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                                       Details van artikel 165 van 222 gevonden artikelen
 
 
  Range-Finding Study of Risk Factors for Childhood Asthma Development and National Asthma Prevalence
 
 
Titel: Range-Finding Study of Risk Factors for Childhood Asthma Development and National Asthma Prevalence
Auteur: Bukowski, John A.
Lewis, R. Jeffrey
Gamble, John F.
Wojcik, Nancy C.
Laumbach, Robert J.
Verschenen in: Human and ecological risk assessment
Paginering: Jaargang 8 (2002) nr. 4 pagina's 735-765
Jaar: 2002-10-01
Inhoud: This review explores the recent epidemiological literature to identify possible risk factors for childhood asthma development, as well as the proportion of cases that might be attributable to each factor. Tobacco smoke and house-dust-mite allergy are the only environmental risk factors with firmly established roles in asthma development. Together with genetics, these risk factors probably account for much of childhood asthma development. Suggestive risk factors include cockroach, pet, and mold allergens; low birth weight; small family size; and viral infection. More theoretical risk factors include insufficient breastfeeding, obesity/inactivity, ambient ozone, and living in non-farm settings. National/international trends suggest several risk factors that could play major roles in the rising prevalence of asthma. The “tighter” building construction of modern housing and the increasing time that children spend indoors has undoubtedly increased indoor allergen exposures. Children also spend more time in sedentary activities, with a concomitant decrease in physical activity and increase in obesity. Modern “hygiene” and the changing nature of childhood infection may have also increased asthma prevalence. Mechanisms have been suggested implicating ambient air pollution in asthma development, and there is limited epidemiological evidence supporting this hypothesis. However, this evidence does not resolve why pollution levels have been decreasing throughout the period that asthma rates have risen
Uitgever: Taylor & Francis
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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