Bacterial species: etiologic agents of nosocomial infections
Titel:
Bacterial species: etiologic agents of nosocomial infections
Auteur:
Stanca L. Pandrea Manuela Tompa Doina Matinca
Verschenen in:
Human & veterinary medicine
Paginering:
Jaargang 2 (2010) nr. 2 pagina's 68-76
Jaar:
2010
Inhoud:
Objective: evaluation of different bacterial species involved in etiology of nosocomial infectionsand joint analysis of nosocomial infections with multiple etiologies. Material and Methods: duringJanuary-July 2010 in the SPCIN (Prevention and Control of Nosocomial Infections Department) ofEmergency Clinical Hospital “Prof. Dr. O. Fodor” Cluj-Napoca, we have investigated a number of 201nosocomial infections. The blood cultures have been processed using the Bactec system, the rest ofsamples have been processed through conventional methods. The strains have been identified throughclassical biochemical methods and through Vitek 2 Compact (BioMerieux) system. Results: nosocomialinfections were analyzed by infection site and pathogen distribution. Most frequent types werebronchopneumonia (30%), postoperative wound infections (24%), followed by urinary tract infections(17%) and septicemia (17%). Approximately 36.5% of bloodstream infections were associated withcentral lines, 82.4% of nosocomial pneumonia were associated with mechanical ventilation and 54.4% ofurinary tract infections were associated with urinary catheters. Coagulase-negative staphylococci (18%)and Acinetobacter baumannii(18%) were the most common bloodstream infections isolates. The mostfrequent isolates from urinary tract infections were Enterococcus spp. (20%) and Candida tropicalis(20%).The most frequent isolates from postoperative wound infections were A. baumannii (20%) andKlebsiella pneumoniae (14%). From pneumonia isolates, the most frequent were Gram–negativeorganisms (72%). A. baumannii (40%) was the most frequently isolated of these, followed by K.pneumoniae (12%), Staphylococcus aureus (12%) and Pseudomonas aeruginosa (8%). Conclusion: themost frequent types of nosocomial infections were bronchopneumonia (30%), especially in intensive careunits (45%), followed by septicemia (23%). Regarding the isolated microorganisms, it is noted anincreased frequency or Gram-negative organisms (60%), both enterobacteria (30%) and nonfermenterspecies (30%). The most frequently isolated was A. baumannii, alone or in bacterial association.Approximately 8% of isolates were fungi. Certain pathogens were associated with device use: coagulase-negative staphylococci with central lines, fungal infections with urinary catheters, A. baumannii and P.aeruginosa with ventilators.