|
| volgende >> |
Tijdschrift beschrijving
Alle jaargangen van het bijbehorende tijdschrift
Alle afleveringen van het bijbehorende jaargang
Alle artikelen van de bijbehorende aflevering
Details van artikel 1 van 10 gevonden artikelen
| Titel: |
A orcadian response to 5-HTP inhibition of locomotion in the earthworm, lumbricus terrestris |
| Auteur: |
Burns, John T. Bennett, James R. Desmond, Robert E. Meloy, Jennifer G. Mielke, Amy L. Six, John D. |
| Verschenen in: |
Biological rhythm research |
| Paginering: | Jaargang 22 (1991) nr. 3 pagina's 255-260 |
| Jaar: |
1991-09 |
| Inhoud: |
The effect of DL-p-chlorophenylalanine (PCPA) and 5-hydroxy-L-tryptophan (5-HTP), which influence serotonin levels, were studied with respect to locomotion rates in earthworms, Lumbricus terrestris. The drugs were dissolved in .65% saline and injected into the coelom, and then the rate of locomotion was determined 6 hours later. PCPA, which inhibits serotonin synthesis, increased the rate of locomotion across a distance of 10 cm (19.07 ± 1.07 seconds) as compared to the rate of saline-injected controls (28.56 ± .96 seconds). In general, saline-injected earthworms crawled faster than 5-HTP-injected earthworms (Student's t test P value less than .0005). Earthworms injected with saline at one of four times of the day crawled fastest at 2400 following injections at 1800 and the responses showed a circadian rhythm (ANOVA P value less than .005 and Cosinor P value less than .001). Earthworms injected 6 hours previously with 5-HTP crawled slowest at 2400 as compared to the 2400 controls. Among the four times of day, 0600,1200,1800 or 2400 when the locomotion rate was determined, the responses to 5-HTP showed a circadian rhythm (ANOVA P value less than .025 and Cosinor P value less than .017). These results should be taken into consideration when designing or interpreting experiments on neurotransmitters in earthworms and other annelids. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 1 van 10 gevonden artikelen
| volgende >> |