Toxicity Assessment Of Phycocyanin - A Blue Colorant From Blue Green Alga Spirulina platensis
Titel:
Toxicity Assessment Of Phycocyanin - A Blue Colorant From Blue Green Alga Spirulina platensis
Auteur:
Naidu, K. Akhilender Sarada, R. Manoj, G. Khan, M. Y. Swamy, M. Mahadeva Viswanatha, S. Murthy, K. Narasimha Ravishankar, G. A. Srinivas, Leela
Verschenen in:
Food biotechnology
Paginering:
Jaargang 13 (1996) nr. 1 pagina's 51-66
Jaar:
1996
Inhoud:
Phycocyanin, a blue colorant from the cyanobacterium (blue green alga) Spirulina platensis was evaluated for its safety as a natural food colour by toxicity evaluation studies in albino rats. Acute and subchronic studies on phycocyanin were conducted on both sexes of albino rats. Phycocyanin at high concentrations- 0.25 to 5.0 g/kg body weight (w/w) did not induce any symptoms of toxicity nor mortality of the animals. Feeding of low concentrations of phycocyanin at 0.5 to 4.0 g/kg in the diet for 14 weeks did not affect food intake or body weight gain of phycocyanin-fed rats compared to control animals. Terminal values on absolute and relative weights of vital organs, hematology and serum enzymes did not reveal any differences between phycocyanin-fed and control groups. Histological examination of vital organs did not show any remarkable differences between treated and control groups. Overall, consumption of phycocyanin, a natural colorant from Spirulina platensis did not result in adverse effects in experimental animals.