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Details for article 8 of 16 found articles
| Title: |
Effects of Antioxidant Vitamin Combination on Pregnancy Induced Hyper-Hepatic State |
| Author: |
O.I. Iribhogbe J.E. Emordi E.O. Nwoke B.O. Idonije U. Akpamu |
| Appeared in: |
International journal of pharmacology |
| Paging: | Volume 7 (2011) nr. 3 pages 376-381 |
| Year: |
2011 |
| Contents: |
<![CDATA[The purpose of this present study is to determine the influence of varying combinations of antioxidant Vitamins on the hyper-hepatic state of pregnancy. To achieve this, seventy pregnant Wister albino rats weighing between 250-300 g were procured and grouped into 2 control groups treated with distilled water and vehicle- tween-80, respectively and three cohorts (I, II and III) with four sub-groups each (n = 5). Starting from the 7th day, group I received a varying dose combination of Vitamin A+C, group II Vitamin A+E and group III Vitamin C+E respectively for 11 days. Results of liver function assay revealed that supplementation with Vitamin A+C, A+E and C+E caused a significant reduction (p<0.05) in serum protein and a non-significant (p>0.05) alteration in serum albumin. Except for ALT where Vitamin A+E combination produced no significant alteration, serum AST (Aspartate transaminase) and ALP (Alanine transaminase) were significantly reduced (p<0.05) with antioxidant Vitamin combination therapy when compared with control. Antioxidant vitamin combination may be advantageous in pregnancy induced hyper- hepatic state. However, further study is needed in this respect.]]> |
| Publisher: |
Asian Network for Scientific Information (provided by DOAJ) |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 8 of 16 found articles
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