Synthesis and enantiomeric resolution of (±)-pinocembrin
Titel:
Synthesis and enantiomeric resolution of (±)-pinocembrin
Auteur:
Yuan, Yue Yang, Qing-Yun Tong, Yuan-Feng Chen, Feng Qi, Yan Duan, Ya-Bo Wu, Song
Verschenen in:
Journal of Asian natural products research
Paginering:
Jaargang 10 (2008) nr. 10 pagina's 999-1002
Jaar:
2008-10
Inhoud:
A convenient method for the synthesis and enantiomeric resolution of ( ± )-pinocembrin has been developed. This route involves the hydrogenation of 5,7-dihydroxyflavone, the derivatization of racemic pinocembrin with chiral amine, and the separation of the diastereoisomers due to their different physical properties.