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                                       Details van artikel 8 van 15 gevonden artikelen
 
 
  Four new triterpenoid saponins from Ardisia gigantifolia Stapf. and their cytotoxic activity
 
 
Titel: Four new triterpenoid saponins from Ardisia gigantifolia Stapf. and their cytotoxic activity
Auteur: Wen, Ping
Zhang, Xiao-Ming
Yang, Zhu
Wang, Nai-Li
Yao, Xin-Sheng
Verschenen in: Journal of Asian natural products research
Paginering: Jaargang 10 (2008) nr. 9 pagina's 873-880
Jaar: 2008-09
Inhoud: Four new oleanane-type triterpenoid saponins, cyclamiretin A 3β-O-α-l-rhamnopyranosyl-(1 → 3)-[β-d-xylopyranosyl-(1 → 2)]-β-d-glucopyranosyl-(1 → 4)-[β-d-glucopyranosyl-(1 → 2)]-α-l-arabinopyranoside (1), cyclamiretin A 3β-O-α-l-rhamnopyranosyl-(1 → 3)-[β-d-glucopyranosyl-(1 → 3)-β-d-xylopyranosyl-(1 → 2)]-β-d-glucopyranosyl-(1 → 4)-[β-d-glucopyranosyl-(1 → 2)]-α-l-arabinopyranoside (2), cyclamiretin A 3β-O-α-l-rhamnopyranosyl-(1 → 3)-[β-d-xylopyranosyl-(1 → 2)]-β-d-glucopyranosyl-(1 → 4)-[β-d-6-O-acetylglucopyranosyl-(1 → 2)]-α-l-arabinopyranoside (3) and 3β-O-{α-l-rhamnopyranosyl-(1 → 3)-[β-d-xylopyranosyl-(1 → 2)]-β-d-glucopyranosyl-(1 → 4)-[β-d-glucopyranosyl-(1 → 2)]-α-l-arabinopyranoside}-16,28-dihydroxy-30-acetoxyoleana-12-en (4), along with one known triterpene saponin and ardisiacrispin A (5) were isolated from the rhizome of Ardisia gigantifolia. Their structures were established with the help of extensive spectroscopic techniques. Furthermore, the inhibitory effects of compounds on tumor cells (MTT based) in vitro were evaluated, and compounds 1, 2, and 5 showed potent anti-tumor activities.
Uitgever: Taylor & Francis
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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