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                             35 results found
no title author magazine year volume issue page(s) type
1 Comparative analysis of the dual EGFR-DNA targeting and growth inhibitory properties of 6-mono-alkylamino- and 6,6-dialkylaminoquinazoline-based type II combi-molecules Schmitt, Julie

192 C p.
article
2 Crystal structure of O-Acetylserine sulfhydralase (OASS) isoform 3 from Entamoeba histolytica: Pharmacophore-based virtual screening and validation of novel inhibitors Dharavath, Sudhaker

192 C p.
article
3 Cyclometalated Ir(III)-8-oxychinolin complexes acting as red-colored probes for specific mitochondrial imaging and anticancer drugs Meng, Ting

192 C p.
article
4 Design and synthesis of selective degraders of EGFRL858R/T790M mutant Zhang, Xin

192 C p.
article
5 Design and synthesis of tripeptidyl furylketones as selective inhibitors against the β5 subunit of human 20S proteasome Sun, Qi

192 C p.
article
6 Design, synthesis and biological evaluation of novel indazole-based derivatives as potent HDAC inhibitors via fragment-based virtual screening Liu, Jian

192 C p.
article
7 Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy)acetamide-based antituberculosis agents Borsoi, Ana Flávia

192 C p.
article
8 Design, synthesis, and evaluation of N-phenyl-4-(2-phenylsulfonamido)-benzamides as microtubule-targeting agents in drug-resistant cancer cells, displaying HDAC inhibitory response Wu, Wei-Cheng

192 C p.
article
9 Development of bivalent triarylalkene- and cyclofenil-derived dual estrogen receptor antagonists and downregulators Knox, Alexandra

192 C p.
article
10 Diarylpentanoids with antitumor activity: A critical review of structure-activity relationship studies Moreira, Joana

192 C p.
article
11 Discovery of a promising agent IQZ23 for the treatment of obesity and related metabolic disorders Rao, Yong

192 C p.
article
12 Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate Chen, Tao

192 C p.
article
13 Discovery of novel tertiary amide derivatives as NEDDylation pathway activators to inhibit the tumor progression in vitro and in vivo Fu, Dong-Jun

192 C p.
article
14 Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity Zhang, Xuan

192 C p.
article
15 Discovery of pyrazole derivatives as cellular active inhibitors of histone lysine specific demethylase 5B (KDM5B/JARID1B) Zhao, Bing

192 C p.
article
16 Discovery of pyridine tetrahydroisoquinoline thiohydantoin derivatives with low blood-brain barrier penetration as the androgen receptor antagonists Xu, Xi

192 C p.
article
17 Editorial Board
192 C p.
article
18 Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors Řehulka, Jiří

192 C p.
article
19 Graphical abstract TOC
192 C p.
article
20 Graphical abstract TOC
192 C p.
article
21 Graphical abstract TOC continued
192 C p.
article
22 Histone deacetylase 3 (HDAC3) inhibitors as anticancer agents: A review Sarkar, Rajat

192 C p.
article
23 Janus kinases (JAKs): The efficient therapeutic targets for autoimmune diseases and myeloproliferative disorders Xu, Pengfei

192 C p.
article
24 Multi-target drug discovery: An opportunity for novel and repurposed bioactive compounds Alcaro, Stefano

192 C p.
article
25 Non-polyphenolic natural inhibitors of amyloid aggregation Ma, Liang

192 C p.
article
26 Novel androgen receptor antagonist identified by structure-based virtual screening, structural optimization, and biological evaluation Tang, Qin

192 C p.
article
27 Overview of cannabidiol (CBD) and its analogues: Structures, biological activities, and neuroprotective mechanisms in epilepsy and Alzheimer’s disease Li, Han

192 C p.
article
28 Repurposed drug candidates for antituberculosis therapy An, Qi

192 C p.
article
29 Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery Yang, Ling-Ling

192 C p.
article
30 Structure-thermodynamics-relationships of hepatitis C viral NS3 protease inhibitors Wypych, Rachel M.

192 C p.
article
31 Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer’s disease Tseng, Hui-Ju

192 C p.
article
32 Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6 Méndez, Diego

192 C p.
article
33 Synthesis of multimeric pyrrolidine iminosugar inhibitors of human β-glucocerebrosidase and α-galactosidase A: First example of a multivalent enzyme activity enhancer for Fabry disease Martínez-Bailén, Macarena

192 C p.
article
34 The development of advanced structural framework as multi-target-directed ligands for the treatment of Alzheimer’s disease Sang, Zhipei

192 C p.
article
35 True or false? Challenges and recent highlights in the development of aspirin prodrugs Willetts, Steffan

192 C p.
article
                             35 results found
 
 Koninklijke Bibliotheek - National Library of the Netherlands