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The effects of pH on the enzymatic formation of β-glucuronides of various retinoids by induced and noninduced microsomal UDPGA-glucuronosyltransferases of several rat tissues in vitro 1 1 Abbreviations used: acitretin, 9-(2′,3′,6′ trimethyl, 4′methoxybenzyl-1′) 3,7 dimethyl, nona-2,4,6,8 tetraenoic acid; acitretin-G, acitretin-glucuronide; BHT, butylated hydroxytoluene; CD-367, tetramethyl, tetrahydro-anthracenyl-benzoic acid; CD-367-G, CD-367 glucuronide; HPLC, high-performance liquid chromatography; 3MC, 3-methylcholanthrene; MES, 2-[N-morpholino]ethanesulfonic acid; NEM, N-ethylmaleimide; 4-oxo-RA, 4-oxoretinoic acid; 4-oxo-RAG, 4-oxoretinoyl β-glucuronide; RA, retinoic acid; RAG, retinoyl β-glucuronide; RAR, retinoic acid receptor; ROL, retinol; RXR, retinoid X receptor; Tris, tris [hydroxymethyl] aminomethane; TTNPB, tetramethyl, tetrahydronaphthenyl-propenyl-benzoic acid; TTNPB-G, TTNPB glucuronide; UDPGA, UDP-glucuronic acid; UGT, UDPGA-glucuronosyl transferase. |
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Title: |
The effects of pH on the enzymatic formation of β-glucuronides of various retinoids by induced and noninduced microsomal UDPGA-glucuronosyltransferases of several rat tissues in vitro 1 1 Abbreviations used: acitretin, 9-(2′,3′,6′ trimethyl, 4′methoxybenzyl-1′) 3,7 dimethyl, nona-2,4,6,8 tetraenoic acid; acitretin-G, acitretin-glucuronide; BHT, butylated hydroxytoluene; CD-367, tetramethyl, tetrahydro-anthracenyl-benzoic acid; CD-367-G, CD-367 glucuronide; HPLC, high-performance liquid chromatography; 3MC, 3-methylcholanthrene; MES, 2-[N-morpholino]ethanesulfonic acid; NEM, N-ethylmaleimide; 4-oxo-RA, 4-oxoretinoic acid; 4-oxo-RAG, 4-oxoretinoyl β-glucuronide; RA, retinoic acid; RAG, retinoyl β-glucuronide; RAR, retinoic acid receptor; ROL, retinol; RXR, retinoid X receptor; Tris, tris [hydroxymethyl] aminomethane; TTNPB, tetramethyl, tetrahydronaphthenyl-propenyl-benzoic acid; TTNPB-G, TTNPB glucuronide; UDPGA, UDP-glucuronic acid; UGT, UDPGA-glucuronosyl transferase. |
Author: |
Genchi, Giuseppe Barua, Arun B Wang, Wei Bidlack, Wayne R Olson, James A |
Appeared in: |
Journal of nutritional biochemistry |
Paging: |
Volume 9 (1998) nr. 12 pages 6 p. |
Year: |
1998 |
Contents: |
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Publisher: |
Elsevier Science Inc. |
Source file: |
Elektronische Wetenschappelijke Tijdschriften |
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