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Details for article 9 of 29 found articles
| Title: |
Isolation, structure determination and biological activity of a new glutarimide antibiotic, S632A3 |
| Author: |
Cheng, Chun-Lei Liu, Qiong-Yan Chen, Li-Hui Jin, Wen-Zao Si, Shu-Yi Li, Dian-Dong |
| Appeared in: |
Journal of Asian natural products research |
| Paging: | Volume 8 (2006) nr. 1-2 pages 55-60 |
| Year: |
2006-01 |
| Contents: |
A new antibiotic, S632A3, was isolated from a cultured broth of Streptomyces hygroscopicus S632. It was purified by column chromatography on silica gel, Sephadex LH-20 and HPLC. Structural studies by analysis of 1H NMR and 13C NMR, MS, UV and IR spectra in comparison with those of S632A2 clarified that S632A3 is an isomer of 9-methylstreptimidone. In addition, this antibiotic showed potent biological activity including differentiation induction effects on HL-60 cell and antitumour activity in vivo. |
| Publisher: |
Taylor & Francis |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 9 of 29 found articles
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