Influence of Cyclodextrin Complexation on the Vibrio fischeri Toxicity of Phenylsulfonyl Carboxylates
Title:
Influence of Cyclodextrin Complexation on the Vibrio fischeri Toxicity of Phenylsulfonyl Carboxylates
Author:
Liu, Xin H. Hou, Juan Wang, Lei Luo, Wen R. Cui, Bao S.
Appeared in:
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
Paging:
Volume 42 (2007) nr. 2 pages 149-153
Year:
2007-02
Contents:
This paper describes the research about the β -cyclodextrin influence on Vibrio fischeri toxicity of 10 phenylsulfonyl carboxylates. It is illustrated that the formation of 1:1 cyclodextrin-solute inclusion complexes dominates the toxicity influence of phenylsulfonyl carboxylates to Vibrio fischeri and greatly weakens the toxicity level. Using the octanol-water partition coefficients lg KOW, the grouped electrotopological state (E-state) index S(> SO2) and the stability constants of inclusion complexes lg KS, three models with high squared correlation coefficients r2adj at 0.908, 0.951 and 0.917, respectively were constructed to evaluate the β-cyclodextrin influence on Vibrio fischeri toxicity. For the type of phenylsulfonyl carboxylates, the inclusion stability constants lg KS can reliably model and predict the β-cyclodextrin influence on Vibrio fischeri toxicity (TI).