Seroprevalence of Hepatitis C in a Sample of Middle Class Substance Abusers
Title:
Seroprevalence of Hepatitis C in a Sample of Middle Class Substance Abusers
Author:
Abraham, Henry David Degli-Esposti, Silvia Marino, Louis
Appeared in:
Journal of addictive diseases
Paging:
Volume 18 (1999) nr. 4 pages 77-87
Year:
1999-12-09
Contents:
Hepatitis C (HCV) is an indolent and often fatal disease affecting four million Americans commonly associated with low socio-economic status. We assessed its prevalence in a sample of 334 consecutively admitted middle class substance abusers in a private urban hospital, and ascertained risk factors for its transmission. We found that the point prevalence rate for HCV was 27.7% among all substance abusers, and 76.7% among intravenous drug users. Using logistic regression, we found risk factors associated with HCV were intravenous drug use, needle sharing, prior liver disease, opioid dependence, HIV infection, and benzodiazepine dependence. Not found to increase infective risk were lower social class, male gender, African-American race, male homosexuality, unemployment, and the absence of private health insurance. Multiple viral genotype types were identified in this sample, suggesting diverse sources of transmission in the sample. This study documents an epidemic of HCV in an American middle class sample.