| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Acetylene containing cyclo(L-Tyr-L-Tyr)-analogs as mechanism-based inhibitors of CYP121A1 from Mycobacterium tuberculosis
|
Ortega Ugalde, Sandra
|
|
|
177 |
C |
p.
|
artikel
|
| 2 |
Adenosine A2B receptors inhibit K+ currents and cell differentiation in cultured oligodendrocyte precursor cells and modulate sphingosine-1-phosphate signaling pathway
|
Coppi, Elisabetta
|
|
|
177 |
C |
p.
|
artikel
|
| 3 |
β1-adrenoceptor-stimulated lactate production in cultured astrocytes is predominantly glycogen-independent
|
Jiang, Xianguo
|
|
|
177 |
C |
p.
|
artikel
|
| 4 |
Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment
|
Stark, Tibor
|
|
|
177 |
C |
p.
|
artikel
|
| 5 |
Alzheimer’s disease beyond amyloid: Can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery?
|
Mullane, Kevin
|
|
|
177 |
C |
p.
|
artikel
|
| 6 |
Apocynin prevents GM-CSF-induced-ERK1/2 activation and -neutrophil survival independently of its inhibitory effect on the phagocyte NADPH oxidase NOX2
|
Pintard, Coralie
|
|
|
177 |
C |
p.
|
artikel
|
| 7 |
Assessment of biased agonism at the A3 adenosine receptor using β-arrestin and miniGαi recruitment assays
|
Pottie, Eline
|
|
|
177 |
C |
p.
|
artikel
|
| 8 |
Assessment of structure-activity relationships and biased agonism at the Mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform
|
Vasudevan, Lakshmi
|
|
|
177 |
C |
p.
|
artikel
|
| 9 |
Atractylenolide II prevents radiation damage via MAPKp38/Nrf2 signaling pathway
|
Xiao, Changyan
|
|
|
177 |
C |
p.
|
artikel
|
| 10 |
Bitter taste receptors profiling in the human blood-cerebrospinal fluid-barrier
|
Duarte, Ana C.
|
|
|
177 |
C |
p.
|
artikel
|
| 11 |
Blocking STAT3 by pyrvinium pamoate causes metabolic lethality in KRAS-mutant lung cancer
|
Feng, JuanJuan
|
|
|
177 |
C |
p.
|
artikel
|
| 12 |
3-Bromopyruvate regulates the status of glycolysis and BCNU sensitivity in human hepatocellular carcinoma cells
|
Sun, Xiaodong
|
|
|
177 |
C |
p.
|
artikel
|
| 13 |
Consistent gastric pH-dependent effects of suppressors of gastric acid secretion on the antihypertensive responses to oral nitrite
|
Sanches-Lopes, Jessica M.
|
|
|
177 |
C |
p.
|
artikel
|
| 14 |
Corrigendum to “Crocin, a carotenoid, suppresses spindle microtubule dynamics and activates the mitotic checkpoint by binding to tubulin” [Biochem. Pharmacol. 163 (2019) 32–45]
|
Sawant, Avishkar V.
|
|
|
177 |
C |
p.
|
artikel
|
| 15 |
Cytosolic and mitochondrial ROS production resulted in apoptosis induction in breast cancer cells treated with Crocin: The role of FOXO3a, PTEN and AKT signaling
|
Nasimian, Ahmad
|
|
|
177 |
C |
p.
|
artikel
|
| 16 |
Dapagliflozin exerts positive effects on beta cells, decreases glucagon and does not alter beta- to alpha-cell transdifferentiation in mouse models of diabetes and insulin resistance
|
Tanday, Neil
|
|
|
177 |
C |
p.
|
artikel
|
| 17 |
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling
|
Li, Heng
|
|
|
177 |
C |
p.
|
artikel
|
| 18 |
4-Deoxyphorbol inhibits HIV-1 infection in synergism with antiretroviral drugs and reactivates viral reservoirs through PKC/MEK activation synergizing with vorinostat
|
De la Torre-Tarazona, H.E.
|
|
|
177 |
C |
p.
|
artikel
|
| 19 |
Differential contribution of metabotropic glutamate receptor 5 common allosteric binding site residues to biased allosteric agonism
|
Sengmany, Kathy
|
|
|
177 |
C |
p.
|
artikel
|
| 20 |
Dipeptidyl peptidase-4 inhibition improves endothelial senescence by activating AMPK/SIRT1/Nrf2 signaling pathway
|
Chen, Zhihui
|
|
|
177 |
C |
p.
|
artikel
|
| 21 |
Drug repurposing in cardiovascular diseases: Opportunity or hopeless dream?
|
Gelosa, Paolo
|
|
|
177 |
C |
p.
|
artikel
|
| 22 |
Drug uptake-based chemoresistance in breast cancer treatment
|
Muley, Helena
|
|
|
177 |
C |
p.
|
artikel
|
| 23 |
Editorial Board
|
|
|
|
177 |
C |
p.
|
artikel
|
| 24 |
Ellipticine blocks synergistic effects of IL-17A and TNF-α in epithelial cells and alleviates severe acute pancreatitis-associated acute lung injury
|
Li, Xingli
|
|
|
177 |
C |
p.
|
artikel
|
| 25 |
Essential role of the C148–C227 disulphide bridge in the human 5-HT2A homodimeric receptor
|
Cimadevila, M.
|
|
|
177 |
C |
p.
|
artikel
|
| 26 |
Estrogen receptor-positive (ER+) breast cancer treatment: Are multi-target compounds the next promising approach?
|
Ferreira Almeida, Cristina
|
|
|
177 |
C |
p.
|
artikel
|
| 27 |
Ethyl-p-methoxycinnamate enhances oct4 expression and reinforces pluripotency through the NF-κB signaling pathway
|
Ai, Huihan
|
|
|
177 |
C |
p.
|
artikel
|
| 28 |
Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor
|
Cieslikiewicz-Bouet, Monika
|
|
|
177 |
C |
p.
|
artikel
|
| 29 |
Genetic variants of N-acetyltransferases 1 and 2 (NAT1 and NAT2) in cynomolgus and rhesus macaques
|
Uno, Yasuhiro
|
|
|
177 |
C |
p.
|
artikel
|
| 30 |
Hepatocellular carcinoma: Gene expression profiling and regulation of xenobiotic-metabolizing cytochromes P450
|
Nekvindova, Jana
|
|
|
177 |
C |
p.
|
artikel
|
| 31 |
HMF causes anaphylactic symptoms by acting as a H1 receptor agonist
|
He, Huaizhen
|
|
|
177 |
C |
p.
|
artikel
|
| 32 |
Identification and validation of a novel dual small-molecule TLR2/8 antagonist
|
Grabowski, Maria
|
|
|
177 |
C |
p.
|
artikel
|
| 33 |
Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1
|
Biagioli, Michele
|
|
|
177 |
C |
p.
|
artikel
|
| 34 |
Immunoproteasome inhibitor DPLG3 attenuates experimental colitis by restraining NF-κB activation
|
Moallemian, Rezvan
|
|
|
177 |
C |
p.
|
artikel
|
| 35 |
18-kDa translocator protein association complexes in the brain: From structure to function
|
Costa, Barbara
|
|
|
177 |
C |
p.
|
artikel
|
| 36 |
Lobaplatin induces pyroptosis through regulating cIAP1/2, Ripoptosome and ROS in nasopharyngeal carcinoma
|
Chen, Zide
|
|
|
177 |
C |
p.
|
artikel
|
| 37 |
Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway
|
Hunto, Stephanie Triseptya
|
|
|
177 |
C |
p.
|
artikel
|
| 38 |
L-tetrahydropalmatine attenuates cisplatin-induced nephrotoxicity via selective inhibition of organic cation transporter 2 without impairing its antitumor efficacy
|
Li, Cui
|
|
|
177 |
C |
p.
|
artikel
|
| 39 |
Luteolin inhibits melanoma growth in vitro and in vivo via regulating ECM and oncogenic pathways but not ROS
|
Schomberg, John
|
|
|
177 |
C |
p.
|
artikel
|
| 40 |
Maresin conjugates in tissue regeneration 1 prevents lipopolysaccharide-induced cardiac dysfunction through improvement of mitochondrial biogenesis and function
|
Yang, Yi
|
|
|
177 |
C |
p.
|
artikel
|
| 41 |
Metabolically stable diphenylamine derivatives suppress androgen receptor and BET protein in prostate cancer
|
Yu, Jiang
|
|
|
177 |
C |
p.
|
artikel
|
| 42 |
Metabolism and interactions of antileprosy drugs
|
George, Joseph
|
|
|
177 |
C |
p.
|
artikel
|
| 43 |
miR-211-5p alleviates focal cerebral ischemia-reperfusion injury in rats by down-regulating the expression of COX2
|
Peng, Zhe
|
|
|
177 |
C |
p.
|
artikel
|
| 44 |
Molecular basis defining the selectivity of substituted isoquinolinones for the melatonin MT2 receptor
|
Chan, King H.
|
|
|
177 |
C |
p.
|
artikel
|
| 45 |
Molecular mechanisms and systemic targeting of NRF2 dysregulation in cancer
|
Kang, Jong-Su
|
|
|
177 |
C |
p.
|
artikel
|
| 46 |
Molecular mechanisms of the rapid-acting and long-lasting antidepressant actions of (R)-ketamine
|
Hashimoto, Kenji
|
|
|
177 |
C |
p.
|
artikel
|
| 47 |
Mutations of α1F45 residue of GABAA receptor loop G reveal its involvement in agonist binding and channel opening/closing transitions
|
Brodzki, Marek
|
|
|
177 |
C |
p.
|
artikel
|
| 48 |
Natural product piperine alleviates experimental allergic encephalomyelitis in mice by targeting dihydroorotate dehydrogenase
|
Liu, Zehui
|
|
|
177 |
C |
p.
|
artikel
|
| 49 |
NEK7 mediated assembly and activation of NLRP3 inflammasome downstream of potassium efflux in ventilator-induced lung injury
|
Liu, Huan
|
|
|
177 |
C |
p.
|
artikel
|
| 50 |
PAK1 inhibitor IPA-3 mitigates metastatic prostate cancer-induced bone remodeling
|
Verma, Arti
|
|
|
177 |
C |
p.
|
artikel
|
| 51 |
PCC0208009, an indirect IDO1 inhibitor, alleviates neuropathic pain and co-morbidities by regulating synaptic plasticity of ACC and amygdala
|
Wang, Yu
|
|
|
177 |
C |
p.
|
artikel
|
| 52 |
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
|
Yuliantie, Elita
|
|
|
177 |
C |
p.
|
artikel
|
| 53 |
Photodynamic inactivation mediated by 5-aminolevulinic acid of bacteria in planktonic and biofilm forms
|
Bohm, Gabriela Cervini
|
|
|
177 |
C |
p.
|
artikel
|
| 54 |
Probe dependence and biased potentiation of metabotropic glutamate receptor 5 is mediated by differential ligand interactions in the common allosteric binding site
|
Hellyer, Shane D.
|
|
|
177 |
C |
p.
|
artikel
|
| 55 |
Procyanidin B2 gallate regulates TNF-α production from T cells through inhibiting glycolytic activity via mTOR-HIF-1 pathway
|
Endo, Katsunori
|
|
|
177 |
C |
p.
|
artikel
|
| 56 |
Progesterone: An enigmatic ligand for the mineralocorticoid receptor
|
Baker, Michael E.
|
|
|
177 |
C |
p.
|
artikel
|
| 57 |
Pyrvinium pamoate attenuates non-alcoholic steatohepatitis: Insight on hedgehog/Gli and Wnt/β-catenin signaling crosstalk
|
El-Derany, Marwa O.
|
|
|
177 |
C |
p.
|
artikel
|
| 58 |
Rapamycin restrains platelet procoagulant responses via FKBP-mediated protection of mitochondrial integrity
|
Śledź, Kamila M.
|
|
|
177 |
C |
p.
|
artikel
|
| 59 |
Rational development of a high-affinity secretin receptor antagonist
|
Dong, Maoqing
|
|
|
177 |
C |
p.
|
artikel
|
| 60 |
Repurposing of drugs approved for cardiovascular diseases: Opportunity or mirage?
|
Gelosa, Paolo
|
|
|
177 |
C |
p.
|
artikel
|
| 61 |
Ribociclib mitigates cisplatin-associated kidney injury through retinoblastoma-1 dependent mechanisms
|
Kim, Ji Young
|
|
|
177 |
C |
p.
|
artikel
|
| 62 |
Role of the TLR4-androgen receptor axis and genistein in taxol-resistant ovarian cancer cells
|
Huang, Shang-Lang
|
|
|
177 |
C |
p.
|
artikel
|
| 63 |
Small-molecule arone protects from neuroinflammation in LPS-activated microglia BV-2 cells by targeting histone-remodeling chaperone ASF1a
|
Zhang, Xiao-Wen
|
|
|
177 |
C |
p.
|
artikel
|
| 64 |
Soraphen A enhances macrophage cholesterol efflux via indirect LXR activation and ABCA1 upregulation
|
Wang, Dongdong
|
|
|
177 |
C |
p.
|
artikel
|
| 65 |
Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells
|
Ortiz, Rina
|
|
|
177 |
C |
p.
|
artikel
|
| 66 |
Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: Novel insights into its pro-proteostatic effect
|
Sbardella, Diego
|
|
|
177 |
C |
p.
|
artikel
|
| 67 |
Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A
|
Bouknight, Kayla D.
|
|
|
177 |
C |
p.
|
artikel
|
| 68 |
Structure-activity relationship of flavonoid bifunctional inhibitors against Zika virus infection
|
Zou, Min
|
|
|
177 |
C |
p.
|
artikel
|
| 69 |
Targeting putative components of the mitochondrial permeability transition pore for novel therapeutics
|
Winquist, Raymond J.
|
|
|
177 |
C |
p.
|
artikel
|
| 70 |
Tetrahydroxy stilbene glycoside alleviated inflammatory damage by mitophagy via AMPK related PINK1/Parkin signaling pathway
|
Gao, Yan
|
|
|
177 |
C |
p.
|
artikel
|
| 71 |
The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and ameliorates acute kidney injury by targeting RIPK1 and RIPK3 kinases
|
Qin, Xia
|
|
|
177 |
C |
p.
|
artikel
|
| 72 |
The bitter taste receptor TAS2R14 regulates resveratrol transport across the human blood-cerebrospinal fluid barrier
|
Duarte, Ana C.
|
|
|
177 |
C |
p.
|
artikel
|
| 73 |
The role of epigenetics in the development of obesity
|
Obri, Arnaud
|
|
|
177 |
C |
p.
|
artikel
|
| 74 |
The seafood Musculus senhousei shows anti-influenza A virus activity by targeting virion envelope lipids
|
Chen, Daiwei
|
|
|
177 |
C |
p.
|
artikel
|
| 75 |
The selective 5-HT2A receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH
|
Jensen, Anders A.
|
|
|
177 |
C |
p.
|
artikel
|
| 76 |
The super-cooling compound icilin stimulates c-Fos and Egr-1 expression and activity involving TRPM8 channel activation, Ca2+ ion influx and activation of the ternary complex factor Elk-1
|
Ulrich, Myriam
|
|
|
177 |
C |
p.
|
artikel
|
| 77 |
Toosendanin-induced apoptosis in colorectal cancer cells is associated with the κ-opioid receptor/β-catenin signaling axis
|
Wang, Huihui
|
|
|
177 |
C |
p.
|
artikel
|
| 78 |
Upregulation of PKR pathway mediates glucolipotoxicity induced diabetic cardiomyopathy in vivo in wistar rats and in vitro in cultured cardiomyocytes
|
Mangali, Sureshbabu
|
|
|
177 |
C |
p.
|
artikel
|
| 79 |
Valproic acid affects fatty acid and triglyceride metabolism in HepaRG cells exposed to fatty acids by different mechanisms
|
Grünig, David
|
|
|
177 |
C |
p.
|
artikel
|
| 80 |
Virotherapy: From single agents to combinatorial treatments
|
Malfitano, Anna Maria
|
|
|
177 |
C |
p.
|
artikel
|
| 81 |
Vitamin D attenuates lung injury via stimulating epithelial repair, reducing epithelial cell apoptosis and inhibits TGF-β induced epithelial to mesenchymal transition
|
Zheng, ShengXing
|
|
|
177 |
C |
p.
|
artikel
|
| 82 |
Voltage-induced structural modifications on M2 muscarinic receptor and their functional implications when interacting with the superagonist iperoxo
|
López-Serrano, Ana Laura
|
|
|
177 |
C |
p.
|
artikel
|
Tijdschrift beschrijving