sets Wawer, Mathias
2010
15-16 p. 630-639
10 p.
artikel
38 Denmark: going from strength to strength Jensen, Louise Wendt
2008
15-16 p. 637-639
3 p.
artikel
39 Design and synthesis of a novel DNA-encoded chemical library Edwards, Paul
2010
15-16 p. 690-691
2 p.
artikel
40 Designed multiple ligands in metabolic disease research: from concept to platform Gattrell, W.
2013
15-16 p. 692-696
5 p.
artikel
41 Diary Vol/ISS 11/15 2006
15-16 p. 772-
1 p.
artikel
42 DNA demethylases: a new epigenetic frontier in drug discovery Carey, Nessa
2011
15-16 p. 683-690
8 p.
artikel
43 DNA polymerase beta (pol β) inhibitors: A comprehensive overview Barakat, Khaled H.
2012
15-16 p. 913-920
8 p.
artikel
44 Drug discovery chemistry: a primer for the non-specialist Jordan, Allan M.
2009
15-16 p. 731-744
14 p.
artikel
45 Drug discovery in the extracellular matrix Huxley-Jones, Julie
2008
15-16 p. 685-694
10 p.
artikel
46 Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery Pérot, Stéphanie
2010
15-16 p. 656-667
12 p.
artikel
47 Drug metabolism in the paediatric population and in the elderly Benedetti, Margherita Strolin
2007
15-16 p. 599-610
12 p.
artikel
48 Drug resistance: a growing problem Peet, Norton P.
2010
15-16 p. 583-586
4 p.
artikel
49 Editorial Board 2007
15-16 p. v-
1 p.
artikel
50 ELN implementation challenges Drake, David J.
2007
15-16 p. 647-649
3 p.
artikel
51 Erratum to: Heparin/heparan sulphate-based drugs Gandhi, Neha S.
2011
15-16 p. 741-
1 p.
artikel
52 Evaluation of novel drugs using fMRI in early-phase clinical trials: safety monitoring George, Edward
2010
15-16 p. 684-689
6 p.
artikel
53 Evidence-based approach to assess passive diffusion and carrier-mediated drug transport Di, Li
2012
15-16 p. 905-912
8 p.
artikel
54 Ezetimibe as a potential treatment for non-alcoholic fatty liver disease: is the intestine a modulator of hepatic insulin sensitivity and hepatic fat accumulation? Ahmed, Mohamed H.
2010
15-16 p. 590-595
6 p.
artikel
55 FDA-approved drug labeling for the study of drug-induced liver injury Chen, Minjun
2011
15-16 p. 697-703
7 p.
artikel
56 Fluorine local environment: from screening to drug design Vulpetti, Anna
2012
15-16 p. 890-897
8 p.
artikel
57 Following up high-throughput screening with parallel chemistry for the generation of actives against biological targets Edwards, Paul
2008
15-16 p. 723-725
3 p.
artikel
58 Follow-on drugs: How far should chemists look? Giordanetto, Fabrizio
2011
15-16 p. 722-732
11 p.
artikel
59 French/European academic compound library initiative Hibert, Marcel F.
2009
15-16 p. 723-725
3 p.
artikel
60 Getting physical in drug discovery: a contemporary perspective on solubility and hydrophobicity Hill, Alan P.
2010
15-16 p. 648-655
8 p.
artikel
61 Hammerhead ribozymes in therapeutic target discovery and validation Tedeschi, Lorena
2009
15-16 p. 776-783
8 p.
artikel
62 Hit discovery and hit-to-lead approaches Keserű, György M.
2006
15-16 p. 741-748
8 p.
artikel
63 ‘Hot’ bacterial viruses shed more light on genetic instability Demidov, Vadim V.
2008
15-16 p. 726-727
2 p.
artikel
64 HTS technologies in biopharmaceutical discovery Wu, Ge
2006
15-16 p. 718-724
7 p.
artikel
65 Identification of drugs that interact with herbs in drug development Zhou, Shu-Feng
2007
15-16 p. 664-673
10 p.
artikel
66 Immunogenicity of protein therapeutics and the interplay between tolerance and antibody responses Barbosa, Maria D.F.S.
2007
15-16 p. 674-681
8 p.
artikel
67 Increasing the reliability of protein interactomes Chua, Hon Nian
2008
15-16 p. 652-658
7 p.
artikel
68 Inhibition of proteases as a novel therapeutic strategy in the treatment of metabolic, inflammatory and functional diseases of the gastrointestinal tract Sałaga, Maciej
2013
15-16 p. 708-715
8 p.
artikel
69 Inorganic hollow nanoparticles and nanotubes in nanomedicine Son, Sang Jun
2007
15-16 p. 650-656
7 p.
artikel
70 Inorganic hollow nanoparticles and nanotubes in nanomedicine Son, Sang Jun
2007
15-16 p. 657-663
7 p.
artikel
71 Insight into the structural determinants for selective inhibition of matrix metalloproteinases Pirard, Bernard
2007
15-16 p. 640-646
7 p.
artikel
72 Is autologous chondrocyte implantation (ACI) an adequate treatment option for repair of cartilage defects in paediatric patients? Kaszkin-Bettag, Marietta
2013
15-16 p. 740-747
8 p.
artikel
73 Major advances in the development of histamine H4 receptor ligands Smits, Rogier A.
2009
15-16 p. 745-753
9 p.
artikel
74 Matched Molecular Pair Analysis in drug discovery Dossetter, Alexander G.
2013
15-16 p. 724-731
8 p.
artikel
75 Memo to the FDA and ICH: appeal for in vivo drug target identification and target pharmacokinetics Stumpf, Walter E
2007
15-16 p. 594-598
5 p.
artikel
76 Methods for mining HTS data Harper, Gavin
2006
15-16 p. 694-699
6 p.
artikel
77 Microtissue size and hypoxia in HTS with 3D cultures Asthana, Amish
2012
15-16 p. 810-817
8 p.
artikel
78 Model-based drug discovery: implementation and impact Visser, Sandra A.G.
2013
15-16 p. 764-775
12 p.
artikel
79 Modulating TNF-α signaling with natural products Paul, Atish T.
2006
15-16 p. 725-732
8 p.
artikel
80 Molecular clinical safety intelligence: a system for bridging clinically focused safety knowledge to early-stage drug discovery – the GSK experience Vanderwall, Dana E.
2011
15-16 p. 646-653
8 p.
artikel
81 Molecular simulations of carbohydrates and protein–carbohydrate interactions: motivation, issues and prospects Fadda, Elisa
2010
15-16 p. 596-609
14 p.
artikel
82 Molecular understanding of curcumin in diabetic nephropathy Soetikno, Vivian
2013
15-16 p. 756-763
8 p.
artikel
83 mTOR as a multifunctional therapeutic target in HIV infection Nicoletti, Ferdinando
2011
15-16 p. 715-721
7 p.
artikel
84 Multipotent antioxidants: from screening to design Zhang, Hong-Yu
2006
15-16 p. 749-754
6 p.
artikel
85 Needed: system dynamics for the drug discovery process Sirois, Suzanne
2008
15-16 p. 708-715
8 p.
artikel
86 Network analysis has diverse roles in drug discovery Hasan, Samiul
2012
15-16 p. 869-874
6 p.
artikel
87 New Court guidance on repackaging of parallel traded products Wright, Elisabethann
2007
15-16 p. 591-593
3 p.
artikel
88 New tools for functional genomic analysis Chen, Xin
2009
15-16 p. 754-760
7 p.
artikel
89 New Zealand: unique biodiversity and world-class science converge Boalch, Chris
2006
15-16 p. 677-680
4 p.
artikel
90 Non-peptidyl insulin mimetics as a potential antidiabetic agent Nankar, Rakesh P.
2013
15-16 p. 748-755
8 p.
artikel
91 Orphan drug development across Europe: bottlenecks and opportunities Heemstra, Harald E.
2008
15-16 p. 670-676
7 p.
artikel
92 Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only Kell, Douglas B.
2011
15-16 p. 704-714
11 p.
artikel
93 Pharmacokinetics and the drug–target residence time concept Dahl, Göran
2013
15-16 p. 697-707
11 p.
artikel
94 Physiological, pathological and potential therapeutic roles of adipokines Falcão-Pires, Inês
2012
15-16 p. 880-889
10 p.
artikel
95 Potentiation strategies of dendritic cell-based antitumor vaccines: combinational therapy takes the front seat Torabi-Rahvar, Monireh
2011
15-16 p. 733-740
8 p.
artikel
96 Preclinical assessment of cardiac toxicity Kettenhofen, Ralf
2008
15-16 p. 702-707
6 p.
artikel
97 Progress and problems in the exploration of therapeutic targets 2006
15-16 p. 717-
1 p.
artikel
98 Progressing preclinical drug candidates: strategies on preclinical safety studies and the quest for adequate exposure Higgins, John
2012
15-16 p. 828-836
9 p.
artikel
99 Progress in the development of peroxide-based anti-parasitic agents Muraleedharan, K.M.
2009
15-16 p. 793-803
11 p.
artikel
100 Pyrimidin-4-yl phenols as anti-infective agents Edwards, Paul
2006
15-16 p. 768-769
2 p.
artikel
101 R&D investments for neglected diseases can be sensitive to the economic goal of pharmaceutical companies Dimitri, Nicola
2012
15-16 p. 818-823
6 p.
artikel
102 Recent advances in glucokinase activators for the treatment of type 2 diabetes Pal, Manojit
2009
15-16 p. 784-792
9 p.
artikel
103 Recent PDE4 inhibitor clinical candidates Yeung, Kap-Sun
2009
15-16 p. 812-813
2 p.
artikel
104 Relaxin family peptide receptors – from orphans to therapeutic targets van der Westhuizen, Emma T.
2008
15-16 p. 640-651
12 p.
artikel
105 Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases Dong, Ming
2010
15-16 p. 622-629
8 p.
artikel
106 ROCK: the Roche medicinal chemistry knowledge application – design, use and impact Mayweg, Alexander
2011
15-16 p. 691-696
6 p.
artikel
107 Screening the receptorome: an efficient approach for drug discovery and target validation Strachan, Ryan T.
2006
15-16 p. 708-716
9 p.
artikel
108 Seeding drug discovery: integrating telomerase cancer biology and cellular senescence to uncover new therapeutic opportunities in targeting cancer stem cells Keith, W Nicol
2007
15-16 p. 611-621
11 p.
artikel
109 Strategic alliances and market risk Havenaar, Matthias
2012
15-16 p. 824-827
4 p.
artikel
110 Strategic groups in the biopharmaceutical industry: implications for performance Erden, Zeynep
2009
15-16 p. 726-730
5 p.
artikel
111 Strategies to support drug discovery through integration of systems and data Waller, Chris L.
2007
15-16 p. 634-639
6 p.
artikel
112 Synthetic library design Huwe, Christoph M.
2006
15-16 p. 763-767
5 p.
artikel
113 Systematic characterization of structure–activity relationships and ADMET compliance: a case study Yongye, Austin B.
2013
15-16 p. 732-739
8 p.
artikel
114 Targeting atypical trypanosomatid DNA topoisomerase I Balaña-Fouce, Rafael
2006
15-16 p. 733-740
8 p.
artikel
115 Targeting mTOR as a novel therapeutic strategy for traumatic CNS injuries Arachchige Don, Aruni S.
2012
15-16 p. 861-868
8 p.
artikel
116 The challenges of product development and commercialization in a convergence technology world: focus on regenerative medicine Tozer, Dean
2010
15-16 p. 587-589
3 p.
artikel
117 The Drug Discovery Portal: a resource to enhance drug discovery from academia Clark, Rachel L.
2010
15-16 p. 679-683
5 p.
artikel
118 The future is here: tumour profiling in day-to-day clinical practice Lemech, Charlotte R.
2013
15-16 p. 689-691
3 p.
artikel
119 The impact of interferon-β treatment on the blood–brain barrier Kraus, Jörg
2006
15-16 p. 755-762
8 p.
artikel
120 Therapeutic strategies for the treatment of stroke Green, A. Richard
2006
15-16 p. 681-693
13 p.
artikel
121 The solution-phase design and synthesis of libraries for the discovery of CNS active substances Edwards, Paul John
2011
15-16 p. 742-744
3 p.
artikel
122 The Tox21 robotic platform for the assessment of environmental chemicals – from vision to reality Attene-Ramos, Matias S.
2013
15-16 p. 716-723
8 p.
artikel
123 The value of proteasome inhibition in cancer Cvek, Boris
2008
15-16 p. 716-722
7 p.
artikel
124 Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward? Patwardhan, Bhushan
2009
15-16 p. 804-811
8 p.
artikel
125 Translation of drug effects from experimental models of neuropathic pain and analgesia to humans Taneja, Amit
2012
15-16 p. 837-849
13 p.
artikel
126 What made sesquiterpene lactones reach cancer clinical trials? Ghantous, Akram
2010
15-16 p. 668-678
11 p.
artikel
                             126 gevonden resultaten
 
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