Circadian Rhythms of Histatin 1, Histatin 3, Histatin 5, Statherin and Uric Acid in Whole Human Saliva Secretion
Titel:
Circadian Rhythms of Histatin 1, Histatin 3, Histatin 5, Statherin and Uric Acid in Whole Human Saliva Secretion
Auteur:
Castagnola, M. Cabras, T. Denotti, G. Fadda, M. B. Gambarini, G. Lupi, A. Manca, I. Onnis, G. Piras, V. Soro, V. Tambaro, S. Messana, I.
Verschenen in:
Biological rhythm research
Paginering:
Jaargang 33 (2002) nr. 2 pagina's 213-222
Jaar:
2002-04
Inhoud:
The circadian rhythms of histatins 1, 3, 5, of statherin and uric acid were investigated in whole human saliva. Histatins showed a rhythm approximately synchronous with salivary flow rate (acrophase around 5 pm), the higher amplitude pertaining to histatin 1 (about 50% of the mesor). Uric acid showed a large rhythm asynchronous with flow rate and histatin concentrations (4.4 ± 1.4 am). Statherin did not show a significant circadian rhythm on five of six volunteers. This finding confirms that the secretion route of statherin is different from that of histatins.