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                                       Details for article 9 of 18 found articles
 
 
  Impact of β-Sheet Conformations on the Mechanical Response of Protein in Biocomposites
 
 
Title: Impact of β-Sheet Conformations on the Mechanical Response of Protein in Biocomposites
Author: Ghosh, Pijush
Katti, Dinesh R.
Katti, Kalpana S.
Appeared in: Materials and manufacturing processes
Paging: Volume 21 (2006) nr. 7 pages 676-682
Year: 2006-10-01
Contents: Proteins in biological nanocomposites play an important role in their mechanical response. Proteins in nacre, the inner layer of seashells, have been shown to have exceptional mechanical properties. One of the important nacre proteins, Lustrin-A, has abundance of polypeptides in zig-zag conformation called β-sheets. β-sheets of protein when present close to each other in multiple numbers could take the shape of a planar β-sheath like structure or a β-barrel to form a domain. In natural proteins both these types of structures are commonly found. However, the conformation of β-sheets in Lustrin-A is not known at this time. Effort has been made through this work to study the mechanical response of these β-planar sheath and β-barrel structures when subjected to external loads. Comparative study of the stress-deformation characteristics of these two types of structures has been made. Both these structures with almost similar number of amino acids have been extracted from one single spinach protein: Ferredoxin Reductase (1FNR). Steered molecular dynamics has been used to conduct these studies. The article deals with the separation of the two domains from the main protein, simulation details, and results comparing the responses.
Publisher: Taylor & Francis
Source file: Elektronische Wetenschappelijke Tijdschriften
 
 

                             Details for article 9 of 18 found articles
 
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