Chemical Compositions and Cytotoxic Activities of Leaf Essential Oils of Four Lauraceae Tree Species from Monteverde, Costa Rica
Titel:
Chemical Compositions and Cytotoxic Activities of Leaf Essential Oils of Four Lauraceae Tree Species from Monteverde, Costa Rica
Auteur:
Maria C. Palazzo Brittany R. Agius Brenda S. Wright William A. Haber Debra M. Moriarity William N. Setzer
Verschenen in:
Records of natural products
Paginering:
Jaargang 3 (2009) nr. 1 pagina's 32-37
Jaar:
2009
Inhoud:
The leaf essential oils of four members of the Lauraceae Licaria excelsa, Licaria triandra, Perseaschiedeana, and Rhodostemonodaphne kunthiana, from Monteverde, Costa Rica, were obtained byhydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS). The leaf oil of L. excelsawas dominated by the monoterpenes a-pinene (42.9%), b-pinene (22.0%) and myrcene (17.2%), while L.triandra was also rich in pinenes (40.9% and 28.5%, respectively). Persea schiedeana had considerableamounts of the sesquiterpenes d-cadinene (18.5%), a-copaene (15.1%), and (E)-caryophyllene (13.3%).Rhodostemonodaphne kunthiana leaf oil had germacrene D (64.4%) and bicyclogermacrene (17.6%) as themajor components. The leaf essential oils were screened for in-vitro cytotoxic activity against MDA-MB-231and Hs 578T human tumor cells. R. kunthiana leaf oil showed notable activity against MDA-MB-231.