nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism 1 1 Abbreviations: MTs, microtubules; MAPs, microtubule-associated proteins; MAP4, microtubule-associated protein-4; PTX, paclitaxel; EPOA, epothilone A; EPOB, epothilone B; EPOA-R, epothilone A-resistant; COL, colchicine; VCR, vincristine; and VBL, vinblastine.
|
Poruchynsky, Marianne S. |
|
2001 |
62 |
11 |
p. 1469-1480 12 p. |
artikel |
2 |
Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy? 1 1 Abbreviations: NSAIDs, nonsteroidal anti-inflammatory drugs; COX, cyclooxygenase; LT, leukotriene; 5-LOX, 5-lipoxygenase; PG, prostaglandin; DFU, 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsuphonyl)-phenyl-2(5H)-furanone; and DFP, diisopropyl fluorophosphate.
|
Fiorucci, Stefano |
|
2001 |
62 |
11 |
p. 1433-1438 6 p. |
artikel |
3 |
Effect of atorvastatin, simvastatin, and lovastatin on the metabolism of cholesterol and triacylglycerides in HepG2 cells
|
Scharnagl, Hubert |
|
2001 |
62 |
11 |
p. 1545-1555 11 p. |
artikel |
4 |
Effects of nitric oxide and hydrogen peroxide on histamine release from RBL-2H3 cells 1 1 Abbreviations: ATP, adenosine 5′-triphosphate;BSA, bovine serum albumin;Con A, concanavalin A; DAG, diacylglycerol; DiC8, 1,2-dioctanoyl-sn-glycerol; DMSO, dimethyl sulphoxide; DNP-HSA, dinitrophenol-human serum albumin conjugate; FCS, fetal calf serum; H2O2, hydrogen peroxide; HR, histamine release; IP3, inositol-1,4,5-triphosphate; L-NA, Nω-nitro-l-arginine; L-NAME, Nω-nitro-l-arginine- methyl ester; LPS, lipopolysaccharide; MB, methylene blue; MC, mast cell; MEM, minimal essential medium; NaF, sodium fluoride; NaNO3, sodium nitrate; NO, nitric oxide; PBS, phosphate buffered saline; PKC, protein kinase C; PLC, phospholipase C; ROS, reactive oxygen species; RPMC, rat peritoneal mast cells; and SNP, sodium nitroprusside
|
Wan, Beatrice Y.C. |
|
2001 |
62 |
11 |
p. 1537-1544 8 p. |
artikel |
5 |
Enhancing effect of zinc on astroglial and cerebral endothelial histamine uptake 1 1 Abbreviations: HA, histamine; FCS, fetal calf serum; MEM, minimal essential medium; and NEM, N-ethylmaleimide.
|
Huszti, Zsuzsanna |
|
2001 |
62 |
11 |
p. 1491-1500 10 p. |
artikel |
6 |
Expression of rat aldehyde reductase AKR7A1: influence of age and sex and tissue-specific inducibility☆ 1 ☆ This work was funded partly by a grant from the Association for International Cancer Research. EME was supported by a Beit Memorial Fellowship and VPK was supported by a Biomedical Research Centre Studentship. The experiments performed in Stockholm were supported by the Knut and Alice Wallenberg Foundation. 1 Abbreviations: 2-CBA, 2-carboxybenzaldehyde; 4-NBA, 4-nitrobenzaldehyde; 9,10-PQ, 9,10-phenanthrenequinone; NQO1, NAD(P)H:quinone oxidoreductase; GH, growth hormone; GSH, glutathione; and SDS, sodium dodecyl sulfate.
|
Grant, Anne |
|
2001 |
62 |
11 |
p. 1511-1519 9 p. |
artikel |
7 |
Induction of G2/M phase arrest and apoptosis by a new synthetic anti-cancer agent, DW2282, in promyelocytic leukemia (HL-60) cells 1 1 Abbreviations: FBS, fetal bovine serum; PARP, poly(ADP-ribose) polymerase; and MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide.
|
Piao, Wenhua |
|
2001 |
62 |
11 |
p. 1439-1447 9 p. |
artikel |
8 |
Inhibitory properties of the anti-bothropic complex from Didelphis albiventris serum on toxic and pharmacological actions of metalloproteases and myotoxins from bothrops asper venom 1 1 Abbreviations: SVMPs, snake venom metalloproteases; ABC, anti-bothropic complex from Didelphis albiventris serum; DA43, 43-kDa subunit of anti-bothropic complex from D. albiventris serum; DA45, 45-kDa subunit of anti-bothropic complex from D. albiventris serum; MHD, dose able to induce a hemorrhagic lesion of 10 mm diameter; BaP1, basic hemorrhagic metalloprotease from Bothrops asper venom; BaH4, acidic hemorrhagic metalloprotease from B. asper venom; Basp-I, myotoxin I from B. asper venom; Basp-II, myotoxin II from B. asper venom; and Basp-III, myotoxin III from B. asper venom.
|
Trento, Edilson P. |
|
2001 |
62 |
11 |
p. 1521-1529 9 p. |
artikel |
9 |
Positive modulation by Ras of interleukin-1β-mediated nitric oxide generation in insulin-secreting clonal β (HIT-T15) cells 1 1 Abbreviations: IL-1β interleukin-1β; NO, nitric oxide; iNOS, induced nitric oxide synthase; IDDM, insulin-dependent diabetes mellitus; LT, lethal toxin; CNF1, cytotoxic necrotizing factor 1; PTMs, post-translational modifications; and L-NMMA: N-monomethyl-l-arginine monoacetate.
|
Tannous, Marie |
|
2001 |
62 |
11 |
p. 1459-1468 10 p. |
artikel |
10 |
Reduction in serotonin synthesis following acute and chronic treatments with paroxetine, a selective serotonin reuptake inhibitor, in rat brain: an autoradiographic study with α-[14C]methyl-l-tryptophan 2 2 Abbreviations: 5-HT, serotonin, 5-hydroxytryptamine; α-[14C]MTrp, α-[14C]methyl-l-tryptophan; SSRI, selective serotonin reuptake inhibitor; and α-[14C]M5HT, α-[14C]methyl-5-HT.
|
Yamane, Fumitaka |
|
2001 |
62 |
11 |
p. 1481-1489 9 p. |
artikel |
11 |
Retinoid X receptor agonist elevation of serum triglycerides in rats by potentiation of retinoic acid receptor agonist induction or by action as single agents 2 2 Abbreviations: RARs, retinoic acid receptors; and RXRs, retinoid X receptors.
|
Standeven, Andrew M. |
|
2001 |
62 |
11 |
p. 1501-1509 9 p. |
artikel |
12 |
Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated CYP1A1 and CYP1B1 induction by 12-O-tetradecanoylphorbol-13-acetate: role of transforming growth factor β and mitogen-activated protein kinases 1 1 Abbreviations: AHR, aryl hydrocarbon receptor; ALDH4, aldehyde dehydrogenase class 4; ARNT, aryl hydrocarbon receptor nuclear translocator; CYP, cytochrome P450; DRE, dioxin response element; ERKs, extracellular signal-regulated kinases; MAPK, mitogen-activated protein kinase; MEK, MAPK kinase; NQO1, NADP(H):quinone oxidoreductase; PKC, protein kinase C; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; TGFβ, transforming growth factor β; and TPA, 12-O-tetradecanoylphorbol-13-acetate.
|
Guo, Meng |
|
2001 |
62 |
11 |
p. 1449-1457 9 p. |
artikel |
13 |
Synthesis and pharmacological activity of a novel water-soluble hepatocyte-specific polymeric prodrug of prostaglandin E1 using lactosylated poly(l-glutamic hydrazide) as a carrier 1 1 Abbreviations: PGE1, prostaglandin E1; PLGA-HZ, poly(l-glutamic hydrazide); Lac-NH-PLGA, lactosylated poly(l-glutamic hydrazide); PGE1 conjugate, prostaglandin E1 prodrug using Lac-NH-PLGA as a carrier; DTPA anhydride, diethylenetriamine-N,N,N′,N″,N″-pentaacetic dianhydride; GPT, glutamic pyruvic transaminase; AUC, area under the plasma concentration-time curve; ROS, reactive oxygen species; and EP receptor, receptor for prostaglandins expressed on a plasma membrane.
|
Akamatsu, Ken |
|
2001 |
62 |
11 |
p. 1531-1536 6 p. |
artikel |
|