|
| << vorige | volgende >> |
Tijdschrift beschrijving
Alle jaargangen van het bijbehorende tijdschrift
Alle afleveringen van het bijbehorende jaargang
Alle artikelen van de bijbehorende aflevering
Details van artikel 7 van 9 gevonden artikelen
| Titel: |
Orcadian regulation of RNA polymerases and nuclease sensitivity in rat liver nuclei |
| Auteur: |
Horseman, Nelson D. Will, Cindy L. |
| Verschenen in: |
Biological rhythm research |
| Paginering: | Jaargang 15 (1984) nr. 3 pagina's 169-178 |
| Jaar: |
1984-11 |
| Inhoud: |
Circadian cycles at various levels of transcriptional regulation were tested by assaying endogenous DNA-dependent RNA polymerases I and II and chromatin structure as revealed by DNase I and micrococcal nuclease digestion. In rat liver nuclei, RNA polymerases I and II exhibited circadian cycles in their activities; pol II peaked 10 hours after the beginning of subjective day and pol I peaked 8 hours later. A marked circadian variation of DNase I sensitivity, corresponding closely in phase and amplitude with the pol II rhythm, was also observed. However, no circadian variation in nudeosome content was detected by micrococcal nuclease digestion. The novel finding of a circadian variation in chromatin sensitivity to nuclease suggests potential mechanisms for the regulation of circadian changes in gene action. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 7 van 9 gevonden artikelen
| << vorige | volgende >> |