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                             90 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Activity profile relationships between structurally similar promiscuous compounds Hu, Ye
2013
69 C p. 393-398
6 p.
artikel
2 Aggrecanase-2 inhibitors based on the acylthiosemicarbazide zinc-binding group Maingot, Lucie
2013
69 C p. 244-261
18 p.
artikel
3 A novel [1,2,4] triazolo [1,5-a] pyrimidine-based phenyl-linked steroid dimer: Synthesis and its cytotoxic activity Yu, Bin
2013
69 C p. 323-330
8 p.
artikel
4 Anticancer evaluation of some newly synthesized N-nicotinonitrile derivative Shamroukh, Ahmed H.
2013
69 C p. 521-526
6 p.
artikel
5 Biological activity of neutral and cationic iridium(III) complexes with κP and κP,κS coordinated Ph2PCH2S(O) x Ph (x = 0–2) ligands Ludwig, Gerd
2013
69 C p. 216-222
7 p.
artikel
6 3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage Park, So-Eun
2013
69 C p. 139-145
7 p.
artikel
7 Carbonic anhydrase inhibitors. Synthesis of heterocyclic 4-substituted pyridine-3-sulfonamide derivatives and their inhibition of the human cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII Sławiński, Jarosław
2013
69 C p. 701-710
10 p.
artikel
8 cis-Dichloroplatinum(II) complexes tethered to dibenzo[c,h][1,6]naphthyridin-6-ones: Synthesis and cytotoxicity in human cancer cell lines in vitro Desbois, Nicolas
2013
69 C p. 719-727
9 p.
artikel
9 Design and application of a rigid quinazolone scaffold based on two-face Bim α-helix mimicking Zhang, Zhichao
2013
69 C p. 711-718
8 p.
artikel
10 Design, syntheses, and characterization of pharmacophore based chemokine receptor CCR5 antagonists as anti prostate cancer agents Arnatt, Christopher K.
2013
69 C p. 647-658
12 p.
artikel
11 Design, synthesis and biological activities of some 7-aminocephalosporanic acid derivatives Basoglu, Serap
2013
69 C p. 622-631
10 p.
artikel
12 Design, synthesis and biological evaluation of a novel class of potent TGR5 agonists based on a 4-phenyl pyridine scaffold Zhu, Junjie
2013
69 C p. 55-68
14 p.
artikel
13 Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy Chen, Yue-Ting
2013
69 C p. 399-412
14 p.
artikel
14 Design, synthesis and biological evaluation of 2-substituted quinolines as potential antileishmanial agents Gopinath, Vadiraj S.
2013
69 C p. 527-536
10 p.
artikel
15 Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents Elicio, Pablo D.
2013
69 C p. 480-489
10 p.
artikel
16 Design, synthesis and efficacy of novel G protein-coupled receptor kinase 2 inhibitors Carotenuto, Alfonso
2013
69 C p. 384-392
9 p.
artikel
17 Design, synthesis, and in vitro cancer cell growth inhibition evaluation and antimalarial testing of trioxanes installed in cyclic 2-enoate substructures Hossain, Md. Imran
2013
69 C p. 294-309
16 p.
artikel
18 Design, synthesis and structure–activity relationship of novel quinoxaline derivatives as cancer chemopreventive agent by inhibition of tyrosine kinase receptor Galal, Shadia A.
2013
69 C p. 115-124
10 p.
artikel
19 Design, synthesis, and structure–activity relationships of novel 6,7-disubstituted-4-phenoxyquinoline derivatives as potential antitumor agents Tang, Qidong
2013
69 C p. 77-89
13 p.
artikel
20 Development of 3,4-dihydroisoquinolin-1(2H)-one derivatives for the Positron Emission Tomography (PET) imaging of σ2 receptors Abate, Carmen
2013
69 C p. 920-930
11 p.
artikel
21 Development of 3-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel Mycobacterium tuberculosis pantothenate synthetase inhibitors Samala, Ganesh
2013
69 C p. 356-364
9 p.
artikel
22 Discovery of 4-amino-2-(thio)phenol derivatives as novel protein kinase and angiogenesis inhibitors for the treatment of cancer: Synthesis and biological evaluation. Part II Xu, Fuming
2013
69 C p. 191-200
10 p.
artikel
23 Discovery of a potent dual EGFR/HER-2 inhibitor L-2 (selatinib) for the treatment of cancer Zhang, Long
2013
69 C p. 833-841
9 p.
artikel
24 Editorial board 2013
69 C p. IFC-
1 p.
artikel
25 Experimental and molecular modeling studies on the interaction of the Ru(II)-piroxicam with DNA and BSA Jannesari, Zahra
2013
69 C p. 577-590
14 p.
artikel
26 Flavones as isosteres of 4(1H)-quinolones: Discovery of ligand efficient and dual stage antimalarial lead compounds Rodrigues, Tiago
2013
69 C p. 872-880
9 p.
artikel
27 Graphical contents list 2013
69 C p. iii-xxv
nvt p.
artikel
28 2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymerase Küçükgüzel, İlkay
2013
69 C p. 931-941
11 p.
artikel
29 2-(2-Hydrazinyl)thiazole derivatives: Design, synthesis and in vitro antimycobacterial studies Makam, Parameshwar
2013
69 C p. 564-576
13 p.
artikel
30 Identification and characterization of novel indole based small molecules as anticancer agents through SIRT1 inhibition Panathur, Naveen
2013
69 C p. 125-138
14 p.
artikel
31 Indenoindoles and cyclopentacarbazoles as bioactive compounds: Synthesis and biological applications Rongved, Pal
2013
69 C p. 465-479
15 p.
artikel
32 In vitro antimalarial activity, β-haematin inhibition and structure–activity relationships in a series of quinoline triazoles Joshi, Mukesh C.
2013
69 C p. 338-347
10 p.
artikel
33 β-Ionone derived chalcones as potent antiproliferative agents Sharma, Vishal
2013
69 C p. 310-315
6 p.
artikel
34 Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists Ostacolo, Carmine
2013
69 C p. 659-669
11 p.
artikel
35 Mastering tricyclic ring systems for desirable functional cannabinoid activity Petrov, Ravil R.
2013
69 C p. 881-907
27 p.
artikel
36 Microwave assisted synthesis of dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones; synthesis, in vitro antimicrobial and anticancer activities of novel coumarin substituted dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones Puttaraju, Kallimeledoddi B.
2013
69 C p. 316-322
7 p.
artikel
37 Modulation of A2B adenosine receptor by 1-Benzyl-3-ketoindole derivatives Taliani, Sabrina
2013
69 C p. 331-337
7 p.
artikel
38 Monoamine oxidase inhibitory activity of 3,5-biaryl-4,5-dihydro-1H-pyrazole-1-carboxylate derivatives Vishnu Nayak, B.
2013
69 C p. 762-767
6 p.
artikel
39 Multifunctional tacrine–flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease Li, Su-Yi
2013
69 C p. 632-646
15 p.
artikel
40 New combination of pharmacophoric elements of potent σ 1 ligands: Design, synthesis and σ receptor affinity of aminoethyl substituted tetrahydrobenzothiophenes Harel, Dipak
2013
69 C p. 490-497
8 p.
artikel
41 New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: Synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death Queiroz, Maria-João R.P.
2013
69 C p. 855-862
8 p.
artikel
42 New orally effective 3-(2-nitro)phenylpropanamide analgesic derivatives: Synthesis and antinociceptive evaluation Since, Marc
2013
69 C p. 728-734
7 p.
artikel
43 New synthetic aliphatic sulfonamido-quaternary ammonium salts as anticancer chemotherapeutic agents Song, Doona
2013
69 C p. 670-677
8 p.
artikel
44 Nonpeptidic angiotensin II AT1 receptor antagonists derived from 6-substituted aminocarbonyl and acylamino benzimidazoles Zhang, Jun
2013
69 C p. 44-54
11 p.
artikel
45 Novel acetamidothiazole derivatives: Synthesis and in vitro anticancer evaluation Ali, Ahmed R.
2013
69 C p. 908-919
12 p.
artikel
46 Novel 6β-acylaminomorphinans with analgesic activity Váradi, András
2013
69 C p. 786-789
4 p.
artikel
47 Novel heterocyclic-fused pyrimidine derivatives: Synthesis, molecular modeling and pharmacological screening Arafa, Reem K.
2013
69 C p. 498-507
10 p.
artikel
48 Novel N-methylsulfonamide and retro-N-methylsulfonamide derivatives as 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) inhibitors with good ADME-related physicochemical parameters Perspicace, Enrico
2013
69 C p. 201-215
15 p.
artikel
49 Novel nonsecosteroidal VDR agonists with phenyl-pyrrolyl pentane skeleton Shen, Wei
2013
69 C p. 768-778
11 p.
artikel
50 Novel N-4-piperazinyl-ciprofloxacin-chalcone hybrids: Synthesis, physicochemical properties, anticancer and topoisomerase I and II inhibitory activity Abdel-Aziz, Mohamed
2013
69 C p. 427-438
12 p.
artikel
51 Novel promising linezolid analogues: Rational design, synthesis and biological evaluation De Rosa, Margherita
2013
69 C p. 779-785
7 p.
artikel
52 PAMAM dendrimer derivatives as a potential drug for antithrombotic therapy Durán-Lara, Esteban
2013
69 C p. 601-608
8 p.
artikel
53 Platinum(II) complexes with N-monoalkyl 1R,2R-diaminocyclohexane derivatives as carrier ligands and 3-hydroxycyclobutane-1,1-dicarboxylate as a leaving group: Potent cytotoxicity and DNA binding ability Fang, Lei
2013
69 C p. 842-847
6 p.
artikel
54 Preparation and biological evaluation of 99mTc-N4IPA for single photon emission computerized tomography imaging of hypoxia in mouse tumor Li, Nan
2013
69 C p. 223-231
9 p.
artikel
55 Pyranoxanthones: Synthesis, growth inhibitory activity on human tumor cell lines and determination of their lipophilicity in two membrane models Azevedo, Carlos M.G.
2013
69 C p. 798-816
19 p.
artikel
56 Pyrazole containing natural products: Synthetic preview and biological significance Kumar, Vinod
2013
69 C p. 735-753
19 p.
artikel
57 QSAR modeling of aromatase inhibitory activity of 1-substituted 1,2,3-triazole analogs of letrozole Nantasenamat, Chanin
2013
69 C p. 99-114
16 p.
artikel
58 Squaric acid/4-aminoquinoline conjugates: Novel potent antiplasmodial agents Ribeiro, Carlos J.A.
2013
69 C p. 365-372
8 p.
artikel
59 Structure-based design, synthesis and biological evaluation of novel anthra[1,2-d]imidazole-6,11-dione homologues as potential antitumor agents Chen, Tsung-Chih
2013
69 C p. 278-293
16 p.
artikel
60 Synthesis and allosteric modulation of the dopamine receptor by peptide analogs of l-prolyl-l-leucyl-glycinamide (PLG) modified in the l-proline or l-proline and l-leucine scaffolds Ferreira da Costa, Joana
2013
69 C p. 146-158
13 p.
artikel
61 Synthesis and antibacterial activity of novel modified 5-O-mycaminose 14-membered ketolides Xu, Yanpeng
2013
69 C p. 174-181
8 p.
artikel
62 Synthesis and anticancer activity of some novel 2-phenazinamine derivatives Gao, Xiaochun
2013
69 C p. 1-9
9 p.
artikel
63 Synthesis and anticancer activity of some novel trifluoromethylquinolines carrying a biologically active benzenesulfonamide moiety Al-Dosari, Mohammed S.
2013
69 C p. 373-383
11 p.
artikel
64 Synthesis and antiproliferative activity of benzofuran-based analogs of cercosporamide against non-small cell lung cancer cell lines Bazin, Marc-Antoine
2013
69 C p. 823-832
10 p.
artikel
65 Synthesis and antitumor activities of novel thiourea α-aminophosphonates from dehydroabietic acid Huang, Xiao-Chao
2013
69 C p. 508-520
13 p.
artikel
66 Synthesis and antiviral activity of a novel class of (5-oxazolyl)phenyl amines Zhong, Zhao-Jin
2013
69 C p. 32-43
12 p.
artikel
67 Synthesis and biological activity of mycophenolic acid-amino acid derivatives Iwaszkiewicz-Grzes, Dorota
2013
69 C p. 863-871
9 p.
artikel
68 Synthesis and biological evaluation of novel delta (δ) opioid receptor ligands with diazatricyclodecane skeletons Loriga, Giovanni
2013
69 C p. 413-426
14 p.
artikel
69 Synthesis and biological evaluation of phenyl substituted polyoxygenated xanthone derivatives as anti-hepatoma agents Dai, Ming
2013
69 C p. 159-166
8 p.
artikel
70 Synthesis and cytotoxic activity of some novel steroidal C-17 pyrazolinyl derivatives Fan, Ning-Juan
2013
69 C p. 182-190
9 p.
artikel
71 Synthesis and evaluation of α-ketotriazoles and α,β-diketotriazoles as inhibitors of Mycobacterium tuberculosis Menendez, Christophe
2013
69 C p. 167-173
7 p.
artikel
72 Synthesis and evaluation of (Z)-2,3-diphenylacrylonitrile analogs as anti-cancer and anti-microbial agents Alam, Mohammad Sayed
2013
69 C p. 790-797
8 p.
artikel
73 Synthesis and in vitro and in vivo evaluation of antimalarial polyamines Liew, Lydia P.P.
2013
69 C p. 22-31
10 p.
artikel
74 Synthesis and in vitro/in vivo antibacterial activity of oxazolidinones having thiocarbamate at C-5 on the A-ring and an amide- or urea-substituted [1,2,5]triazepane or [1,2,5]oxadiazepane as the C-ring Suzuki, Hideyuki
2013
69 C p. 262-277
16 p.
artikel
75 Synthesis and SAR study of novel 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as potent eIF2·GTP·Met-tRNAi Met ternary complex inhibitors Denoyelle, Séverine
2013
69 C p. 537-553
17 p.
artikel
76 Synthesis, antibacterial and antioxidant activities of new 1-alkyl-4-(1-alkyl-4-oxo-1,4-dihydroquinolin-2-yl)pyridinium bromides Kahriman, Nuran
2013
69 C p. 348-355
8 p.
artikel
77 Synthesis, antimicrobial, antioxidant activities of novel 6-aryl-5-cyano thiouracil derivatives Mohamed, M.S.
2013
69 C p. 591-600
10 p.
artikel
78 Synthesis, characterization, antiparasitic and cytotoxic evaluation of thioureas conjugated to polyamine scaffolds Stringer, Tameryn
2013
69 C p. 90-98
9 p.
artikel
79 Synthesis, cytotoxicity and DNA binding of oxoazabenzo[de]anthracenes derivatives in colon cancer Caco-2 cells Di Salvo, Alberto
2013
69 C p. 754-761
8 p.
artikel
80 Synthesis, hypoglycemic activity and molecular modeling studies of pyrazole-3-carbohydrazides designed by a CoMFA model Hernández-Vázquez, Eduardo
2013
69 C p. 10-21
12 p.
artikel
81 Synthesis of conformationally constrained γ-d-glutamyl-meso-diaminopimelic acid derivatives as ligands of nucleotide-binding oligomerization domain protein 1 (Nod1) Jakopin, Žiga
2013
69 C p. 232-243
12 p.
artikel
82 Synthesis of lipoic acid–peptide conjugates and their effect on collagen and melanogenesis Lu, Chichong
2013
69 C p. 449-454
6 p.
artikel
83 Synthesis of new andrographolide derivatives and evaluation of their antidyslipidemic, LDL-oxidation and antioxidant activity Pandeti, Sukanya
2013
69 C p. 439-448
10 p.
artikel
84 Synthesis of novel benzo[4,5]thiazolo[1,2-a]pyrimidine-3-carboxylate derivatives and biological evaluation as potential anticancer agents Nagarapu, Lingaiah
2013
69 C p. 817-822
6 p.
artikel
85 Synthesis of pyrido[2,1-a]isoquinolin-4-ones and oxazino[2,3-a]isoquinolin-4-ones: New inhibitors of mitochondrial respiratory chain Moreno, Laura
2013
69 C p. 69-76
8 p.
artikel
86 Synthesis of quinoidal molecules: Strategies towards bioactive compounds with an emphasis on lapachones de Castro, Solange L.
2013
69 C p. 678-700
23 p.
artikel
87 Synthesis, physicochemical properties of allopurinol derivatives and their biological activity against Trypanosoma cruzi Raviolo, M.A.
2013
69 C p. 455-464
10 p.
artikel
88 The antitumor activity of zinc(II) and copper(II) complexes with 5,7-dihalo-substituted-8-quinolinoline Liu, Yan-Cheng
2013
69 C p. 554-563
10 p.
artikel
89 The development of bis(hydroxymethyl)pyrrole analogs as bifunctional DNA cross-linking agents and their chemotherapeutic potential Su, Tsann-Long
2013
69 C p. 609-621
13 p.
artikel
90 Thermoresponsive dendrimers based on oligoethylene glycols: Design, synthesis and cytotoxic activity against MCF-7 breast cancer cells Abdel-Rahman, Mona A.
2013
69 C p. 848-854
7 p.
artikel
                             90 gevonden resultaten
 
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