Cognitive deficits in essential tremor consistent with frontosubcortical dysfunction
Titel:
Cognitive deficits in essential tremor consistent with frontosubcortical dysfunction
Auteur:
Higginson, Christopher I. Wheelock, Vicki L. Levine, Dawn King, David S. Pappas, Conrad T. E. Sigvardt, Karen A.
Verschenen in:
Journal of clinical and experimental neuropsychology
Paginering:
Jaargang 30 (2008) nr. 7 pagina's 760-765
Jaar:
2008-10
Inhoud:
Essential tremor (ET) is increasingly thought to involve a heterogeneous group of patients, with some also exhibiting symptoms of Parkinson's disease (PD), including cognitive deficits. The goal of this study was to utilize a broad battery of neuropsychological measures to compare the cognitive function of 33 ET patients with that of 33 matched PD patients and 21 normal controls. Results indicated that the ET group performed significantly worse than controls across multiple cognitive domains, but performed remarkably similar to PD patients, consistent with frontosubcortical dysfunction.