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Details for article 55 of 101 found articles
| Title: |
Microemulsion of Tween-80/n-Butylalcohol/H2O System and Its Entrapment Efficiency of ATRA |
| Author: |
Gu, Ming-Yan Wang, Zheng-Wu Yu, Hui-Xin Li, Gan-Zuo |
| Appeared in: |
Journal of dispersion science and technology |
| Paging: | Volume 27 (2006) nr. 7 pages 949-954 |
| Year: |
2006-10-01 |
| Contents: |
Microemulsion of Tween-80/n-butylalcohol/H2O system was prepared, and the microemulsion region as well as the influence of temperature and concentration of NaCl on the region were determined with ternary diagrams. The O/W, W/O, and B.C. regions were divided by the conductance method. The particle diameters of microemulsions with different NaCl concentrations or microemulsion-enveloping all-trans retinoic acid (ATRA) were measured with dynamic light scattering in O/W region. The release rate of ATRA was studied with dialysis a bag-ultraviolet spectrophotometers and the anticancer activity of ATRA in microemulsion was investigated with cancer cells H446. Results showed that O/W microemulsion forms when water content is over 64% in the mixture. The influences of temperature and salinity on microemulsion region were very slight, and even the particle diameter decreased very little with increasing salt and ATRA concentrations. The microemulsion-enveloping ATRA possessed eminent sustaining release efficiencys and the efficiency was further confirmed with the growth inhibitory effect test on human cancer cells H446. |
| Publisher: |
Taylor & Francis |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 55 of 101 found articles
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