Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ1–40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimer's disease
Titel:
Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ1–40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimer's disease
Auteur:
Sajan, Mini P. Hansen, Barbara C. Higgs, Margaret G. Kahn, C. Ron Braun, Ursula Leitges, Michael Park, Collin R. Diamond, David M. Farese, Robert V.