Synthesis, characterization and antimicrobial activities of transition metal complexes of N,N-dialkyl-N'-(2-chlorobenzoyl)thiourea derivatives
Title:
Synthesis, characterization and antimicrobial activities of transition metal complexes of N,N-dialkyl-N'-(2-chlorobenzoyl)thiourea derivatives
Author:
Binzet, Gun Arslan, Hakan Florke, Ulrich Kulcu, Nevzat Duran, Nizami
Appeared in:
Journal of coordination chemistry
Paging:
Volume 59 (2006) nr. 12 pages 1395-1406
Year:
2006-08-05
Contents:
N,N-di-n-propyl-N'-(2-chlorobenzoyl)thiourea (HL1) (1), N,N-diphenyl-N'-(2-chlorobenzoyl)thiourea (HL2) (2), and their NiII, CoII, CuII, ZnII, PtII, CdII and PdII complexes have been synthesized and characterized. HL1 and its copper complex were characterized by single-crystal X-ray diffraction methods. The ligands coordinate as bidentates yielding essentially neutral complexes of the type [ML2]. The complexes were screened for their in vitro antibacterial, antifungal activities and toxicity. All compounds showed antimicrobial activity, but antibacterial efficacy is greater than antifungal activity.